Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Akitsugu Matsui"'
Publikováno v:
Micromachines, Vol 11, Iss 4, p 426 (2020)
A combination of three-dimensional (3D) cell culturing and non-viral gene transfection is promising in improving outcomes of cell transplantation therapy. Herein, gene transfection profiles in 3D cell culture were compared between plasmid DNA (pDNA)
Externí odkaz:
https://doaj.org/article/309a2a13523f45e584db618739e6893e
Publikováno v:
Journal of Controlled Release. 285:1-11
Cell transplantation therapy needs engraftment efficiency improvement of transplanted cells to the host tissues. Ex vivo transfection of a pro-survival gene to transplanted cells is a possible solution; however prolonged expression and/or genomic int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172f690b2cd7a63acd71e06684f613a5
https://doi.org/10.1016/j.jconrel.2018.06.033
https://doi.org/10.1016/j.jconrel.2018.06.033
Autor:
Zhishen Ge, Kazunori Kataoka, Qixian Chen, Makoto Oba, Kensuke Osada, Yu Matsumoto, Akitsugu Matsui, Theofilus A. Tockary, Anjaneyulu Dirisala, Kazuko Toh, Takahiro Nomoto, Satoshi Uchida, Tekihiko Ishii, Kaori M. Takeda, Xueying Liu
Publikováno v:
Biomaterials. 113:253-265
Both efficiency and safety profiles are crucial for promotion of gene delivery systems towards practical applications. A promising template system was previously developed based on block catiomer of poly(ethylene glycol) (PEG)-b-poly{N'-[N-(2-aminoet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e995439ea2b08ee3a697225a3ae825
https://doi.org/10.1016/j.biomaterials.2016.10.042
https://doi.org/10.1016/j.biomaterials.2016.10.042
Autor:
Keiji Itaka, Kazunori Kataoka, Takehiko Ishii, Akitsugu Matsui, Hirokuni Uchida, Kaori Machitani Takeda, Kensuke Osada, Theofilus A. Tockary, Hiroaki Kinoh, Satoshi Uchida
Publikováno v:
Biomaterials. 82:221-228
Systemic delivery of messenger RNA (mRNA) is technically challenging because mRNA is highly susceptible to enzymatic degradation in the blood circulation. In this study, we used a nanomicelle-based platform, prepared from mRNA and poly(ethylene glyco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c957a545a9a16894f5b1a6c97f97810
https://doi.org/10.1016/j.biomaterials.2015.12.031
https://doi.org/10.1016/j.biomaterials.2015.12.031
Publikováno v:
Micromachines
Micromachines, Vol 11, Iss 426, p 426 (2020)
Micromachines, Vol 11, Iss 426, p 426 (2020)
A combination of three-dimensional (3D) cell culturing and non-viral gene transfection is promising in improving outcomes of cell transplantation therapy. Herein, gene transfection profiles in 3D cell culture were compared between plasmid DNA (pDNA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91db6942f2534b44a9a9ea6e07a92c9e
https://doi.org/10.3390/mi11040426
https://doi.org/10.3390/mi11040426
Publikováno v:
Scientific Reports
Gene therapy is a promising approach for treating diseases that are closely associated with excessive apoptosis, because the gene can effectively and sustainably introduce anti-apoptotic factors into cells. However, DNA delivery poses the risk of ran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2510ca4db9db7340c651e853b525edf7
https://doi.org/10.1038/srep15810
https://doi.org/10.1038/srep15810
Autor:
Masaru Ikegami, Keiji Itaka, Taisuke Endo, Kayoko Yanagihara, Takehiko Ishii, Akitsugu Matsui, Kazunori Kataoka, Satoshi Uchida
Publikováno v:
Journal of Visualized Experiments.
To improve the therapeutic effectiveness of cell transplantation, a transplantation system of genetically modified, injectable spheroids was developed. The cell spheroids are prepared in a culture system on micropatterned plates coated with a thermos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02fb5013d7b5c71f07445c60af9898fb
https://doi.org/10.3791/52384
https://doi.org/10.3791/52384