Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Akito, Tomomura"'
Publikováno v:
Medicines, Vol 8, Iss 8, p 41 (2021)
Blood calcium homeostasis is critical for biological function. Caldecrin, or chymotrypsin-like elastase, was originally identified in the pancreas as a serum calcium-decreasing factor. The serum calcium-decreasing activity of caldecrin requires the t
Externí odkaz:
https://doaj.org/article/2934ef00e44a4aca8d24f33803bff9d4
Autor:
Yoshiaki Sugita, Koichi Takao, Yoshihiro Uesawa, Akito Tomomura, Mineko Tomomura, Kaori Hoshi, Hiroshi Sakagami, Junko Nagai, Haixia Shi, Kenjiro Bandow
Publikováno v:
Anticancer Research. 40(1):87-95
Background/Aim: Very few studies are available about the biological activity of 3-styrylchromones. Our previous study demonstrated the importance of methoxy group at 6-position of the chromone ring and hydroxyl group at 4’-position of phenyl group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa98c12cdbfc7bd86c9c4932364e081
https://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-anticanres.13929
https://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-anticanres.13929
Autor:
Koichi Takao, Hiroshi Sakagami, Junko Nagai, Haixia Shi, Kenjiro Bandow, Nao Yoshida, Mineko Tomomura, Natsuko Sezaki, Yoshiaki Sugita, Akito Tomomura, Yoshihiro Uesawa
Publikováno v:
Anticancer Research. 39:6479-6488
BACKGROUND/AIM 4H-1-Benzopyran-4-one (chromone), present in various flavonoids as a backbone structure, has been used for the synthesis of anticancer drugs. The study aimed at investigating the cytotoxicity of eight 2-arylazolylchromones and twelve 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c873f50952c7c592918899592883cd
https://doi.org/10.21873/anticanres.13862
https://doi.org/10.21873/anticanres.13862
Autor:
Hiroshi Sakagami, Haixia Shi, Kenjiro Bandow, Mineko Tomomura, Akito Tomomura, Misaki Horiuchi, Tomohiro Fujisawa, Takaaki Oizumi
Publikováno v:
Molecules, Vol 23, Iss 8, p 1840 (2018)
Previous studies of the neuroprotective activity of polyphenols have used ununiform culture systems, making it difficult to compare their neuroprotective potency. We have established a new and simple method for preparing differentiated PC12 cells by
Externí odkaz:
https://doaj.org/article/c1c4890f3fe84127a7a62fb75e649bfd
Autor:
Mineko Tomomura, Ryuichiro Suzuki, Yoshiaki Shirataki, Hiroshi Sakagami, Nobuaki Tamura, Akito Tomomura
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130174 (2015)
Rhinacanthin C is a naphthoquinone ester with anti-inflammatory activity, found in Rhinacanthus nasutus (L) Kurz (Acanthaceae). We found that rhinacanthin C inhibited osteoclast differentiation stimulated by the receptor activator of nuclear factor-
Externí odkaz:
https://doaj.org/article/4e5d1489add24e62a82d8b9015b0cb7c
Autor:
Noriyuki Okudaira, Akito Tomomura, Kana Imanari, Hiroshi Sakagami, Yoshihiro Uesawa, Hidetsugu Wakabayashi, Kenjiro Bandow, Junko Nagai, Mineko Tomomura, Masashi Hashimoto
Publikováno v:
Anticancer Research. 39:3507-3518
Background/Aim: Very few studies of anticancer activity of azulene amides led us to investigate the cytotoxicity of 21 N-alkylazulene-1-carboxamides introduced either with 3-methyl [1-7], 7-isopropyl-3-methyl [8-14] or 2-methoxy group [15-21]. Materi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d29056ca62b8e299e26c36e688b7a3
https://doi.org/10.21873/anticanres.13497
https://doi.org/10.21873/anticanres.13497
Publikováno v:
Medicines
Medicines, Vol 8, Iss 41, p 41 (2021)
Medicines, Vol 8, Iss 41, p 41 (2021)
Blood calcium homeostasis is critical for biological function. Caldecrin, or chymotrypsin-like elastase, was originally identified in the pancreas as a serum calcium-decreasing factor. The serum calcium-decreasing activity of caldecrin requires the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28d7e85cdd9a4def02038114e2da44b
https://pubmed.ncbi.nlm.nih.gov/34436220
https://pubmed.ncbi.nlm.nih.gov/34436220
Publikováno v:
Biochemical and biophysical research communications. 523(4)
Caldecrin was previously isolated as a serum calcium-decreasing factor from the pancreas and is known to suppress receptor activator of nuclear factor-κB ligand (RANKL)-induced calcium oscillation pathways in osteoclasts. Here, we explored the effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d972e0677c6dbfcb2b1481229d745645
https://pubmed.ncbi.nlm.nih.gov/31973822
https://pubmed.ncbi.nlm.nih.gov/31973822
Autor:
Koichi Takao, Kenjiro Bandow, Yoshihiro Uesawa, Noriyuki Okudaira, Tsukasa Sakatsume, Hiroshi Sakagami, Haixia Shi, Yoshiaki Sugita, Junko Nagai, Mineko Tomomura, Akito Tomomura
Publikováno v:
Anticancer Research. 38:4459-4467
BACKGROUND/AIM 4H-1-Benzopyran-4-ones (chromones) provide a backbone structure for the chemical synthesis of potent anticancer drugs. In contrast to 2-(N-cyclicamino)chromones, the biological activity of 3-(N-cyclicamino)chromones has not been report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3384625198c25a523a9dce3ec65a209
https://doi.org/10.21873/anticanres.12748
https://doi.org/10.21873/anticanres.12748
Autor:
Yoshihiro Uesawa, Kenjiro Bandow, Noriyuki Okudaira, Haixia Shi, Yuka Kubota, Hiroshi Sakagami, Junko Nagai, Mineko Tomomura, Akito Tomomura, Koichi Takao, Yoshiaki Sugita
Publikováno v:
Anticancer Research. 38:4449-4457
BACKGROUND/AIM 4H-1-Benzopyran-4-one (chromone) provides a backbone structure for the chemical synthesis of potent anticancer drugs. Since studies of the biological activity of pyrano[4,3-b]chromones are limited, we investigated a total of 20 pyrano[
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01d0f4921e8ef52f4cbd96eda3406ad1
https://doi.org/10.21873/anticanres.12747
https://doi.org/10.21873/anticanres.12747