Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Akira Imagawa"'
Autor:
Atsushi Hiramatsu, Hiroto Ota, Makoto Katoh, Shingo Nakatani, Taihei Nishiyama, Masahiro Okada, Hiroshi Saga, Juta Kobayashi, Toshihide Watanabe, Tatsuo Maeda, Naoya Matsumura, Shingo Yamamoto, Akira Imagawa, Katsuya Hisaichi, Hideki Moriguchi, Yuka Komichi, Yuzo Iwaki, Tetsuya Sugiyama, Hirooka Yasuo, Yasuyuki Okabe, Akira Ohhata
Publikováno v:
ACS Med Chem Lett
[Image: see text] Lysophosphatidic acid (LPA) is a bioactive lipid mediator that elicits a number of biological functions, including smooth muscle contraction, cell motility, proliferation, and morphological change. LPA is endogenously produced by au
Autor:
Masanori Iwaki, Hidenori Miyata, Atsushi Naganawa, Akira Imagawa, Takuya Nishio, Jun Katagi, Yasuyuki Okabe, Takeshi Matsushita, Tatsuya Komagata, Akiharu Ishida, Toru Maruyama, Tetsuya Sekiguchi
Publikováno v:
Bioorganic & Medicinal Chemistry. 49:116424
Somatostatin receptors are members of G-protein coupled receptor superfamily. Receptors can be classified into five subtypes, SSTR1 to 5. The highly potent and orally active SSTR2 agonist 7, which had been identified by our group, was found out to ha
Autor:
Masashi Gohda, Kenji Tanaka, Hiromu Habashita, Sho Koyama, Tetsuya Hagio, Kazuhito Kawabata, Akira Imagawa, Hidekazu Matsuya, Masaru Sakai, Yasushi Hirota, Yasuo Yonetomi, Taihei Nishiyama, Ai Hashimoto, Takehiro Ono, Shinya Sakimoto
Publikováno v:
Stroke. 48
Background and Purpose: High levels of blood coagulation factor XI (FXI) are an established risk factor for acute ischemic stroke and thrombosis. Patients with severe FXI deficiency have a low risk of ischemic stroke. In addition, FXI-deficient or an
Autor:
Akira, Imagawa, Keitaro, Tanaka
Publikováno v:
同志社政策科学研究 = Doshisha University policy & management review. 14(1):17-31
本稿では、カンザス大学のジョージ・フレデリクソン教授らの研究による「シティ・マネージャーモデル」と「市長・議会モデル」が深く融合した「完全融合モデル」と、その典型例と
Autor:
Akira, Imagawa, Satoshi, Miura
Publikováno v:
同志社政策研究 = Doshisha University Policy Studies. 4:158-176
近年、「地域力再生」が大きな注目を集め、これを意図した取り組みが各地で展開されている。そこで、本稿は地域力を「コミュニティによる地域課題の発見力・解決力」ととらえ、従
Autor:
Akira, Imagawa, Yoshimitsu, Araki
Publikováno v:
社会科学 = The Social Science(The Social Sciences). 81:25-33
調査
Autor:
Akira, Imagawa, Yoshimitsu, Araki
Publikováno v:
社会科学 = The Social Science(The Social Sciences). 79:159-171
市町村行政における地域保健部局が担うべき役割を考察し、健康づくりに資する評価指標研究のポイントを検討するために、民生委員・児童委員等の住民に対する意識調査を行い、以下
Autor:
Akira, Imagawa
Publikováno v:
同志社政策研究 = Doshisha University Policy Studies. 1:86-93
住民参加、行政評価・政策評価、行政苦情救済の3つの領域から新たな動きの整理を行い、従来の行政統制論の理解を修正する必要性を指摘した。
研究ノート
研究ノート
Autor:
Yoshisuke Nakayama, Yasuo Yonetomi, Akiharu Ishida, Satoshi Itadani, Akira Imagawa, Hiroaki Nomura, Junya Ueda, Katsuya Hisaichi, Kazuyuki Ohmoto, Masaki Ima, Nobukazu Ohta, Takeshi Nabe, Hiromu Egashira, Atsushi Kinoshita, Tetsuya Kitamine, Michiaki Kadode, Hideki Moriguchi, Manabu Fujita, Yoshiyuki Aratani, Tomohiko Sekioka, Kentaro Yashiro, Yohei Tajima, Yoshiyuki Yamaura, Tetsuya Sekiguchi, Takafumi Nakao, Atsuto Inoue, Naoya Matsumura, Shinya Takahashi, Jun Takeuchi
Publikováno v:
Journal of medicinal chemistry. 58(15)
An orally active dual CysLT1 and CysLT2 antagonist possessing a distinctive structure which consists of triple bond and dicarboxylic acid moieties is described. Gemilukast (ONO-6950) was generated via isomerization of the core indole and the incorpor
Autor:
Akira Imagawa, Hiroshi Mori, Yasuo Ochi, Makoto Tanaka, Kazuyuki Ohmoto, Hiroyuki Yamada, Naoki Kawada, Kazuhito Kawabata
Publikováno v:
Journal of bone and mineral metabolism. 34(1)
This study examined the effects of a novel cathepsin K inhibitor, ONO-KK1-300-01 (KK1-300), used concurrently with parathyroid hormone (PTH) in ovariectomized (OVX) rats. KK1-300 (3 mg/kg, twice daily), alendronate (1 mg/kg, once daily) or vehicle we