Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Akira Motegi"'
Autor:
Hiroyuki Niida, Ryoichi Matsunuma, Ryo Horiguchi, Chiharu Uchida, Yuka Nakazawa, Akira Motegi, Koji Nishimoto, Satoshi Sakai, Tatsuya Ohhata, Kyoko Kitagawa, Shinichi Moriwaki, Hideo Nishitani, Ayako Ui, Tomoo Ogi, Masatoshi Kitagawa
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Repair of cyclobutane pyrimidine dimers requires access to DNA by the nucleotide excision repair machinery. Here the authors show that HBO1 facilitates accumulation of SNF2H and ACF1 to make chromatin more accessible after ultraviolet damage.
Externí odkaz:
https://doaj.org/article/7b24a512b5c14b5d8915f3a1439eca2b
Autor:
Hiroyuki Niida, Ryoichi Matsunuma, Ryo Horiguchi, Chiharu Uchida, Yuka Nakazawa, Akira Motegi, Koji Nishimoto, Satoshi Sakai, Tatsuya Ohhata, Kyoko Kitagawa, Shinichi Moriwaki, Hideo Nishitani, Ayako Ui, Tomoo Ogi, Masatoshi Kitagawa
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-3 (2018)
Nature Communications 8: Article number: 16102 (2017); Published online 18 July 2017; Updated 20 April 2018 The original version of this Article contained an error in Fig. 1b, in which the cells were incorrectly labelled as ‘HeLa’, rather than th
Externí odkaz:
https://doaj.org/article/b76aa05dd11344338f7436e36f9c1b98
Autor:
Kouji Hirota, Eiichiro Sonoda, Takuo Kawamoto, Akira Motegi, Chikahide Masutani, Fumio Hanaoka, Dávid Szüts, Shigenori Iwai, Julian E Sale, Alan Lehmann, Shunichi Takeda
Publikováno v:
PLoS Genetics, Vol 6, Iss 10 (2010)
Replicative DNA polymerases are frequently stalled by DNA lesions. The resulting replication blockage is released by homologous recombination (HR) and translesion DNA synthesis (TLS). TLS employs specialized TLS polymerases to bypass DNA lesions. We
Externí odkaz:
https://doaj.org/article/8da1f6191d1b461e8ef6c6a2e071181b
Autor:
Masatoshi Kitagawa, Takafumi Suda, Akira Motegi, Kyoko Kitagawa, Tatsuya Ohhata, Chiharu Uchida, Hiroyuki Niida, Koji Nishimoto
Supplementary Figure S1. Depletion of HDAC3 increases UV sensitivity and delays CPD removal. Supplementary Figure S2. HDAC3 does not interact with NER factors in the presence or absence UV irradiation. Supplementary Figure S3. HDAC3 facilitates XPC a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef00ff6612e6f2480f46705cbfcb2d01
https://doi.org/10.1158/1541-7786.22527261.v1
https://doi.org/10.1158/1541-7786.22527261.v1
Autor:
Masatoshi Kitagawa, Takafumi Suda, Akira Motegi, Kyoko Kitagawa, Tatsuya Ohhata, Chiharu Uchida, Hiroyuki Niida, Koji Nishimoto
Recent studies have demonstrated that lysine acetylation of histones is crucial for nucleotide excision repair (NER) by relaxing the chromatin structure, which facilitates the recruitment of repair factors. However, few studies have focused on the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40789c2e85d2884bcd7ce78864fc5b6e
https://doi.org/10.1158/1541-7786.c.6545373.v1
https://doi.org/10.1158/1541-7786.c.6545373.v1
Autor:
Takafumi Koyauchi, Hiroyuki Niida, Akira Motegi, Satoshi Sakai, Chiharu Uchida, Tatsuya Ohhata, Kenta Iijima, Akihiko Yokoyama, Takafumi Suda, Masatoshi Kitagawa
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1869:119332
Ultraviolet (UV) light irradiation generates pyrimidine dimers on DNA, such as cyclobutane pyrimidine dimers (CPDs) and (6-4) photoproducts. Such dimers distort the high-order DNA structure and prevent transcription and replication. The nucleotide ex
Autor:
Koji Nishimoto, Takafumi Suda, Tatsuya Ohhata, Akira Motegi, Chiharu Uchida, Masatoshi Kitagawa, Hiroyuki Niida, Kyoko Kitagawa
Publikováno v:
Molecular cancer research : MCR. 18(9)
Recent studies have demonstrated that lysine acetylation of histones is crucial for nucleotide excision repair (NER) by relaxing the chromatin structure, which facilitates the recruitment of repair factors. However, few studies have focused on the co
Publikováno v:
Seminars in cancer biology. 58
Cancer cells show various types of mutations and aberrant expression in genes involved in DNA repair responses. These alterations induce genome instability and promote carcinogenesis steps and cancer progression processes. These defects in DNA repair
Publikováno v:
Oncotarget
// Junhui Wang 1, 2, * , Qianshan Ding 3, * , Hiroaki Fujimori 1, 5 , Akira Motegi 4 , Yoshio Miki 2 , Mitsuko Masutani 1, 5 1 Division of Chemotherapy and Clinical Cancer Research, National Cancer Center Research Institute, Tokyo 104-0045, Japan 2 D
Autor:
Norio Nakatsuji, Minoru Takata, Masamichi Ishiai, Akira Motegi, Ayako L. Mochizuki, Emiko Moribe, Hitomi Watanabe, Gen Kondoh, Eri Hayashi, Shinichiro Chuma, Mihoko Hosokawa, Ami Katanaya
DNA replication is frequently perturbed by intrinsic, as well as extrinsic, genotoxic stress. At damaged forks, DNA replication and repair activities require proper coordination to maintain genome integrity. We show here that PARI antirecombinase pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8724f136610b78e7f03a8687da97f1
https://europepmc.org/articles/PMC5686578/
https://europepmc.org/articles/PMC5686578/