Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Akiva S Cohen"'
Autor:
Jaclynn eElkind, Miranda M Lim, Brian Neal Johnson, Chris P Palmer, Brendan J Putnam, Matthew P Kirschen, Akiva S Cohen
Publikováno v:
Frontiers in Neurology, Vol 6 (2015)
Traumatic brain injury (TBI) results in long-lasting cognitive impairments for which there is currently no accepted treatment. A well-established mouse model of mild to moderate TBI, lateral fluid percussion injury (FPI), shows changes in network exc
Externí odkaz:
https://doaj.org/article/658e9ef42ad34a5bb7e3d93b0da31120
Autor:
Elliot B Bourgeois, Brian N Johnson, Almedia J McCoy, Lorenzo Trippa, Akiva S Cohen, Eric D Marsh
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108686 (2014)
Voltage-sensitive dye imaging (VSDI) can simultaneously monitor the spatiotemporal electrical dynamics of thousands of neurons and is often used to identify functional differences in models of neurological disease. While the chief advantage of VSDI i
Externí odkaz:
https://doaj.org/article/fce538ad369e4de2b3ff99d8ee003993
Autor:
Guoxiang Xiong, Ian Jean, Anthony M. Farrugia, Hannah Metheny, Brian N. Johnson, Noam A. Cohen, Akiva S. Cohen
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Traumatic brain injury (TBI) is a leading cause of morbidity and mortality, especially in teenagers to young adults. In recent decades, different biomarkers and/or staining protocols have been employed to evaluate the post-injury development of patho
Externí odkaz:
https://doaj.org/article/5f458d43e26147a79f057fa7b6d967d7
Autor:
James P. Harris, Constance J. Mietus, Kevin D. Browne, Kathryn L. Wofford, Carolyn E. Keating, Daniel P. Brown, Brian N. Johnson, John A. Wolf, Douglas H. Smith, Akiva S. Cohen, John E. Duda, D. Kacy Cullen
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Closed-head traumatic brain injury (TBI) is induced by rapid motion of the head, resulting in diffuse strain fields throughout the brain. The injury mechanism(s), loading thresholds, and neuroanatomical distribution of affected cells remain poorly un
Externí odkaz:
https://doaj.org/article/6199c5a343c2489d9d4370f3f3f80d33
Autor:
Jonathan E. Elliott, Allison T. Keil, Sara Mithani, Jessica M. Gill, Maya E. O’Neil, Akiva S. Cohen, Miranda M. Lim
Publikováno v:
Frontiers in Systems Neuroscience, Vol 16 (2022)
Study ObjectivesTraumatic brain injury (TBI) is associated with chronic sleep disturbances and cognitive impairment. Our prior preclinical work demonstrated dietary supplementation with branched chain amino acids (BCAA: leucine, isoleucine, and valin
Externí odkaz:
https://doaj.org/article/6b15e4b952e945a6a2e522e083830d16
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Immunostaining is a powerful technique and widely used to identify molecules in tissues and cells, although critical steps are necessary to block cross-reaction. Here we focused on an overlooked cross immunoreactivity issue where a secondary antibody
Externí odkaz:
https://doaj.org/article/460413ad9f0b49cd96f359ad1c701dc0
Autor:
Guoxiang Xiong, Hannah Metheny, Kaitlin Hood, Ian Jean, Anthony M. Farrugia, Brian N. Johnson, Shanti R. Tummala, Noam A. Cohen, Akiva S. Cohen
Publikováno v:
Brain Pathology.
Publikováno v:
J Neurotrauma
Traumatic brain injury (TBI) is a serious public health problem associated with numerous physical and neuropsychiatric comorbidities. Chronic pain is prevalent and interferes with post-injury functioning and quality of life, whereas substance use dis
Publikováno v:
Frontiers in Neuroanatomy, Vol 11 (2017)
The hippocampus plays a critical role in learning and memory and higher cognitive functions, and its dysfunction has been implicated in various neuropathological disorders. Electrophysiological recording undertaken in live brain slices is one of the
Externí odkaz:
https://doaj.org/article/daceb0e213034c87b95914772c9240f5
Autor:
Ramon Diaz-Arrastia, Kaitlin A. Folweiler, Danielle K. Sandsmark, Akiva S. Cohen, Aaron J. Masino
Publikováno v:
J Neurotrauma
The heterogeneity of traumatic brain injury (TBI) remains a core challenge for the success of interventional clinical trials. Data-driven approaches for patient stratification may help to identify TBI patient phenotypes during the acute injury period