Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Akira Yukita"'
Autor:
Yoshiaki Kondo, Rina Iwamoto, Takumi Takahashi, Kaito Suganuma, Hideaki Kato, Hiroaki Nakamura, Akira Yukita
Publikováno v:
Development, Growth & Differentiation. 65:16-22
The cortical bones of mammals, birds, and reptiles are composed of a complex of woven bone and lamellar bone (fibrolamellar bone) organized into a variety of different patterns; however, it remains unclear whether amphibians possess similar structure
Autor:
Kazutoshi Sayama, Akira Yukita, Takumi Takahashi, Tadashi Ninomiya, Hiroaki Nakamura, Tsuyoshi Koide, Yuji Imai, Rina Iwamoto, Kazuto Yoshimi, Miroku Hara
Publikováno v:
Journal of Bone and Mineral Metabolism. 39:558-571
Bone metabolism imbalances cause bone metabolism diseases, like osteoporosis, through aging. Although some chemokines are known to be involved in bone mass regulation, many have not been investigated. Thus, the present study aimed to investigate the
Publikováno v:
Journal of Oral Biosciences. 59:31-37
Objectives Dental pulp is composed of an odontoblastic layer, a subodontoblastic layer, and a central part. Although extracellular matrices affect the cells residing in these regions, the precise role of proteoglycans in dental pulp is incompletely u
Autor:
Akira Yukita
Publikováno v:
Journal of Oral Biosciences. 56:43-48
Background Bone morphogenetic proteins (BMPs) belong to the transforming growth factor-β (TGF-β) superfamily. BMPs can induce ectopic bone formation, and they play an important role in osteoblast differentiation. SUMOylation, which is a ubiquitin-l
Publikováno v:
Journal of Oral Biosciences. 54:43-47
Bone matrix consists of hydroxyapatite and organic components such as type I collagen and non-collagenous proteins. Extracellular matrices of bone tissue generally mean these organic components in bone matrix. However, a few extracellular matrices ar
Autor:
Akira Yukita, Tadashi Ninomiya, Hidehiro Ozawa, Hiroaki Nakamura, Akihiro Hosoya, Toru Hiraga
Publikováno v:
Journal of Histochemistry & Cytochemistry. 58:455-462
We elucidated the localization of Thy-1–positive cells in the perichondrium of fetal rat limb bones to clarify the distribution of osteogenic cells in the process of endochondral ossification. We also examined the formation of calcified bone-like m
Publikováno v:
Developmental Dynamics. 236:2757-2766
The small ubiquitin-related modifier (SUMO) is a member of the ubiquitin-like protein family, and SUMO conjugation (SUMOylation) resembles ubiquitination. Despite many SUMOylation target proteins being reported, the role of this system in vertebrate
Autor:
Kenji Sakurai, Akimasa Fukui, Hiroki Kobayashi, Makoto Asashima, Akira Yukita, Akira Kikuchi, Tatsuo Michiue, Hiroki Danno
Publikováno v:
Mechanisms of Development. 122(10):1138-1153
Wnt signaling pathways are essential in various developmental processes including differentiation, proliferation, cell migration, and cell polarity. Wnt proteins execute their multiple functions by activating distinct intracellular signaling cascades
Autor:
Akira Yukita, Kenji Sakurai, Akimasa Fukui, Akira Kikuchi, Tatsuo Michiue, Hideki Yamamoto, Makoto Asashima, Motomasa Ihara
Publikováno v:
Genes to Cells. 9:723-736
Small ubiqutin-related modifier (SUMO), which is responsible for the ubiquitination-like post-translational modification 'sumoylation', regulates a number of biological processes including, in particular, transcription. The rat protein Axam, which po
Autor:
Toshimasa Asahara, Hideki Yamamoto, Makoto Asashima, Akimasa Fukui, Toshiaki Suzuki, Keiji Tanaka, Takayuki Kadoya, Akira Kikuchi, Tatsuo Michiue, Akira Yukita
Publikováno v:
Molecular and Cellular Biology. 22:3803-3819
Axam has been identified as a novel Axin-binding protein that inhibits the Wnt signaling pathway. We studied the molecular mechanism by which Axam stimulates the downregulation of beta-catenin. The C-terminal region of Axam has an amino acid sequence