Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Akira Tanigami"'
Embryonic Stem Cells Form Articular Cartilage, not Teratomas, in Osteochondral Defects of Rat Joints
Autor:
Shigeyuki Wakitani, Hideyuki Aoki, Yasuji Harada, Masato Sonobe, Yusuke Morita, Ying Mu, Naohide Tomita, Yukio Nakamura, Satoshi Takeda, Takeshi K. Watanabe, Akira Tanigami
Publikováno v:
Cell Transplantation, Vol 13 (2004)
Embryonic stem (ES) cells are considered to be a potential tool for repairing articular cartilage defects, but so far it has been impossible to cause these cells to differentiate into chondrocytes exclusively, either in vivo or in vitro. To explore a
Externí odkaz:
https://doaj.org/article/36221951fca44d8fb28a645b815889ff
Autor:
James R. Hudson, Toshihisa Takagi, G. Mark Lathrop, M. T. Bihoreau, Peter N. Goodfellow, Haretsugu Hishigaki, Hiroumi Hayashi, Susanna L. Kiguwa, Atsushi B. Tsuji, Maria E. Davis, Yusuke Nakamura, Takeshi K. Watanabe, Angela L. Smith, Susanne Kiel, Akira Tanigami, Catherine Knights, Julie Browne, Toshihide Ono, Ricky Critcher, Patrick Huxtall, Michael R. James, Linda McCarthy, Caleb Webber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e1b22208c6768a4060668d029bf080
https://ora.ox.ac.uk/objects/uuid:51eee895-cdfe-44f5-9129-755452943b0a
https://ora.ox.ac.uk/objects/uuid:51eee895-cdfe-44f5-9129-755452943b0a
Publikováno v:
Journal of Orthopaedic Research. 26:10-17
The objective of this study was to evaluate the effects of the mechanical environment on the formation of cartilage tissue in transplanted embryonic stem (ES) cells. Full-thickness osteochondral defects were created on the patella groove of SD rats,
Autor:
Haretsugu Hishigaki, Hiroyuki Nakaya, Amu Kawaguchi, Yoshihiro Ohmori, Yutaka Suzuki, Shigeyuki Wakitani, Sumio Sugano, Takahiro Okabe, Akira Tanigami
Publikováno v:
Acta Orthopaedica. 78:687-692
The etiology of osteoarthritis (OA) is multifactorial and current research attributes it to a complex network of biochemical factors. We attempted to identify important molecules in OA joint destruction.Synovium was collected from 2 women with hip OA
Autor:
Tomoya O. Akama, Bruce Caterson, Andrew J. Quantock, Jun Nakayama, Keith M. Meek, Robert D. Young, Clare Elizabeth Hughes, Briedgeen Kerr, Nicola Beecher, Philip N. Lewis, Yasuo Tano, Yasutaka Hayashida, Michiko N. Fukada, Kohji Nishida, Akira Tanigami
Publikováno v:
Proceedings of the National Academy of Sciences. 103:13333-13338
Matrix assembly and homeostasis in collagen-rich tissues are mediated by interactions with proteoglycans (PGs) substituted with sulfated glycosaminoglycans (GAGs). The major GAG in cornea is keratan sulfate (KS), which is N-linked to one of three PG
Autor:
Toshihisa Takagi, Takeshi K. Watanabe, Akira Tanigami, Naohide Kanemoto, Atsushi B. Tsuji, Toshihide Ono, Keiko Oga, Yusuke Nakamura, Ayako Mizoguchi-Miyakita, Haretsugu Hishigaki, Yuki Yamasaki, Mikio Suzuki, Shiro Okuno, Shigeyuki Wakitani
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 32(5-6):355-366
SUMMARY 1. We have confirmed the Diabetes Mellitus OLETF type I (Dmo1) effect on hyperphagia, dyslipidaemia and obesity in the Otsuka Long-Evans Tokushima Fatty (OLETF) strain. The critical interval was narrowed down to 570 kb between D1Got258 to p16
Autor:
Kiyoshi Ooya, Hiroyuki Kumamoto, Yoshihiro Taniguchi, Akira Tanigami, Kenji Kimi, Kousuke Ohki, Mari Kondo
Publikováno v:
Journal of Oral Pathology and Medicine. 32:108-113
Background: Alterations of human patched (ptc) homolog have been proven to be responsible for basal cell nevus syndrome (BCNS). Mandibular cysts in heterozygous ptc knockout mouse (ptc+/− mouse) were microradiologically, histologically, immunohisto
Autor:
Kunio Takaoka, Shigeyuki Wakitani, T. Hattori, Akira Tanigami, N. Miyazawa, Satoshi Takeda, T. K. Watanabe, Tomoyuki Iwanaga
Publikováno v:
Rheumatology. 42:162-165
Objective. To determine whether the joint space is a suitable environment for embryonic stem (ES) cells to grow and form cartilage. Method. We transplanted ES cells into the knee joint and a subcutaneous space of mice with severe combined immunodefic
Publikováno v:
Biochemical and Biophysical Research Communications. 293:470-477
Murine OASIS is a putative CREB/ATF family transcription factor that is induced in gliosis, but its molecular role has not been determined. We have isolated the human OASIS gene and investigated the potential of OASIS protein as a transcriptional act
Autor:
Sawako Muroi, Munetomo Hida, Jun-ichi Imai, Kazuo Hanaoka, Akira Tanigami, Takami Komatsu, Yutaka Suzuki, Yoshitsugu Yamada, Sumio Sugano
Publikováno v:
DNA Sequence. 13:217-220
We isolated two mouse cDNA clones which show significant similarities with human angiotensin-converting enzyme-related carboxypeptidase (ACE2). The cDNAs were 2746 and 1995 bp in length and seemed to arise from the same gene by alternative splicing.