Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Akiyo K. Claiborne"'
Publikováno v:
ChemInform. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d091be77dff2e3162221ab0adcb4d1e0
https://doi.org/10.1002/chin.199304195
https://doi.org/10.1002/chin.199304195
Publikováno v:
ChemInform. 24
A series of quinoline and naphthyridine antibacterial agents possessing an acyclic or cyclic gem-disubstituted piperazine substituent at the C-7 position have been prepared and evaluated in vitro a...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea5f3769adfffacc2b93f1f1a8f687fc
https://doi.org/10.1002/chin.199304196
https://doi.org/10.1002/chin.199304196
Publikováno v:
Canadian Journal of Chemistry. 70:1323-1327
An alternative synthesis of (±)-7-(3-methylpiperazin-1-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid hydrochloride 4, a potent antibacterial agent, was developed. The method was characterized by regiospecific displ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bff31a68d81810d63bf6d5efcd0663de
https://doi.org/10.1139/v92-170
https://doi.org/10.1139/v92-170
Publikováno v:
Canadian Journal of Chemistry. 70:1328-1337
A series of quinoline and naphthyridine antibacterial agents possessing an acyclic or cyclic gem-disubstituted piperazine substituent at the C-7 position have been prepared and evaluated in vitro and in vivo for antibacterial activity against a varie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e1e7bf6cba85e64ce65029ba4e647ca
https://doi.org/10.1139/v92-171
https://doi.org/10.1139/v92-171
Autor:
Deanne Crowell, Michael D. Tufano, Kennan C. Marsh, Kristine B. Berst, Jacob J. Plattner, Lisa A. Hasvold, Daniel T. W. Chu, Qun Li, Angela M. Nilius, Linus L. Shen, Weibo Wang, Kathleen Raye, Akiyo K. Claiborne, Jeff Alder, Robert K. Flamm
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(15)
The 8-position side chain of 2-pyridones is believed to be involved in the binding with bacterial DNA gyrase to form the ternary complex, making them very important for the activity of 2-pyridones. A series of 2-pyridones having fluoro-substituted am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93775667e7384571f427311a12afcffb
https://pubmed.ncbi.nlm.nih.gov/9873465
https://pubmed.ncbi.nlm.nih.gov/9873465
Autor:
Daniel T. W. Chu, Akiyo K. Claiborne
Publikováno v:
Journal of Heterocyclic Chemistry. 24:1537-1539
Short and efficient syntheses of 7-fluoro-8-(4-methylpiperazin-1-yl)-1,2,3,5-tetrahydro-5-oxopyrrolo[1,2-a]-quinoline-4-carboxylic acid and 8-fluoro-9-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-6H-6-oxopyrido[1,2-a]-quinoline-5-carboxylic acid are d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3eb9ade5b1099d03a32ea1ca98297ec
https://doi.org/10.1002/jhet.5570240608
https://doi.org/10.1002/jhet.5570240608
Autor:
Daniel T. W. Chu, Akiyo K. Claiborne
Publikováno v:
ChemInform. 19
Short and efficient syntheses of 7-fluoro-8-(4-methylpiperazin-1-yl)-1,2,3,5-tetrahydro-5-oxopyrrolo[1,2-a]-quinoline-4-carboxylic acid and 8-fluoro-9-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-6H-6-oxopyrido[1,2-a]-quinoline-5-carboxylic acid are d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad40d07232e9297370275bfb44dd7429
https://doi.org/10.1002/chin.198829218
https://doi.org/10.1002/chin.198829218