Characterization of phospholipid vesicles containing lauric acid: physicochemical basis for process and product development

Autor: Hernan Chaimovich, Rodrigo Villares Portugal, Luisa Barreiros, Paulo de Tarso Hennies, Gustavo P.B. Carretero, Marcela A. Segundo, Laura Farkuh, Cláudia Nunes, Cristiano L. P. Oliveira, Salette Reis, Shirley Schreier, Iolanda M. Cuccovia, Rodrigo Akira Muramoto, Alexandre Cassago, Pedro Leonidas Oseliero Filho

Publikováno v: Heliyon
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Heliyon, Vol 5, Iss 10, Pp e02648-(2019)

Lauric acid (LAH) strongly inhibits the growth of acne-causing bacteria. LAH is essentially water-insoluble and the solubility of laurate (LA) salts are medium and temperature dependent. Hence, LAH/LA preparations are difficult to formulate. Here we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94517ab17ec759f8cea327094c4f18cd
https://pubmed.ncbi.nlm.nih.gov/31720452

Basic and Clinical Studies of Fleroxacin on Infectious Enteritis

Autor: Hiroko SAGARA, Isao TOMIZAWA, Yoshihiko TAKIZAWA, Yoshiro NITTA, Takafumi TSUNODA, Tsuyoshi YAMAGUCHI, Gohta MASUDA, Masayoshi NEGISHI, Atsushi AJISAWA, Misako MURATA, Kenji OHNISHI, Shoichiro IRIMAJIRI, Yasuo MATSUOKA, Mitsuo OBANA, Fumio MATSUMOTO, Takeo IMAI, Fukiko AMANO, Chie NAKAMURA, Akira MURAMOTO, Hideyuki KANOH, Shiro HOSODA, Tadao BABA, Shinobu NAKAJO, Kunio YOSHIKAWA, Masao NAKAGAWA, Norimasa YASUDA, Young-Ki KIM, Mitsuru AKAO, Yoshihiro SAKAUE, Junko YAMADA, Hideki YOSHIDA, Yoshio KAWAGUCHI, Kazuya TAMURA, Masami MURAI, Tadakazu AISAKA, Fumiaki TSUKIYAMA, Motoko MIKAMI, Osamu KURIMURA, Ritsu TAMURA, Kousuke MIURA, Yatsuka IMAGAWA, Yoshio MATSUBARA, Makoto SAITO, Rintaro NAKAYA

Publikováno v: Journal of the Japanese Association for Infectious Diseases. 68:1390-1408

A clinical study was conducted on fleroxacin (FLRX) in 143 patients and carriers with infectious enteritis (shigellosis, Salmonella enteritis, Campylobacter enteritis, pathogenic Escherichia coli enteritis, Vibrio parahaemolyticus enteritis, cholera,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac6f760e927960c2325d299ace48110c
https://doi.org/10.11150/kansenshogakuzasshi1970.68.1390

Comparison of Clinical Efficacy of Rokitamycin (RKM) and Ofloxacin (OFLX) for the Treatment of Campylobacter Enteritis by a Double-Blind Method

Autor: Mitsuo OBANA, Isao TOMIZAWA, Yoshihiko TAKIZAWA, Yoshiro NITTA, Hiroko SAGARA, Takehisa SEO, Junichi SATO, Takafumi TSUNODA, Satomi OTA, Akira MACHII, Yoshitaka NAKAMURA, Teiko KATANO, Misako MURATA, Kenji OHNISHI, Tsuyoshi YAMAGUCHI, Gohta MASUDA, Masayoshi NEGISHI, Atsushi AJISAWA, Mitsuo KITAHARA, Keiko LEE, Shoichiro IRIMAJIRI, Yasuo MATSUOKA, Fumio MATSUMOTO, Takeo IMAI, Iwao SAKURAI, Takayuki TAKAHASHI, Fukiko AMANO, Akira MURAMOTO, Chie NAKAMURA, Hideyuki KANOU, Jun NARUSE, Yong-ki KIM, Yasuhiko INAMOTO, Mitsuru AKAO, Yoshihiro SAKAUE, Shiro HOSODA, Tadao BAMBA, Kenichi TATEWAKI, Kunio YOSHIKAWA, Iwao MATSUSHITA, Kenji FUSE, Masaya SASAKI, Kuniko KURISU, Masao NAKAGAWA, Katsuyuki KITOH, Toshio KAWAJIRI, Minoru KIZU, Takehiko SHIOMI, Sadao KATAOKA, Yoshio KAWAGUCHI, Akira FUKUMOTO, Kazuya TAMURA, Masami MURAI, Michio TANAKA, Osamu KURIMURA, Yoshio MATSUBARA, Makoto SAITO, Yatsuka IMAGAWA, Rintaro NAKAYA, Sankichi HORIUCHI, Yoshio INAGAKI

Publikováno v: Journal of the Japanese Association for Infectious Diseases. 65:1165-1182

The clinical efficacy, safety and usefulness of Rokitamycin (RKM), a new macrolide antibiotic, were compared with those of Ofloxacin (OFLX) for the treatment of Campylobacter enteritis by a double blind method. The daily dose level of RKM or OFLX was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e54c9cdd188b192f74928343998ea6e
https://doi.org/10.11150/kansenshogakuzasshi1970.65.1165

Clinical Trial of T-3262 on Acute Enteritis

Autor: Takakazu AOKI, Yoshio MATSUBARA, Hiroko SAGARA, Isao TOMIZAWA, Yoshihiko TAKIZAWA, Yoshirou NITTA, Takehisa SEO, Makoto KAMIMURA, Gohta MASUDA, Masayoshi NEGISHI, Shinten YO, Yatsuka IMAGAWA, Kenji OHNISHI, Kazue SAKU, Nagayo SHIMIZU, Tsuyoshi YAMAGUCHI, Masachika TSUJI, Jun-ichro HOSOYA, Jyuji HOSHINO, Fukiko AMANO, Chie NAKAMURA, Akira MURAMOTO, Yoshio KOBAYASHI, Ryuki KIN, Chihiro IMAI, Mitsuru AKAO, Akio TODO, Katsuhiko FUJIMI, Tadakazu AISAKA, Masanobu NIIMI, Toshiko MATSUO, Makoto SAITO, Rintaro NAKAYA, Nobuichi GOTO, Sankichi HORIUCHI, Yoshio INAGAKI, Hideko TAKANO

Publikováno v: Journal of the Japanese Association for Infectious Diseases. 63:593-605

For the purpose of evaluation of clinical efficacy, safety and usefulness on acute infectious enteritis (bacillary dysentery, and enteritis caused by Salmonella spp., Campylobacter spp., enteropathogenic E. coli, and so on), T-3262, a newly developed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32cca7359e454ed078485bac8cee6439
https://doi.org/10.11150/kansenshogakuzasshi1970.63.593

Comparison of Clinical Efficacy of Norfloxacin (NFLX) and Pipemidic Acid (PPA) in the Treatment of Infectious Enteritis by a Double-Blind Method

Autor: Takakazu AOKI, Nagayo SHIMIZU, Isao TOMIZAWA, Yoshihiko TAKIZAWA, Yoshio MATSUBARA, Takehisa SEO, Hiroko SAGARA, Keiko TAGAWA, Gohta MASUDA, Masayoshi NEGISHI, Chenden YOUNG, Yatsuka IMAGAWA, Misako MURATA, Tsuyoshi YAMAGUCHI, Masachika TSUJI, Jun-ichiro HOSOYA, Ippei FUJIMORI, Yoshio KOBAYASHI, Jyuji HOSHINO, Fukiko AMANO, Chie NAKAMURA, Akira MURAMOTO, Chihiro IMAI, Ryuki KIN, Mitsuru AKAO, Okisuke TSUNODA, Akio TODO, Katsuhiko FUJIMI, Akihiro HIRASA, Kan HASEGAWA, Tadakazu AISAKA, Masanobu NIIMI, Masao TAKEMOTO, Motoko MIKAMI, Toshiko MATSUO, Makoto SAITO, Rintaro NAKAYA, Nobuichi GOTO, Sankichi HORIUCHI, Noboru OKAMURA, Yoshio INAGAKI, Kayoko OZAWA, Yoshifumi TAKEDA

Publikováno v: Journal of the Japanese Association for Infectious Diseases. 61:830-848

The clinical efficacy, safety and usefulness of lomefloxacin (LFLX, NY-198), a new quinolone antimicrobial agent, were compared with those of pipemidic acid (PPA) in the treatment of infectious enteritis (bacillary dysentery, enteropathogenic Escheri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::88547121a029c186ed3b1b15834b50c6
https://doi.org/10.11150/kansenshogakuzasshi1970.61.830