Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Akiyoshi Moriwaki"'
Autor:
Tadashi Yoshino, Ryuzo Ueda, Isao Date, Akiyoshi Moriwaki, Nobuya Ohara, Koichi Ichimura, Kazuhiro Yoshikawa, Masaki Adachi, Masahiko Hirai, Tomotsugu Ichikawa, Takayoshi Miyake, Takehiro Tanaka, Eisaku Kondo
Molecular targeting agents have become formidable anticancer weapons, which show much promise against the refractory tumors. Functional peptides are among the more desirable of these nanobio-tools. Intracellular delivery of multiple functional peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7e6f5ef0cb3b1c03b2a042771abfa5
https://doi.org/10.1158/1535-7163.c.6531570.v1
https://doi.org/10.1158/1535-7163.c.6531570.v1
Autor:
Tadashi Yoshino, Ryuzo Ueda, Isao Date, Akiyoshi Moriwaki, Nobuya Ohara, Koichi Ichimura, Kazuhiro Yoshikawa, Masaki Adachi, Masahiko Hirai, Tomotsugu Ichikawa, Takayoshi Miyake, Takehiro Tanaka, Eisaku Kondo
Supplementary Fig. from Potent synergy of dual antitumor peptides for growth suppression of human glioblastoma cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b344dc43fdaf17fd9abbf13fab08bc48
https://doi.org/10.1158/1535-7163.22484760
https://doi.org/10.1158/1535-7163.22484760
Publikováno v:
The Journal of Reproduction and Development
Reproductive functions decline with the onset of diabetes in female mice. Diabetic mice have smaller uteri with an underdeveloped endometrium, suggesting diminished estrogen-induced growth. We aimed to clarify the changes in the estrous cycle and in
Publikováno v:
Acta Medica Okayama. 61(3):161-166
Oxytocin (OT) is one of the neuropituitary hormones and is synthesized in the neurons of the paraventricular nucleus (PVN) and supraoptic nucleus (SON). Previous studies have shown that the mRNAs encoding OT are delivered from the soma to both dendri
Autor:
Toshifumi Ozaki, Keiichirou Nishida, Aki Yoshida, Masayuki Matsushita, Shinya Arataki, Hajime Inoue, Kazuhito Tomizawa, Akiyoshi Moriwaki, Hideki Matsui, Toshiyuki Kunisada
Publikováno v:
Journal of Neurotrauma. 22:398-406
Traumatic spinal cord injury (SCI) results in widespread neuronal cell death. Recent studies have suggested that activated calpain mediates neuronal cell death in the central nervous system. We conducted a study to determine whether calpain mediates
Autor:
Masayuki Matsushita, Hideki Matsui, Sheng-Tian Li, Akiyoshi Moriwaki, Yoshiya Oda, Kazuhito Tomizawa, Fan Yan Wei, Yun Fei Lu, Hai Yan Wu
Publikováno v:
Journal of Biological Chemistry. 279:4929-4940
Calcineurin and calpain, a Ca2+/calmodulin-dependent protein phosphatase and a Ca2+-dependent cysteine protease, respectively, mediate neuronal cell death through independent cascades. Here, we report that during neuroexcitotoxicity, calcineurin A (C
Autor:
Akiyoshi Moriwaki, Yasunori Saheki, Hiroaki Terada, Kazuhito Tomizawa, Yun Fei Lu, Hideki Matsui, Hai Yan Wu, Masayuki Matsushita, Sheng-Tian Li
Publikováno v:
Annals of Neurology. 55:362-371
Although memory deficits have been clearly documented in patients with human immunodeficiency virus type-1 (HIV-1) infection, the physiological basis of this dysfunction is poorly understood. We focused on Tat, a viral protein released from HIV-1-inf
Autor:
Masayuki Matsushita, Takashi Ohmoto, Takeshi Shirai, Yun Fei Lu, Hideki Matsui, Shinsaku Nishio, Isao Date, Sheng-Tian Li, Kazuhito Tomizawa, Akiyoshi Moriwaki, Hiroaki Terada
Publikováno v:
Journal of Neurochemistry. 87:1145-1151
In glutamate-mediated excitatory neuronal cell death, immunosuppressants (FK506, Cys-A) are powerful agents that protect neurons from apoptosis. Immunosuppressants inhibit two types of enzyme, calcium/calmodulin-dependent protein phosphatase (calcine
Autor:
Sheng-Tian Li, Akiyoshi Moriwaki, Masayuki Matsushita, Hideki Matsui, Kazuhito Tomizawa, Hiroaki Terada
Publikováno v:
Scopus-Elsevier
Proteins and peptides have been demonstrated to penetrate across the plasma membrane of eukaryotic cells by protein transduction domains. We show that protein transduction by 11 arginine (11R) is an efficient method of delivering proteins into the ne
Autor:
Tadashi Yoshino, Akiyoshi Moriwaki, Mine Harada, Kazuhiro Mizoguchi, Shigeru Okada, Masatoshi Uno, Toshio Noguchi, Junjiroh Tsuchiyama, Tetsuya Ogino
Publikováno v:
British Journal of Haematology. 113:1009-1014
Epstein-Barr virus (EBV)-associated nasal T/natural killer (NK) cell lymphoma has often been reported in Asian countries and has been recently confirmed as a novel clinicopathological entity. The prognosis of advanced stage disease is quite poor and