Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Akira Ootsuyama"'
Autor:
Masaoki Kohzaki, Akira Ootsuyama, Toshiaki Abe, Manabu Tsukamoto, Toshiyuki Umata, Ryuji Okazaki
Publikováno v:
JBMR Plus, Vol 6, Iss 12, Pp n/a-n/a (2022)
ABSTRACT Ionizing radiation (IR) is a well‐known carcinogen. High‐dose‐rate (HDR) IR is known to damage long bones (in terms of mass and structure), but the relationships among dose rates (particularly low‐dose‐rate [LDR] IR), long‐bone c
Externí odkaz:
https://doaj.org/article/8bfe6fd3ebf5401a8d1646a758b04156
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Tumor suppressor genes are involved in maintaining genome integrity during reproduction (e.g., meiosis). Thus, deleterious alleles in tumor suppressor-deficient mice would exhibit higher mortality during the perinatal period. A recent aging
Externí odkaz:
https://doaj.org/article/ae51f3e286524bcbacde0b1bd96086a3
Autor:
Lili Cao, Hidehiko Kawai, Megumi Sasatani, Daisuke Iizuka, Yuji Masuda, Toshiya Inaba, Keiji Suzuki, Akira Ootsuyama, Toshiyuki Umata, Kenji Kamiya, Fumio Suzuki
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104279 (2014)
Different levels or types of DNA damage activate distinct signaling pathways that elicit various cellular responses, including cell-cycle arrest, DNA repair, senescence, and apoptosis. Whereas a range of DNA-damage responses have been characterized,
Externí odkaz:
https://doaj.org/article/4fc503789a634d4e9abf1730f60ae876
Autor:
Yoshitaka Yamaguchi, Hironori Miyata, Keiji Uchiyama, Akira Ootsuyama, Sachiko Inubushi, Tsuyoshi Mori, Naomi Muramatsu, Shigeru Katamine, Suehiro Sakaguchi
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43540 (2012)
Accumulating lines of evidence indicate that the N-terminal domain of prion protein (PrP) is involved in prion susceptibility in mice. In this study, to investigate the role of the octapeptide repeat (OR) region alone in the N-terminal domain for the
Externí odkaz:
https://doaj.org/article/5c0e4125325b43cc8a25daa52393a9e4
Understanding the biological effects of low-dose (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e7649e1f1434f859579699b136ef1e5
https://doi.org/10.21203/rs.3.rs-2559268/v1
https://doi.org/10.21203/rs.3.rs-2559268/v1
Autor:
Masaoki Kohzaki, Akira Ootsuyama, Toshiaki Abe, Manabu Tsukamoto, Toshiyuki Umata, Ryuji Okazaki
Publikováno v:
JBMR Plus. 6
Ionizing radiation (IR) is a well-known carcinogen. High-dose-rate (HDR) IR is known to damage long bones (in terms of mass and structure), but the relationships among dose rates (particularly low-dose-rate [LDR] IR), long-bone condition, cancer inci
Autor:
null Masaoki Kohzaki, null Akira Ootsuyama, null Toshiaki Abe, null Manabu Tsukamoto, null Toshiyuki Umata, null Ryuji Okazaki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d6e2f9c1423c998137d135ff00dea60
https://doi.org/10.1002/jbm4.10688/v2/response1
https://doi.org/10.1002/jbm4.10688/v2/response1
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Tumor suppressor genes are involved in maintaining genome integrity during reproduction (e.g., meiosis). Thus, deleterious alleles in tumor suppressor-deficient mice would exhibit higher mortality during the perinatal period. A recent aging model pro
Autor:
Ryuji Okazaki, Masaoki Kohzaki, Michiaki Kai, Ying Jiang, Tatsuhiko Kubo, Akira Ootsuyama, Toshihiko Sado, Katsunori Suzuki, Seiichiro Tateishi, Koji Mori
Publikováno v:
Journal of radiation research.
We evaluated the correlation between radiation dose and the medical examination data of Tokyo Electric Power Company Holdings, Inc (TEPCO) employees working during the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident in 2011. This study include
Autor:
Akira Ootsuyama
Publikováno v:
Journal of UOEH. 43(1)
In the event of a high-dose radiation exposure accident, adipose-derived stem cell (ADSC) transplantation might be used as an emergency medical treatment to compensate for bone marrow failure. To investigate the possible course of that treatment, we