Zobrazeno 1 - 10
of 546
pro vyhledávání: '"Akira Sugawara"'
Publikováno v:
Epilepsia Open, Vol 9, Iss 1, Pp 200-209 (2024)
Abstract Objective Managing the risk of epileptic seizures in older adults is increasingly important as the population ages. Leukotriene receptor antagonists (LTRAs) are commonly used to treat asthma or allergic rhinitis. Preclinical studies suggest
Externí odkaz:
https://doaj.org/article/50397e84f1be48c98e8067b5d02439c4
Autor:
Eiji Nakatani, Hiromitsu Ohno, Tatsunori Satoh, Daito Funaki, Chikara Ueki, Taku Matsunaga, Takayoshi Nagahama, Toru Tonoike, Hiromichi Yui, Akinori Miyakoshi, Yoshihiro Tanaka, Ataru Igarashi, Hiraku Kumamaru, Nagato Kuriyama, Akira Sugawara
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0308734 (2024)
BackgroundWestern guidelines often recommend biguanides as the first-line treatment for diabetes. However, dipeptidyl peptidase-4 (DPP-4) inhibitors, alongside biguanides, are increasingly used as the first-line therapy for type 2 diabetes (T2DM) in
Externí odkaz:
https://doaj.org/article/a5e9436f17aa4c0181bb802b4c9559f5
Autor:
Yu Soma, Masaaki Murakami, Eiji Nakatani, Yoko Sato, Satoshi Tanaka, Kiyoshi Mori, Akira Sugawara
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Some hemodialysis patients are not suitable for creation of an arteriovenous fistula (AVF) or arteriovenous graft (AVG). However, they can receive a tunneled cuffed central venous catheter (tcCVC), but this carries risks of infection and mor
Externí odkaz:
https://doaj.org/article/609c97baf00f43c4bce949f50b21380e
Autor:
Shin Ito, Aya Hashimoto, Kazunori Yamaguchi, Sadafumi Kawamura, Shingo Myoen, Maki Ogawa, Ikuro Sato, Takamichi Minato, Shingo Miyabe, Akira Nakazato, Keitaro Fujii, Mai Mochizuki, Haruna Fujimori, Keiichi Tamai, Tetsuya Niihori, Yoko Aoki, Akira Sugawara, Hironobu Sasano, Hiroshi Shima, Jun Yasuda
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 10, Iss 3, Pp n/a-n/a (2022)
Abstract Carney complex (CNC) is a rare hereditary syndrome that involves endocrine dysfunction and the development of various types of tumors. Chromosome 2p16 and PRKAR1A on chromosome 17 are known susceptibility loci for CNC. Here we report a mothe
Externí odkaz:
https://doaj.org/article/5c026882ca754c859701f339f3e86dfd
Autor:
Yohei Doi, Kenichi Koga, Sayaka Sugioka, Yui Inoue, Tetsuya Arisato, Keisuke Nishioka, Takeshi Ishihara, Akira Sugawara
Publikováno v:
Nefrología, Vol 41, Iss 3, Pp 356-358 (2021)
Externí odkaz:
https://doaj.org/article/37abb20e9b72439bb2760de073f1a38e
Autor:
Hiroki Shimada, Shuko Hata, Yuto Yamazaki, Yuri Otsubo, Ikuko Sato, Kazue Ise, Atsushi Yokoyama, Takashi Suzuki, Hironobu Sasano, Akira Sugawara, Yasuhiro Nakamura
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12803 (2022)
Primary aldosteronism (PA) is considered the most common form of secondary hypertension, which is associated with excessive aldosterone secretion in the adrenal cortex. The cause of excessive aldosterone secretion is the induction of aldosterone synt
Externí odkaz:
https://doaj.org/article/46472a62d4ad4ba29c9cf2fadd8059e1
Autor:
Hiroki Shimada, Naotaka Kogure, Erika Noro, Masataka Kudo, Kaori Sugawara, Ikuko Sato, Kyoko Shimizu, Makoto Kobayashi, Dai Suzuki, Rehana Parvin, Takako Saito‐Ito, Akira Uruno, Akiko Saito‐Hakoda, William E. Rainey, Sadayoshi Ito, Atsushi Yokoyama, Akira Sugawara
Publikováno v:
FEBS Open Bio, Vol 7, Iss 9, Pp 1410-1421 (2017)
Aldosterone synthase is the key rate‐limiting enzyme in adrenal aldosterone production, and induction of its gene (CYP11B2) results in the progression of hypertension. As hypertension is a frequent complication among patients with diabetes, we set
Externí odkaz:
https://doaj.org/article/2ae9d397d3764417a027e9cbb10c10b1
Autor:
Yui Inoue, Yohei Doi, Tetsuya Arisato, Sayaka Sugioka, Kenichi Koga, Keisuke Nishioka, Akira Sugawara
Publikováno v:
Kidney International Reports, Vol 2, Iss 5, Pp 984-987 (2017)
Externí odkaz:
https://doaj.org/article/ac56493f474348148e0f56d8c3d68237
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 892 (2021)
The adrenal cortex produces steroid hormones as adrenocortical hormones in the body, secreting mineralocorticoids, glucocorticoids, and adrenal androgens, which are all considered essential for life. Adrenocortical tumors harbor divergent hormonal ac
Externí odkaz:
https://doaj.org/article/117541bb17f34c669da0adc47feea0df
Deletion of CD38 Suppresses Glial Activation and Neuroinflammation in a Mouse Model of Demyelination
Autor:
Jureepon Roboon, Tsuyoshi Hattori, Hiroshi Ishii, Mika Takarada-Iemata, Thuong Manh Le, Yoshitake Shiraishi, Noriyuki Ozaki, Yasuhiko Yamamoto, Akira Sugawara, Hiroshi Okamoto, Haruhiro Higashida, Yasuko Kitao, Osamu Hori
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
CD38 is an enzyme that catalyzes the synthesis of cyclic adenosine diphosphate-ribose from nicotinamide adenine dinucleotide (NAD+). We recently reported that this molecule regulates the maturation and differentiation of glial cells such as astrocyte
Externí odkaz:
https://doaj.org/article/8fb8f4986ca847c79eade557193a3dfa