Zobrazeno 1 - 10
of 392
pro vyhledávání: '"Akira Shimamoto"'
Autor:
Yuki Yamamoto, Ryou-u Takahashi, Masaki Kinehara, Kimiyoshi Yano, Tatsuya Kuramoto, Akira Shimamoto, Hidetoshi Tahara
Publikováno v:
Genes, Vol 15, Iss 5, p 543 (2024)
Cellular senescence is an irreversible growth arrest that acts as a barrier to cancer initiation and progression. Histone alteration is one of the major events during replicative senescence. However, little is known about the function of H3.3 in cell
Externí odkaz:
https://doaj.org/article/6913d6121c284a4895cd746f405cad73
Autor:
Yutaka Toyomasu, Kenta Matsui, Kazuki Omori, Akinori Takada, Kyoko Imanaka‐Yoshida, Isao Tawara, Akira Shimamoto, Motoshi Takao, Hiroyasu Kobayashi, Atsushi Tomaru, Hajime Fujimoto, Tetsu Kobayashi, Haiime Sakuma, Yoshihito Nomoto
Publikováno v:
Thoracic Cancer, Vol 13, Iss 20, Pp 2904-2907 (2022)
Abstract Radiation‐induced lung damage (RILD) is a critical problem in lung cancer radiotherapy, and it is difficult to predict its severity. Although no biomarkers for RILD have been established, tenascin C (TNC) is an extracellular matrix glycopr
Externí odkaz:
https://doaj.org/article/7ecba493802b4aa09259857a7537e90a
Autor:
Kunihiro Asanuma, Masaya Tsujii, Tomohito Hagi, Tomoki Nakamura, Kouji Kita, Akira Shimamoto, Takeshi Kataoka, Motoshi Takao, Akihiro Sudo
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundChest wall malignant tumor (including primary and metastatic lesions) is rare, representing less than 5% of all thoracic malignancies. Local control of chest wall malignancies requires wide resection with tumor-free margins. These requireme
Externí odkaz:
https://doaj.org/article/a69e6ebc07074ed19504a551b591e4a3
Autor:
Toshiya Funatsuki, Haruhiko Ogata, Hidetoshi Tahara, Akira Shimamoto, Yoshiteru Takekita, Yosuke Koshikawa, Shinpei Nonen, Koichiro Higasa, Toshihiko Kinoshita, Masaki Kato
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12199 (2023)
Individual treatment outcomes to antidepressants varies widely, yet the determinants to this difference remain elusive. MicroRNA (miRNA) gene expression regulation in major depressive disorder (MDD) has attracted interest as a biomarker. This 4-week
Externí odkaz:
https://doaj.org/article/27436630a6f74d8f95ad48de7873c4ae
Autor:
Atsushi Ito, Daisuke Yamaguchi, Shinji Kaneda, Koji Kawaguchi, Akira Shimamoto, Makiko Kubooka, Yoshihito Nomoto, Motoshi Takao
Publikováno v:
World Journal of Surgical Oncology, Vol 19, Iss 1, Pp 1-5 (2021)
Abstract Background Endobronchial metastasis is a very rare type of recurrence after lung cancer surgery. Surgical intervention may be difficult to perform due to the postoperative reduction in the activities of daily living (ADL) and the invasivenes
Externí odkaz:
https://doaj.org/article/8f46a6e280dd4cdf88aac13a6f2a6faa
Autor:
Kyoshiro Tsuge, Akira Shimamoto
Publikováno v:
Genes, Vol 13, Iss 10, p 1802 (2022)
A rare and autosomal recessive premature aging disorder, Werner syndrome (WS) is characterized by the early onset of aging-associated diseases, including shortening stature, alopecia, bilateral cataracts, skin ulcers, diabetes, osteoporosis, arterios
Externí odkaz:
https://doaj.org/article/e6ea0fe2fdf5474b889ed550ce3db176
Autor:
Hisaya Kato, Yoshiro Maezawa, Yasuo Ouchi, Naoya Takayama, Masamitsu Sone, Kanako Sone, Aki Takada-Watanabe, Kyoko Tsujimura, Masaya Koshizaka, Sayaka Nagasawa, Hisako Saitoh, Manami Ohtaka, Mahito Nakanishi, Hidetoshi Tahara, Akira Shimamoto, Atsushi Iwama, Koji Eto, Koutaro Yokote
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102360- (2021)
Adult progeria Werner syndrome (WS), a rare autosomal recessive disorder, is characterized by accelerated aging symptoms after puberty. The causative gene, WRN, is a member of the RecQ DNA helicase family and is predominantly involved in DNA replicat
Externí odkaz:
https://doaj.org/article/6287b5f3d3414ecf8b91e3511ecf13b2
Autor:
Masaki Kato, Haruhiko Ogata, Hidetoshi Tahara, Akira Shimamoto, Yoshiteru Takekita, Yosuke Koshikawa, Keiichiro Nishida, Shinpei Nonen, Koichiro Higasa, Toshihiko Kinoshita
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3873 (2022)
Major depressive disorder (MDD) is a life-impairing disorder, and early successful treatment is important for a favorable prognosis. However, early response to antidepressants differs widely among individuals, and is difficult to predict pre-treatmen
Externí odkaz:
https://doaj.org/article/ce261a99fa2645b5874caea8e2fbc766
Autor:
Tomohisa Nezu, Naohisa Hosomi, Tetsuya Takahashi, Kumiko Anno, Shiro Aoki, Akira Shimamoto, Hirofumi Maruyama, Tomonori Hayashi, Masayasu Matsumoto, Hidetoshi Tahara
Publikováno v:
EBioMedicine, Vol 2, Iss 8, Pp 960-967 (2015)
Background: The telomeric 3′-overhang (G-tail) length is essential for the biological effects of telomere dysfunction in vitro, but the association of length with aging and cardiovascular risk is unclear in humans. We investigated the association b
Externí odkaz:
https://doaj.org/article/6f03ae561473454cb8ace8a5a4f280cf
Autor:
Shinji Kotaka, Shigeyuki Wakitani, Akira Shimamoto, Naosuke Kamei, Mikiya Sawa, Nobuo Adachi, Mituo Ochi
Publikováno v:
Stem Cells International, Vol 2017 (2017)
Cartilage regeneration treatments using stem cells are associated with problems due to the cell source and the difficulty of delivering the cells to the cartilage defect. We consider labeled induced pluripotent stem (iPS) cells to be an ideal source
Externí odkaz:
https://doaj.org/article/fb208934065c4497acd1e023fc2b42cb