Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Akira Nifuji"'
Autor:
Satoshi Wada, Hisashi Ideno, Kazuhisa Nakashima, Koichiro Komatsu, Noboru Demura, Hiroshi Tomonari, Hiroshi Kimura, Makoto Tachibana, Akira Nifuji
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract G9a is a histone methyltransferase that catalyzes the methylation of histone 3 lysine 9 (H3K9), which is involved in the regulation of gene expression. We had previously reported that G9a is expressed in developing tendons in vivo and in vit
Externí odkaz:
https://doaj.org/article/60b1bd41739c4e5f90a61448d822048f
Autor:
Zhu Ling, Hailati Aini, Shuhei Kajikawa, Jumpei Shirakawa, Kunikazu Tsuji, Yoshinori Asou, Hideyuki Koga, Ichiro Sekiya, Akira Nifuji, Masaki Noda, Yoichi Ezura
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1395 (2023)
A novel osteolytic disorder due to PFN1 mutation was discovered recently as early-onset Paget’s disease of bone (PDB). Bone loss and pain in adult PDB patients have been treated using bisphosphonates. However, therapeutic strategies for this specif
Externí odkaz:
https://doaj.org/article/63d96df7c0934834be996e83a07c3837
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Tooth ankylosis is a pathological condition of periodontal ligament (PDL) restoration after tooth replantation. Platelet-derived growth factor-BB (PDGF-BB) has been proposed as a promising factor for preventing tooth ankylosis. Using rat too
Externí odkaz:
https://doaj.org/article/d9647e0e96db4f90b040065592f2d538
Publikováno v:
Journal of Physical Fitness and Sports Medicine, Vol 4, Iss 5, Pp 357-362 (2015)
The expression of cell lineage-specific genes during cell differentiation and development is regulated by lineage-specific transcription factors. Recent studies have revealed that epigenetic mechanisms, including post-translational modifications in h
Externí odkaz:
https://doaj.org/article/5ac26f1a99eb48338830e3adf2faa71a
Autor:
Akira Nifuji
Publikováno v:
Journal of Physical Fitness and Sports Medicine, Vol 2, Iss 1, Pp 1-8 (2013)
Vertebrate skeleton consists of numerous pieces of bone and cartilage, each placed at the appropriate anatomical site by an elaborate regulatory process in developmental patterning. In this process, mesenchymal cells initially form aggregates at the
Externí odkaz:
https://doaj.org/article/740f8d4508514ada83c5e67bafa29064
Publikováno v:
genesis. 60
Transplantation and replantation of teeth are effective therapeutic approaches for tooth repositioning and avulsion, respectively. Transplantation involves transplanting an extracted tooth from the original site into another site, regenerating tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224681fbe6cb93f60063914b7c6894e9
https://doi.org/10.1002/dvg.23496
https://doi.org/10.1002/dvg.23496
Publikováno v:
Journal of Bone and Mineral Metabolism.
Profilin-1 (Pfn1), an evolutionarily conserved actin-binding protein, is an important regulator of the cytoskeleton. We previously reported the osteoclast-specific Pfn1-conditional knockout (cKO) mice had postnatal osteolytic phenotype with craniofac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05e75ba1f4715ef70b994c34c848616
https://doi.org/10.1007/s00774-022-01320-y
https://doi.org/10.1007/s00774-022-01320-y
Publikováno v:
Scientific reports. 12(1)
Tooth ankylosis is a pathological condition of periodontal ligament (PDL) restoration after tooth replantation. Platelet-derived growth factor-BB (PDGF-BB) has been proposed as a promising factor for preventing tooth ankylosis. Using rat tooth replan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a1b2e891c3a656ba6a2f1543a44a78
https://pubmed.ncbi.nlm.nih.gov/35217688
https://pubmed.ncbi.nlm.nih.gov/35217688
Autor:
Shoichiro Kokabu, Akira Nifuji, Megumi Yumoto, Tadayoshi Hayata, Eiji Ikami, Naoki Hayashi, Tsuyoshi Sato, Tetsuya Yoda, Y. Sakamoto, Michihiko Usui, Masaki Noda
Publikováno v:
Oral Diseases. 25:274-281
OBJECTIVE Masticatory muscle tendon-aponeurosis hyperplasia, which is associated with limited mouth opening, progresses very slowly from adolescence. The prevalence rates of this disease are higher among women than among men, suggesting oestrogen inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6338e1550f8489f519034954b5d5b9c1
https://doi.org/10.1111/odi.12876
https://doi.org/10.1111/odi.12876
Autor:
Ernst Pöschl, Yoshiki Nakamura, Akemi Shimada, Hiroaki Mizukami, Koichiro Komatsu, Bent Brachvogel, Norio Amizuka, Hisashi Ideno, Akira Nifuji, Kazuhisa Nakashima, Yoshinori Arai, Teruhito Yamashita, Yoichi Ezura, Satoshi Wada
Publikováno v:
Journal of Bone and Mineral Research. 33:1532-1543
Little is known about the molecular mechanisms of enthesis formation in mature animals. Here, we report that annexin A5 (Anxa5) plays a critical role in the regulation of bone ridge outgrowth at the entheses. We found that Anxa5 is highly expressed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::709bcfd1c58da61f37c484a40d6a7d14
https://doi.org/10.1002/jbmr.3453
https://doi.org/10.1002/jbmr.3453