Zobrazeno 1 - 10
of 470
pro vyhledávání: '"Akira Sakurai"'
Publikováno v:
IEEE Access, Vol 12, Pp 80559-80578 (2024)
The blockchain trilemma, introduced in 2017 on a blog post authored by Vitalik Buterin, one of Ethereum’s co-founders, asserts that achieving decentralization, scalability, and security simultaneously within a blockchain is unattainable. While this
Externí odkaz:
https://doaj.org/article/394abfdf9b774a2993b6a7c66794585c
Publikováno v:
Brain Sciences, Vol 14, Iss 5, p 468 (2024)
We present a novel set of quantitative measures for “likeness” (error function) designed to alleviate the time-consuming and subjective nature of manually comparing biological recordings from electrophysiological experiments with the outcomes of
Externí odkaz:
https://doaj.org/article/f54f7f001840494cbbaf634e07eafe43
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14638 (2023)
Temperature sensation involves thermosensitive TRP (thermoTRP) and non-TRP channels. Drosophila larval Class III (CIII) neurons serve as the primary cold nociceptors and express a suite of thermoTRP channels implicated in noxious cold sensation. How
Externí odkaz:
https://doaj.org/article/0b7cc4a31cd943868d9aaab4fbec8541
Autor:
Nathaniel J Himmel, Akira Sakurai, Atit A Patel, Shatabdi Bhattacharjee, Jamin M Letcher, Maggie N Benson, Thomas R Gray, Gennady S Cymbalyuk, Daniel N Cox
Publikováno v:
eLife, Vol 12 (2023)
Individual sensory neurons can be tuned to many stimuli, each driving unique, stimulus-relevant behaviors, and the ability of multimodal nociceptor neurons to discriminate between potentially harmful and innocuous stimuli is broadly important for org
Externí odkaz:
https://doaj.org/article/e32c5f41121d4fd2a631351366842372
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101510- (2022)
Summary: Here, we outline protocols to study cold acclimation in Drosophila from a neurobiological perspective, starting with fictive cold acclimation using a custom-built optogenetics-housing apparatus we call the OptoBox. We also provide detailed s
Externí odkaz:
https://doaj.org/article/2b4726ec2d83490e80e415c2586181ad
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Calcium (Ca2+) plays a pivotal role in modulating neuronal-mediated responses to modality-specific sensory stimuli. Recent studies in Drosophila reveal class III (CIII) multidendritic (md) sensory neurons function as multimodal sensors regulating dis
Externí odkaz:
https://doaj.org/article/041e5e2f4b394e718aadcd0920267572
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Coding noxious cold signals, such as the magnitude and rate of temperature change, play essential roles in the survival of organisms. We combined electrophysiological and computational neuroscience methods to investigate the neural dynamics of Drosop
Externí odkaz:
https://doaj.org/article/3f49ba1595c2460bb003f4bfb775bdf0
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Gastropod mollusks are known for their large, individually identifiable neurons, which are amenable to long-term intracellular recordings that can be repeated from animal to animal. The constancy of individual neurons can help distinguish state-depen
Externí odkaz:
https://doaj.org/article/e3d2b92b6032489db2e1b79958ab12e1
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Short-term synaptic plasticity is a fast and robust modification in neuronal presynaptic output that can enhance release strength to drive facilitation or diminish it to promote depression. The mechanisms that determine whether neurons displ
Externí odkaz:
https://doaj.org/article/0169aea43b4549faa17ab3ee1c7c007e
Autor:
Nathaniel J. Himmel, Jamin M. Letcher, Akira Sakurai, Thomas R. Gray, Maggie N. Benson, Kevin J. Donaldson, Daniel N. Cox
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102657- (2021)
Summary: Low temperatures can be fatal to insects, but many species have evolved the ability to cold acclimate, thereby increasing their cold tolerance. It has been previously shown that Drosophila melanogaster larvae perform cold-evoked behaviors un
Externí odkaz:
https://doaj.org/article/4878e8a0188a43a797fcdb81156710cd