Zobrazeno 1 - 10
of 318
pro vyhledávání: '"Akira Shinohara"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract DNA double-strand breaks (DSBs) activate DNA damage responses (DDRs) in both mitotic and meiotic cells. A single-stranded DNA (ssDNA) binding protein, Replication protein-A (RPA) binds to the ssDNA formed at DSBs to activate ATR/Mec1 kinase
Externí odkaz:
https://doaj.org/article/d310ebb9c6f748008ddb19aab92287db
Autor:
Daigo Arimura, Akira Shinohara, Shunsuke Katsumi, Shintaro Obata, Taku Ikegami, Naomu Sawada, Keiichiro Mori, Mitsuru Saito
Publikováno v:
Frontiers in Surgery, Vol 11 (2024)
Trans-sacral canal plasty (TSCP) is a minimally invasive lumbar spine surgery under local anaesthesia. TSCP is expected to be effective regardless of whether the patient has had previous surgery. However, there are cases in which open revision surger
Externí odkaz:
https://doaj.org/article/17f8a880be764a74890b220fc998436c
Autor:
Masaru Ito, Asako Furukohri, Kenichiro Matsuzaki, Yurika Fujita, Atsushi Toyoda, Akira Shinohara
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The formation of RAD51/DMC1 filaments on single-stranded (ss)DNAs essential for homology search and strand exchange in DNA double-strand break (DSB) repair is tightly regulated. FIGNL1 AAA+++ ATPase controls RAD51-mediated recombination in h
Externí odkaz:
https://doaj.org/article/e1790d02b8df41b7822952d6cc753b45
Autor:
Shunsuke Katsumi, Akira Shinohara, Daigo Arimura, Shintaro Obata, Taku Ikegami, Mitsuru Saito
Publikováno v:
Spine Surgery and Related Research, Vol 7, Iss 5, Pp 458-460 (2023)
Externí odkaz:
https://doaj.org/article/e44db4f0945f49aeba2b56a7db1f9f4d
Autor:
Takeshi Sato, Akira Shinohara
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102454- (2023)
Summary: In membrane proteins, a transmembrane region and a juxtamembrane region play important roles in its function. Here, we present a protocol for characterizing membrane protein dynamics between the juxtamembrane region of the single transmembra
Externí odkaz:
https://doaj.org/article/4904d321d6bb47b5ae8d03a9bfc3c88c
Autor:
Shota Katayama, Chikara Ushiku, Taku Ikegami, Takeshi Inoue, Akira Shinohara, Takayoshi Kajiwara, Daigo Arimura, Shoshi Akiyama, Shunsuke Katsumi, Shintaro Obata, Shigeru Soshi, Mitsuru Saito
Publikováno v:
Spine Surgery and Related Research, Vol 6, Iss 5, Pp 569-572 (2022)
Externí odkaz:
https://doaj.org/article/49066e2ad69e45ecb023a893bedded1b
Autor:
Miki Shinohara, Akira Shinohara
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Meiotic crossing over is essential for the segregation of homologous chromosomes. The formation and distribution of meiotic crossovers (COs), which are initiated by the formation of double-strand break (DSB), are tightly regulated to ensure at least
Externí odkaz:
https://doaj.org/article/26963328249d4da9af878f6546539d08
Autor:
Daisuke Ueki, Shinya Suzuki, Takahiro Ohta, Akira Shinohara, Yasukata Ohashi, Daisuke Konuma, Yasuaki Ryushima, Ryoko Udagawa, Hironori Motoshige, Masahiro Ieoka, Akihiro Taji, Yuuki Kogure, Mikako Hiraike, Miyuki Uoi, Kazuhiko Ino, Toshikatsu Kawasaki, Masakazu Yamaguchi
Publikováno v:
Pharmacy, Vol 12, Iss 1, p 1 (2023)
Although prescription review is an important role for pharmacists in anticancer drug therapy, there are no guidelines in Japan that specify what pharmacists should check for in chemotherapy regimens. This prospective multicenter survey aimed to inves
Externí odkaz:
https://doaj.org/article/affda06035f2417e91f2adfbc852a57e
Autor:
Michael Gioia, Lisette Payero, Sagar Salim, Ghanim Fajish V, Amamah F Farnaz, Gianno Pannafino, Jun Jie Chen, V P Ajith, Sherikat Momoh, Michelle Scotland, Vandana Raghavan, Carol M Manhart, Akira Shinohara, K T Nishant, Eric Alani
Publikováno v:
PLoS Biology, Vol 21, Iss 4, p e3002085 (2023)
In most sexually reproducing organisms crossing over between chromosome homologs during meiosis is essential to produce haploid gametes. Most crossovers that form in meiosis in budding yeast result from the biased resolution of double Holliday juncti
Externí odkaz:
https://doaj.org/article/3680fb05ae2f4d129bc48b9b31b5ced0
Autor:
Masaru Ito, Akira Shinohara
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Meiocytes organize higher-order chromosome structures comprising arrays of chromatin loops organized at their bases by linear axes. As meiotic prophase progresses, the axes of homologous chromosomes align and synapse along their lengths to form ladde
Externí odkaz:
https://doaj.org/article/4b8c45a3c4c04c488f8761554dd5311b