Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Akira Yamaji"'
Autor:
Masaki Sumi, Masatomo Sudo, Akira Yamaji, Nobuhito Shibata, Ikumi Iga, Keizo Fukushima, Hiroki Konishi, Tokuzo Minouchi
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 36:35-39
Micafungin (MCFG) is a novel echinocandin-class antifungal agent that extensively undergoes metabolic removal in the liver. In the present study, the influence of decreased blood volume on pharmacokinetic disposition of MCFG was examined using a rat
Autor:
Yutaka Eguchi, Masatomo Sudo, Takao Saotome, Akira Yamaji, Hiroki Konishi, Keizo Fukushima, Masaki Sumi, Ikumi Iga, Tetsu Hamamoto, Tokuzo Minouchi
Publikováno v:
Therapeutic Apheresis and Dialysis. 14:358-363
Change in the pharmacokinetic disposition of an antifungal agent micafungin (MCFG) by 8-hour plasma exchange (PE) with 3200 mL replacement was examined in a stem cell transplant recipient. On pharmacokinetic analysis of the time course of the serum c
Autor:
Keizo Fukushima, Kanji Takada, Tokuzo Minouchi, Masatomo Sudo, Akira Yamaji, Nobuhito Shibata, Hiroki Konishi, Masaki Sumi, Ikumi Iga
Publikováno v:
Fundamental & Clinical Pharmacology. 24:457-462
We examined whether the pharmacokinetic disposition of micafungin (MCFG), an echinocandin class antifungal agent, is altered in hyperbilirubinemia using a rat model prepared by bile duct ligation (BDL). Serum bilirubin levels were increased depending
Publikováno v:
Journal of Pharmacy Technology. 23:263-269
Background:Clinical usefulness of short-term education for long-term glycemic control has been unclear in patients with type 2 diabetes.Objective:To conduct a one week education program, incorporating a clinical path with group education and a team a
Publikováno v:
Journal of Pharmacy and Pharmacology. 56:477-483
We examined the effects of high-dose methylprednisolone (MP) on the disposition of ciclosporin (CsA) and hepatic microsomal CYP3A activity using rats. Methylprednisolone sodium succinate (MPS), a prodrug of MP, was intravenously administered as repea
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 68:1825-1830
The ability of various tea catechins to generate H2O2 and the hydroxyl radical in the presence of the Cu2+ ion was investigated and compared with the effect of iron ions. The presence of Cu2+ accelerated the generation of H2O2 by EGC, while EGCg with
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 29:495-500
In our hospital, the dosage form of phenytoin (DPH) was switched from hospital pharmacy-made 50% fine granules to commercial 10% powder. We surveyed the change in the serum DPH concentration in epileptic patients administered both DPH formulations, a
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 27:257-265
Summary Objectives: To formulate a simple equation for determining the daily dose requirements of digoxin by inclusion of creatinine clearance (Ccr) values as an explanatory variable. Methods: We included 235 routine monitoring and clinical laborator
Autor:
Shinji Tamaki, Tokuzo Minouchi, Hiroki Konishi, Masahiko Kinoshita, Akira Yamaji, Takayuki Nakatsuka, Michiaki Yoshida
Publikováno v:
Annals of Pharmacotherapy. 36:835-838
OBJECTIVE: To report a case showing patient noncompliance, supported by outcomes of pharmacokinetic analysis of theophylline as a surrogate drug. CASE SUMMARY: A 45-year-old woman with severe hypertension was treated with a variety of oral antihypert
Autor:
Fred Lembeck, Kunihiko Morita, Bernhard A. Peskar, Akira Yamaji, Victor A. Canfield, Ivo Juránek, B.A. Hennessy, Tokuzo Minouchi, F. Markos, Viktor Bauer, Ridwan Lin, Robert Levenson, Kyung Hwan Kim, Hye-Young Kim, M. Fitzpatrick, John F. O'Sullivan, Hiroki Konishi, H. M. Snow, Josef Donnerer, Jeong Yeon Seo
Publikováno v:
Pharmacology. 66:219-222