Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Akiyoshi Uezu"'
Autor:
Erin F. Spence, Shataakshi Dube, Akiyoshi Uezu, Margaret Locke, Erik J. Soderblom, Scott H. Soderling
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The internal molecular mechanisms that underlie excitatory synaptogenesis remain poorly characterized. This study utilizes a chemogenetic approach, in vivo biotin identification (iBioID), to discover previously uncharacterized proteins at nascent syn
Externí odkaz:
https://doaj.org/article/e43c74abbac949eab8b79559b2c2b33a
Autor:
Akiyoshi Uezu, Erin Hisey, Yoshihiko Kobayashi, Yudong Gao, Tyler WA Bradshaw, Patrick Devlin, Ramona Rodriguiz, Purushothama Rao Tata, Scott Soderling
Publikováno v:
eLife, Vol 8 (2019)
Human mutations in the dystroglycan complex (DGC) result in not only muscular dystrophy but also cognitive impairments. However, the molecular architecture critical for the synaptic organization of the DGC in neurons remains elusive. Here, we report
Externí odkaz:
https://doaj.org/article/962ab3557d38497e91e4e12fb85d02bf
Autor:
W Christopher Risher, Sagar Patel, Il Hwan Kim, Akiyoshi Uezu, Srishti Bhagat, Daniel K Wilton, Louis-Jan Pilaz, Jonnathan Singh Alvarado, Osman Y Calhan, Debra L Silver, Beth Stevens, Nicole Calakos, Scott H Soderling, Cagla Eroglu
Publikováno v:
eLife, Vol 3 (2014)
During cortical synaptic development, thalamic axons must establish synaptic connections despite the presence of the more abundant intracortical projections. How thalamocortical synapses are formed and maintained in this competitive environment is un
Externí odkaz:
https://doaj.org/article/b90e1976a60c4962957813477cb052d4
Autor:
Hirokazu Okada, Akiyoshi Uezu, Erik J Soderblom, M Arthur Moseley, Frank B Gertler, Scott H Soderling
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37035 (2012)
Many protein interaction domains bind short peptides based on canonical sequence consensus motifs. Here we report the development of a peptide array-based proteomics tool to identify proteins directly interacting with ligand peptides from cell lysate
Externí odkaz:
https://doaj.org/article/d720d3abd22b423bafa96bd78fac8cda
Autor:
Tohru Hosoyama, Minako Kawai‐Takaishi, Hiroki Iida, Yoko Yamamoto, Yuko Nakamichi, Tsuyoshi Watanabe, Marie Takemura, Shigeaki Kato, Akiyoshi Uezumi, Yasumoto Matsui
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 3, Pp 907-918 (2024)
Abstract Background Recent studies have indicated the importance of muscle quality in addition to muscle quantity in sarcopenia pathophysiology. Intramuscular adipose tissue (IMAT), which originates from mesenchymal progenitors (MPs) in adult skeleta
Externí odkaz:
https://doaj.org/article/4c940c74c6534e5d8f25284e96a75436
Autor:
Scott H. Soderling, Erik J. Soderblom, Patricia F. Maness, Tetsuya Takano, Katherine T. Baldwin, Jamie L Courtland, Akiyoshi Uezu, Alicia Purkey, John T Wallace, Tomomi Shimogori, Cagla Eroglu
Publikováno v:
Nature
Summary Perisynaptic astrocyte processes are an integral part of central nervous system synapses1,2; however, the molecular mechanisms governing astrocyte-synapse adhesions and how astrocyte contacts control synapse formation and function are largely
SUMMARYThe C2-WW-HECT domain ubiquitin ligase Nedd4L regulates sorting in endocytosis by mediating ubiquitination of cargo molecules, such as the epithelial sodium channel (ENaC). Defects in ENaC ubiquitination cause Liddle syndrome, a hereditary hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d925979638b4d6d8cb3ddc47141e3d77
https://doi.org/10.1101/2022.02.21.481372
https://doi.org/10.1101/2022.02.21.481372
Map7D2 and Map7D1 facilitate microtubule stabilization through distinct mechanisms in neuronal cells
Autor:
Kenji Shimamura, Yasuhisa Sakamoto, Hiroyuki Nakanishi, Hideyuki Yamamoto, Kei-ichiro Ishiguro, Akiyoshi Uezu, Taro Saito, Koji Kikuchi, Shin-ichi Hisanaga
Publikováno v:
Life science alliance. 5(8)
Microtubule (MT) dynamics are modulated through the coordinated action of various MT-associated proteins (MAPs). However, the regulatory mechanisms underlying MT dynamics remain unclear. Herein, we show that MAP7 family protein Map7D2 facilitates MT
Autor:
Hiroyuki Nakanishi, Shin-ichi Hisanaga, Taro Saito, Kenji Shimamura, Kei-ichiro Ishiguro, Hideyuki Yamamoto, Akiyoshi Uezu, Yasuhisa Sakamoto, Koji Kikuchi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57e449b3e6657338ef528619f5286086
https://doi.org/10.15252/rc.2022405099
https://doi.org/10.15252/rc.2022405099
Autor:
Koji Kikuchi, Yasuhisa Sakamoto, Akiyoshi Uezu, Hideyuki Yamamoto, Kei-ichiro Ishiguro, Kenji Shimamura, Taro Saito, Shin-ichi Hisanaga, Hiroyuki Nakanishi
Publikováno v:
Life Science Alliance; Aug2022, Vol. 5 Issue 8, p1-15, 15p