Zobrazeno 1 - 10
of 2 168
pro vyhledávání: '"Akira Tanaka"'
Autor:
Akira Tanaka, Hiroshi Nagabukuro, Kanako Kuniyeda, Haruhi Ando, Toshinori Higashi, Hirokazu Wakuda, Naoyuki Otani, Hideo Kudo, Masae Kuranari, Hidetoshi Furuie, Naoto Uemura
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 10, Pp n/a-n/a (2024)
Abstract Phosphodiesterase 4 (PDE4) inhibitor is associated with a broad‐spectrum anti‐inflammatory mechanism. However, securing clinically efficacious doses with sufficient safety margins remains challenging due to class specific adverse events
Externí odkaz:
https://doaj.org/article/24d23d8725c4495d92b860b2b6a4a0ad
Autor:
Akira Tanaka, Riki Okita, Takushi Morishige, Masanori Okada, Hidetoshi Inokawa, Katsutoshi Hirazawa, Kaori Kameyama, Akihiko Ikeda, Eiji Ikeda
Publikováno v:
Thoracic Cancer, Vol 15, Iss 4, Pp 353-357 (2024)
Abstract A 61‐year‐old woman, who had a history of total thyroidectomy for follicular variant of papillary thyroid carcinoma (PTC), visited our hospital for assessment of an enlarging nodule which appeared in the lung with multiple metastatic les
Externí odkaz:
https://doaj.org/article/4c0bd1e4cbc64b25a491265c62165403
Autor:
Akira Tanaka, Naoto Uemura, Kanako Kuniyeda, Haruhi Ando, Toshinori Higashi, Hiroshi Nagabukuro
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 10, Pp 1898-1910 (2023)
Abstract ART‐001 is an orally available selective PI3Kα inhibitor currently being developed for the treatment of slow‐flow vascular malformations (SFVMs). ART‐001 used to be developed for advanced solid tumors, but was suspended largely due to
Externí odkaz:
https://doaj.org/article/8ac6e765d6004e4698082031597390ac
Publikováno v:
Practical Laboratory Medicine, Vol 37, Iss , Pp e00337- (2023)
To investigate the regulation of soluble very low-density lipoprotein receptor (sVLDL-R), which is cleaved mostly from the extracellular domain of VLDL-R II, we generated two rat monoclonal antibodies (mAbs) against human sVLDL-R, and used them to de
Externí odkaz:
https://doaj.org/article/2fd0023dbc0f4a2e891a1a19cd0e504b
Publikováno v:
Heliyon, Vol 9, Iss 9, Pp e19632- (2023)
Background: Regarding changes in muscle mass, differences due to types of exercise and/or nutritional interventions, and associations with nutrient balances are still unclear. Methods: To estimate changes in muscle mass during a body weight loss prog
Externí odkaz:
https://doaj.org/article/3072b666abd848b08efcd93991e6fa69
Autor:
Yuma Horii, Shoichi Matsuda, Chikashi Toyota, Takumi Morinaga, Takeo Nakaya, Soken Tsuchiya, Masaki Ohmuraya, Takanori Hironaka, Ryo Yoshiki, Kotaro Kasai, Yuto Yamauchi, Noburo Takizawa, Akiomi Nagasaka, Akira Tanaka, Hidetaka Kosako, Michio Nakaya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Heart fibrosis involves a feedback loop where stiffening increases fibrosis-related gene expression in myofibroblasts. Here authors reveal the mechanosensitive nuclear translocation of VGLL3, where it phase separates and promotes collagen production,
Externí odkaz:
https://doaj.org/article/3d91cd5901fb4a358a83f06efa607833
Publikováno v:
IEEE Access, Vol 11, Pp 23227-23244 (2023)
Adversaries perform port scanning to discover accessible and vulnerable hosts as a prelude to cyber havoc. A darknet is a cyberattack observation network to capture these scanning activities through reachable yet unused IP addresses. However, the eno
Externí odkaz:
https://doaj.org/article/dd5a8edfaef64979b99fe4b0988b076c
Autor:
Michiko Matsuzawa Adachi, Katsuyuki Yoshida, Takahiko Fukuchi, Akira Tanaka, Naoto Yamamoto, Hitoshi Sugawara
Publikováno v:
Clinical Case Reports, Vol 11, Iss 6, Pp n/a-n/a (2023)
Key Clinical Message Poor personal hygiene wearing the same unwashed briefs, and prolonged sitting have led to the development of chronic perianal pyoderma. This can be confused with hidradenitis suppurativa and must be differentiated as their treatm
Externí odkaz:
https://doaj.org/article/2074bc298747491ca92bd84894d8c3bd
Autor:
Masahiro Umeda, Akira Tanaka, Tadaaki Kirita, Souichi Yanamoto, Kenichiro Uchida, Seiji Asoda, Koji Kawaguchi, Mitsunobu Otsuru, Yoshiko Yamamura, Takumi Hasegawa, Shin-ichi Yamada, Yasuyuki Michi, Toru Inomata, Hideki Nakayama, Takeshi Nomura, Jingo Kusukawa, Nobuhiro Yamakawa, On Hasegawa, Michihiro Ueda, Yoshimasa Kitagawa, Akimitsu Hiraki, Toshihiro Hasegawa, Yoichi Ohiro, Wataru Kobayashi, Takanori Kobayashi, Mitsuyoshi Iino, Masayuki Fukuda, Naomi Ishibashi-Kanno, Reona Aijima, Kazuma Noguchi, Masaya Okura, Tsuyoshi Sugiura, Yukari Shintani, Kazuhiro Yagihara, Masashi Yamashiro, Yoshihide Ota, Akihiro Miyazaki, Akinori Takeshita, Hitoshi Kawamata, Iwabuchi Hiroshi, Hiroshi Kurita
Publikováno v:
BMJ Open, Vol 12, Iss 9 (2022)
Introduction In early-stage oral tongue squamous cell carcinoma (OTSCC), elective neck dissection (END) is recommended when occult lymph node metastasis is suspected; however, there is no unanimous consensus on the risks and benefits of END in such c
Externí odkaz:
https://doaj.org/article/89e3ab15286b423db003c82d6abe4c52
Autor:
Kazumasa Iwamoto, Beverley Yamamoto, Isao Ohsawa, Daisuke Honda, Takahiko Horiuchi, Akira Tanaka, Atsushi Fukunaga, Junichi Maehara, Kouhei Yamashita, Tomoyuki Akita, Michihiro Hide
Publikováno v:
Allergology International, Vol 70, Iss 2, Pp 235-243 (2021)
Background: The rate at which patients are accurately diagnosed with hereditary angioedema (HAE), as well as diagnosed patients access to modern treatments differs greatly among countries. Moreover, the severity and burden of HAE on patients have bee
Externí odkaz:
https://doaj.org/article/e313e5de8b5848dd9fd3e3b88d292e59