Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Akira Yamagata"'
Autor:
Takahito Ohshiro, Masamitsu Konno, Ayumu Asai, Yuki Komoto, Akira Yamagata, Yuichiro Doki, Hidetoshi Eguchi, Ken Ofusa, Masateru Taniguchi, Hideshi Ishii
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Epitranscriptomics is the study of RNA base modifications involving functionally relevant changes to the transcriptome. In recent years, epitranscriptomics has been an active area of research. However, a major issue has been the development
Externí odkaz:
https://doaj.org/article/fb68851eda5a4b55ad2abd1b0b484d75
Autor:
Akira Yamagata, Machiko Arita, Hiromasa Tachibana, Fumiaki Tokioka, Chikatoshi Sugimoto, Hiromitsu Sumikawa, Tomonori Tanaka, Hideki Yasui, Tomoyuki Fujisawa, Yutaro Nakamura, Takafumi Suda, Tadashi Ishida
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Idiopathic non-specific interstitial pneumonia (iNSIP), idiopathic pleuroparenchymal fibroelastosis (iPPFE), and unclassifiable idiopathic interstitial pneumonia (IIP) are IIPs with chronic fibrotic phenotypes, and unlike idiopath
Externí odkaz:
https://doaj.org/article/a4b90275b6a14434a456c0309a23672f
Autor:
Seigo Ito, Masahiro Nakashima, Takuya Ishikiriyama, Hiroyuki Nakashima, Akira Yamagata, Toshihiko Imakiire, Manabu Kinoshita, Shuhji Seki, Hiroo Kumagai, Naoki Oshima
Publikováno v:
Kidney & Blood Pressure Research (2022)
Introduction: In diabetic nephropathy (DN), mitochondrial dysfunction and leakage of mitochondrial DNA (mtDNA) are caused by the downregulation of superoxide dismutase 2 (SOD2). mtDNA induces the activation of Toll-like receptor (TLR) 9, which is pre
Externí odkaz:
https://doaj.org/article/b691784b03a8429bbec308459cdb1db0
Autor:
Masamitsu Konno, Jun Koseki, Ayumu Asai, Akira Yamagata, Teppei Shimamura, Daisuke Motooka, Daisuke Okuzaki, Koichi Kawamoto, Tsunekazu Mizushima, Hidetoshi Eguchi, Shuji Takiguchi, Taroh Satoh, Koshi Mimori, Takahiro Ochiya, Yuichiro Doki, Ken Ofusa, Masaki Mori, Hideshi Ishii
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
In cancer it is assumed that microRNAs recognise and regulate their targets uniformly. Here, the authors show that in gastrointestinal cancers methylation of microRNAs may impact their stability, and that levels of microRNA methylation are distinct i
Externí odkaz:
https://doaj.org/article/929c4fb0ae134cfbbe776b9545d3494b
Publikováno v:
Respiratory Medicine Case Reports, Vol 33, Iss , Pp 101440- (2021)
Small cell lung cancer (SCLC) transformation is a rare resistance mechanism to anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs), for which cytotoxic chemotherapy is often initiated. However, no case has been reported so far in which t
Externí odkaz:
https://doaj.org/article/5234e6fe334149d0a42d82491e03f7b2
Repeated administration of alpha-galactosylceramide ameliorates experimental lupus nephritis in mice
Autor:
Takahiro Uchida, Hiroyuki Nakashima, Akira Yamagata, Seigo Ito, Takuya Ishikiriyama, Masahiro Nakashima, Shuhji Seki, Hiroo Kumagai, Naoki Oshima
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Lupus nephritis is a crucial complication of systemic lupus erythematosus. In this study, we investigated the roles of mouse natural killer T (NKT) cells in lupus nephritis. From 24 weeks of age, NZB/NZW F1 mice were injected with alpha-gala
Externí odkaz:
https://doaj.org/article/ac99edb139cf49b3ad842ac3b0879ae8
Autor:
Akira Yamagata, Takahiro Uchida, Yuji Yamada, Takashi Nakanishi, Kazue Nagai, Toshihiko Imakiire, Naoki Oshima, Hiroo Kumagai
Publikováno v:
BMC Nephrology, Vol 18, Iss 1, Pp 1-4 (2017)
Abstract Background Amyloid A amyloidosis is one of the most common forms of amyloidosis. It is secondary to rheumatoid arthritis, which is difficult to manage and has a poor prognosis. We present a patient with rheumatoid arthritis and amyloid A amy
Externí odkaz:
https://doaj.org/article/172f42902fb24a24a475ffe0e217420b
Autor:
Shuhji Seki, Masahiro Nakashima, Hiroyuki Nakashima, Takuya Ishikiriyama, Hiroo Kumagai, Akira Yamagata, Naoki Oshima, Toshihiko Imakiire, Seigo Ito, Manabu Kinoshita
Publikováno v:
American Journal of Physiology-Renal Physiology. 321:F757-F770
We classified kidney macrophages (Mφs) into bone marrow-derived (BM-) macrophages expressing high CD11b and tissue-specific resident (Res-) macrophages expressing low CD11b. In diabetic nephropathy (DN) model mice, TLR9 expression and TNF-α product
Autor:
Tadashi Ishida, Machiko Arita, Keisuke Nishimura, Akira Yamagata, Tomohiro Yoshida, Ayaka Tanaka, Fumiaki Tokioka
Publikováno v:
Journal of Clinical Apheresis. 35:435-443
Background Patients with clinically amyopathic dermatomyositis (CADM) with anti-melanoma differentiation-associated gene 5 antibody (anti-MDA5 Ab) frequently develop rapidly progressive interstitial pneumonia (RPIP), often with fatal outcomes. Therap
Publikováno v:
Journal of Infection and Chemotherapy. 26:563-569
Background and objective Nursing and healthcare-associated pneumonia (NHCAP) is a category of healthcare-associated pneumonia modified for the healthcare system in Japan. To date, only a few studies have examined the prognostic factors of NHCAP in a