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of 6
pro vyhledávání: '"Akira Saikawa"'
Autor:
Nobuhiro Tanabe, Akira Saikawa, Toshiyuki Sunaya, Takeshi Ogo, Toshiaki Sakaguchi, Masaru Hatano, Yoichi Tazaki
Publikováno v:
Pulmonary hypertension.
Background: Riociguat is approved in Japan for treatment of pulmonary arterial hypertension and inoperable or persistent/recurrent CTEPH after pulmonary endarterectomy. Aim: Obtain post-marketing information on riociguat safety in treatment of CTEPH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed99c99774d29f2ab2e612b2037648b3
https://doi.org/10.1183/13993003.congress-2018.pa3054
https://doi.org/10.1183/13993003.congress-2018.pa3054
Publikováno v:
Journal of Controlled Release. 40:269-276
Release of leuprorelin, an LHRH agonist, from injectable microcapsules and degradation of its biodegradable polymer [( d,l -lactic-glycolic) acid copolymer: PLGA] matrix were investigated to optimize an in vitro release test system and to clarify the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69f4ad84416d098ff52b1a867a94f625
https://doi.org/10.1016/0168-3659(95)00194-8
https://doi.org/10.1016/0168-3659(95)00194-8
Autor:
Yoshinobu Takakura, Fumiyoshi Yamashita, Hitoshi Sezaki, Takehiko Nomura, Akira Saikawa, Mitsuru Hashida
Publikováno v:
Pharmaceutical Research. 13:1438-1444
Purpose. The purpose of this study was to establish an experimental system for evaluation of the intratumoral behavior of drugs after intratumoral injection using perfused tissue-isolated tumor preparations of Walker 256 carcinoma (3.46–9.73g, n =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a39bf5f5a70c52e6c73477a5582ffa02
https://doi.org/10.1023/a:1016054807555
https://doi.org/10.1023/a:1016054807555
Publikováno v:
Chemical and Pharmaceutical Bulletin. 40:737-740
[3H]Water and [14C]inulin were injected into perfused rabbit muscle with or without hyaluronidase (300 units/ml) and their absorption into venous effluent from muscle was determined. Hyaluronidase accelerated the absorption of both compounds but the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baeaf358b5f059294b4e8780a9de2e43
https://doi.org/10.1248/cpb.40.737
https://doi.org/10.1248/cpb.40.737
Autor:
Kazuo Honda, Akira Saikawa, Toshiyuki Sakaeda, Satoko Morita, Yoshinobu Takakura, Mitsuru Hashida, Fumiyoshi Yamashita, Takehiko Nomura
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 52(3)
The pharmacokinetics and therapeutic effects of macromolecular prodrugs of mitomycin C (MMC), MMC-dextran conjugates (MMC-D) were studied after intratumoural injection in rats bearing Walker 256 carcinosarcoma. As the first step, the intratumoural di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d33e76ede30e98340f601ac3713ba86
https://pubmed.ncbi.nlm.nih.gov/9743445
https://pubmed.ncbi.nlm.nih.gov/9743445
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