Výsledky vyhledávání - "Akira Takaguri"

Akademický článek

Smoking-induced suppression of β-casein in milk is associated with an increase in miR-210-5p expression in mammary epithelia

Autor: Takeshi Chiba, Akira Takaguri, Toshiyasu Mikuma, Toshimi Kimura, Tomoji Maeda

Publikováno v: Biochemistry and Biophysics Reports, Vol 39, Iss , Pp 101773- (2024)

Smoking during lactation harmfully affects the amount and constituents of breast milk. Infants who consume breast milk containing miR-210-5p may have a higher risk of brain-related diseases. We investigated whether smoking during lactation decreases

Externí odkaz: https://doaj.org/article/1113752a80d546c683578dc4b2b3e734

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Akademický článek

Expression profiles of hsa-miR-148a-3p and hsa-miR-125b-5p in human breast milk and infant formulae

Autor: Takeshi Chiba, Aya Kooka, Kiyoko Kowatari, Megumi Yoshizawa, Naoko Chiba, Akira Takaguri, Yoshiyuki Fukushi, Fuminori Hongo, Hideki Sato, Shinichiro Wada

Publikováno v: International Breastfeeding Journal, Vol 17, Iss 1, Pp 1-9 (2022)

Abstract Background Milk-derived microRNAs (miRNAs), including hsa-miR-148a-3p (miR-148a) and hsa-miR-125b-5p (miR-125b), have been shown to be beneficial to the gastrointestinal function in infants. Here, we investigated their expression during lact

Externí odkaz: https://doaj.org/article/ab19b35de087404582ce6f59ba34940a

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Akademický článek

Inhibition of the TNF-α–Induced Serine Phosphorylation of IRS-1 at 636/639 by AICAR

Autor: Tomohito Shibata, Akira Takaguri, Kazuo Ichihara, Kumi Satoh

Publikováno v: Journal of Pharmacological Sciences, Vol 122, Iss 2, Pp 93-102 (2013)

AMP-activated protein kinase (AMPK) contributes to the acceleration of insulin signaling. However, the mechanism by which AMPK regulates insulin signaling remains unclear. Serine phosphorylation of insulin receptor substrate (IRS)-1 negatively regula

Externí odkaz: https://doaj.org/article/9795fceec6c24583b90d51d219dd1ae2

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Akademický článek

Possible Mechanisms Underlying Statin-Induced Skeletal Muscle Toxicity in L6 Fibroblasts and in Rats

Autor: Mai Itagaki, Akira Takaguri, Seiichiro Kano, Shigeru Kaneta, Kazuo Ichihara, Kumi Satoh

Publikováno v: Journal of Pharmacological Sciences, Vol 109, Iss 1, Pp 94-101 (2009)

3-Hydroxy-3-methylglutaryl CoA reductase inhibitors (statins) are safe and well-tolerated therapeutic drugs. However, they occasionally induce myotoxicity such as myopathy and rhabdomyolysis. Here, we investigated the mechanism of statin-induced myot

Externí odkaz: https://doaj.org/article/e79b97ee26644adf8c117e5dc67461df

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Akademický článek

Effects of Rosuvastatin and Pitavastatin on Ischemia-Induced Myocardial Stunning in Dogs

Autor: Kumi Satoh, Akira Takaguri, Mai Itagaki, Seiichiro Kano, Kazuo Ichihara

Publikováno v: Journal of Pharmacological Sciences, Vol 106, Iss 4, Pp 593-599 (2008)

Incomplete recovery of myocardial contraction after reperfusion following brief ischemia is called the “stunning phenomenon” in an animal experiment. A hydrophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin) does

Externí odkaz: https://doaj.org/article/a8646e886d044e688f37584bbe7f73f5

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Akademický článek

Effects of Atorvastatin and Pravastatin on Signal Transduction Related to Glucose Uptake in 3T3L1 Adipocytes

Autor: Akira Takaguri, Kumi Satoh, Mai Itagaki, Yukiko Tokumitsu, Kazuo Ichihara

Publikováno v: Journal of Pharmacological Sciences, Vol 107, Iss 1, Pp 80-89 (2008)

A number of patients with hyperlipidemia are prescribed 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors that are concomitantly used along with the treatment of diabetes mellitus. The effects of atorvastatin and pravastatin on insulin-induced gluc

Externí odkaz: https://doaj.org/article/07f332147d5f4e5fbf1188a047b136e0

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