Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Akira Harazono"'
Autor:
Yuhsuke Ohmi, Wataru Ise, Akira Harazono, Daisuke Takakura, Hidehiro Fukuyama, Yoshihiro Baba, Masashi Narazaki, Hirofumi Shoda, Nobunori Takahashi, Yuki Ohkawa, Shuting Ji, Fumihiro Sugiyama, Keishi Fujio, Atsushi Kumanogoh, Kazuhiko Yamamoto, Nana Kawasaki, Tomohiro Kurosaki, Yoshimasa Takahashi, Koichi Furukawa
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Post-translational modifications, such as glycosylation and sialylation, are thought to confer disease modifying effects on autoimmune-associated antibodies, including anti-citrullinated protein antibodies in rheumatoid arthritis. Here the authors sh
Externí odkaz:
https://doaj.org/article/626de5323ebb454892d4e77327d0fdec
Autor:
Miwako Asanuma, Nana Kawasaki, Yuki Kobayashi, Kazumi Saikusa, Ryuichi Sawa, Kazutaka Shimbo, Kana Tanabe, Kohei Nozawa, Akira Harazono, Akira Motoyama, Hiroaki Akutsu, Seiko Oka, Shigeki Jin, Yusuke Takata, Ken-ichi Bajo, Tomohiro Hirose, Ayako Mori, Daisuke Saigusa, Emiko Sato, Tomoyoshi Soga, Akiyoshi Hirayama, Masamitsu Maekawa, Nariyasu Mano, Ken-ichi Yoshino, Issey Osaka, Sadamu Kurono, Keiko Kuwata, Tatsuko Sakai, Mitsutoshi Setou, Yutaka Takahashi, Yasuhide Naito, Tomohiro Matsumoto
Publikováno v:
Journal of the Mass Spectrometry Society of Japan. 70:85-89
Autor:
Hiroko Shibata, Masahiro Terabe, Yuriko Shibano, Satoshi Saitoh, Tomohiro Takasugi, Yu Hayashi, Shinji Okabe, Yuka Yamaguchi, Hidehito Yasukawa, Hiroyuki Suetomo, Kazuhiro Miyanabe, Naomi Ohbayashi, Michiko Akimaru, Shuntaro Saito, Daisuke Ito, Atsushi Nakano, Shota Kojima, Yuya Miyahara, Kenji Sasaki, Takahiro Maruno, Masanori Noda, Masato Kiyoshi, Akira Harazono, Tetsuo Torisu, Susumu Uchiyama, Akiko Ishii-Watabe
Publikováno v:
Journal of pharmaceutical sciences. 111(10)
In this study, we conducted a collaborative study on the classification between silicone oil droplets and protein particles detected using the flow imaging (FI) method toward proposing a standardized classifier/model. We compared four approaches, inc
Autor:
Miyako Nakano, Alena Wiegandt, Yunli Hu, Viv Lindo, Paulina A. Urbanowicz, Zsuzsanna Lakos, Cassie Caron, Song Klapoetke, Niels Christian Reichardt, Niclas Chiang Tan, Sandra Maier, Rene Hennig, Marton Szigeti, Ju Yeon Lee, Ying Qing Yu, Gregory O. Staples, Sachin Patil, Jolanta Jaworek, Waltraud Evers, Benjamin G. Kremkow, Youngsuk Seo, Kathirvel Alagesan, Yuetian Chen, Gordan Lauc, David L. Duewer, Yang Yang, Daniele Menard, Hyun Joo An, Tim Kelly, Stephen E. Stein, Joseph W. Leone, Anja Wiechmann, Ravi Amunugama, Peng George Wang, Clemens Grunwald-Grube, Maria Lorna A. De Leoz, Göran Larson, Rob Haselberg, Samanta Cajic, Stephanie A. Archer-Hartmann, Maja Pučić-Baković, Edward D. Bodnar, Pauline M. Rudd, Anja Resemann, Daniel Kolarich, Akira Harazono, Jeffrey S. Rohrer, Juan Echevarria Ruiz, Stuart Pengelley, Jong Shin Yoo, Arun V. Everest-Dass, Nicolle H. Packer, Steven W. Mast, William R. Alley, Erika Lattová, Anne Zeck, Corné J.M. Stroop, Radoslaw P. Kozak, Chun Shao, Alain Beck, Joseph Zaia, Erdmann Rapp, Lily Liu, Jennie Truong, Yaojun Wang, Christopher W. Cairo, Roisin O'Flaherty, Radka Saldova, Kudrat Goswami, Emy Komatsu, Jessica Örnros, Taiki Sugiyama, Prachi Bhoskar, Pralima Pradhan, Carlito B. Lebrilla, András Guttman, Christine Merle, Brian Kasper, Oscar G. Potter, Soo Kyung Suh, Li Phing Liew, Ranjan Chakrabarti, Terry D. Cyr, Sohei Funaoka, Masaaki Toyoda, Pui King Amy Leung, Toyin Kasali, Jerko Štambuk, Yanming An, Wolfgang Jabs, Bernd Meyer, Chunxia Zou, John F. Cipollo, Sa Rang Kim, Aaron Shafer, Randy M. Whittal, Jichao Kang, Albert J. R. Heck, Yehia Mechref, Hoi Kei Yau, Guinevere S. M. Lageveen-Kammeijer, Shiwei Sun, Kenichiro Furuki, Richard B. Jones, Béla Reiz, Niclas G. Karlsson, Mohammedazam Lahori, Xu Li, Barbara Adamczyk, Rui Cao, Lauren Wu, Koichi Kato, Detlev Suckau, Paweł Link-Lenczowski, Kelvin H. Lee, Xiaomin Song, Noortje de Haan, Ruth Frenkel, Adam Fung, Friedrich Altmann, Manfred Wuhrer, David Falck, Andreas Bock, Paula Magnelli, Brian Gau, Sachiko Kondo, Robert J. Emery, Chunsheng Jin, Louise Royle, David C. Muddiman, Hélène Perreault, John W. Froehlich, Disha Dadke, Peiqing Zhang, Lara K. Mahal, Takashi Nishikaze, Andrew Saati, Chuncui Huang, Hui Zhang, Carina Sihlbom, Parastoo Azadi, Jonas Nilsson, Yaming Liu, Yannis-Nicolas François, Nassur Said, Jin Young Kim, C. T. Yuen, Shuang Yang, Emmanuelle Leize-Wagner, David Harvey, Xiaofeng Shi, Yan Li, Hirokazu Yagi, Zoran Sosic, Elizabeth M. Hecht, Hua Yuan, Marybeth Creskey, Hyun Kyoung Lee, Sadanori Sekiya, Peter de Vreugd, Len Bell, Sam Tep
Publikováno v:
De Leoz, M L A, Duewer, D L, Fung, A, Liu, L, Yau, H K, Potter, O, Staples, G O, Furuki, K, Frenkel, R, Hu, Y, Sosic, Z, Zhang, P, Altmann, F, Gru Nwald-Grube, C, Shao, C, Zaia, J, Evers, W, Pengelley, S, Suckau, D, Wiechmann, A, Resemann, A, Jabs, W, Beck, A, Froehlich, J W, Huang, C, Li, Y, Liu, Y, Sun, S, Wang, Y, Seo, Y, An, H J, Reichardt, N C, Ruiz, J E, Archer-Hartmann, S, Azadi, P, Bell, L, Lakos, Z, An, Y, Cipollo, J F, Pucic-Bakovic, M, Štambuk, J, Lauc, G, Li, X, Wang, P G, Bock, A, Hennig, R, Rapp, E, Creskey, M, Cyr, T D, Nakano, M, Sugiyama, T, Leung, P K A, Link-Lenczowski, P, Jaworek, J, Yang, S, Zhang, H, Kelly, T, Klapoetke, S, Cao, R, Kim, J Y, Lee, H K, Lee, J Y, Yoo, J S, Kim, S R, Suh, S K, de Haan, N, Falck, D, Lageveen-Kammeijer, G S M, Wuhrer, M, Emery, R J, Kozak, R P, Liew, L P, Royle, L, Urbanowicz, P A, Packer, N H, Song, X, Everest-Dass, A, Lattová, E, Cajic, S, Alagesan, K, Kolarich, D, Kasali, T, Lindo, V, Chen, Y, Goswami, K, Gau, B, Amunugama, R, Jones, R, Stroop, C J M, Kato, K, Yagi, H, Kondo, S, Yuen, C T, Harazono, A, Shi, X, Magnelli, P E, Kasper, B T, Mahal, L, Harvey, D J, O'Flaherty, R, Rudd, P M, Saldova, R, Hecht, E S, Muddiman, D C, Kang, J, Bhoskar, P, Menard, D, Saati, A, Merle, C, Mast, S, Tep, S, Truong, J, Nishikaze, T, Sekiya, S, Shafer, A, Funaoka, S, Toyoda, M, de Vreugd, P, Caron, C, Pradhan, P, Tan, N C, Mechref, Y, Patil, S, Rohrer, J S, Chakrabarti, R, Dadke, D, Lahori, M, Zou, C, Cairo, C, Reiz, B, Whittal, R M, Lebrilla, C B, Wu, L, Guttman, A, Szigeti, M, Kremkow, B G, Lee, K H, Sihlbom, C, Adamczyk, B, Jin, C, Karlsson, N G, Örnros, J, Larson, G, Nilsson, J, Meyer, B, Wiegandt, A, Komatsu, E, Perreault, H, Bodnar, E D, Said, N, Francois, Y N, Leize-Wagner, E, Maier, S, Zeck, A, Heck, A J R, Yang, Y, Haselberg, R, Yu, Y Q, Alley, W, Leone, J W, Yuan, H & Stein, S E 2020, ' NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies : Comparison of Results from Diverse Analytical Methods ', MCP : Molecular & cellular proteomics, vol. 19, no. 1, pp. 11-30 . https://doi.org/10.1074/mcp.RA119.001677
Molecular and Cellular Proteomics, 19(1), 11-30. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
MCP : Molecular & cellular proteomics, 19(1), 11-30. American Society for Biochemistry and Molecular Biology Inc.
Molecular & Cellular Proteomics
Molecular & Cellular Proteomics, 19(1), 11-30. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Molecular and Cellular Proteomics
Molecular and Cellular Proteomics, American Society for Biochemistry and Molecular Biology, 2019, mcp.RA119.001677. ⟨10.1074/mcp.RA119.001677⟩
Molecular and Cellular Proteomics, 19(1), 11. American Society for Biochemistry and Molecular Biology Inc.
Molecular & Cellular Proteomics : MCP
Molecular and Cellular Proteomics, 19(1), 11-30. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
MCP : Molecular & cellular proteomics, 19(1), 11-30. American Society for Biochemistry and Molecular Biology Inc.
Molecular & Cellular Proteomics
Molecular & Cellular Proteomics, 19(1), 11-30. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Molecular and Cellular Proteomics
Molecular and Cellular Proteomics, American Society for Biochemistry and Molecular Biology, 2019, mcp.RA119.001677. ⟨10.1074/mcp.RA119.001677⟩
Molecular and Cellular Proteomics, 19(1), 11. American Society for Biochemistry and Molecular Biology Inc.
Molecular & Cellular Proteomics : MCP
A broad-based interlaboratory study of glycosylation profiles of a reference and modified IgG antibody involving 103 reports from 76 laboratories.
Graphical Abstract Highlights A broad-based interlaboratory study of the glycosylation of a refere
Graphical Abstract Highlights A broad-based interlaboratory study of the glycosylation of a refere
Autor:
Yasukawa Hidehito, Hiroko Shibata, Masato Kiyoshi, Hiroaki Murase, Takuma Ojima, Taiichiro Ogawa, Takashi Kumagai, Susumu Uchiyama, Yukari Itakura, Shuntaro Saito, Hiroyuki Suetomo, Takahiro Maruno, Naoki Mori, Hirotaka Nishimura, Satoshi Saitoh, Kazuhiro Takegami, Yuuka Asano, Akiko Ishii-Watabe, Akira Harazono, Momoko Takeuchi, Mai Hirokawa, Aya Kikitsu, Takafumi Iwura, Tetsuo Torisu, Okabe Shinji, Michiko Akimaru, Atsushi Oda, Keisuke Ikemoto
Publikováno v:
Journal of Pharmaceutical Sciences. 108:832-841
The evaluation of subvisible particles, including protein aggregates, in therapeutic protein products has been of great interest for both pharmaceutical manufacturers and regulatory agencies. To date, the flow imaging (FI) method has emerged as a pow
Autor:
Akira Harazono, Masato Kiyoshi, Jun Fukuda, Tetsuo Torisu, Susumu Uchiyama, Hiroko Shibata, Takashi Muto, Akiko Ishii-Watabe, Hirotaka Nishimura, Satoshi Saitoh
Publikováno v:
Biologicals. 57:46-49
Insoluble particulate matter test for injections in pharmacopoeia is mandatory for parenteral drug products. In this test using light obscuration, four measurements of at least 5-mL are required. Since therapeutic protein injections of low dosage vol
Autor:
Masashi Hyuga, Satoshi Saitoh, Tetsuo Torisu, Michihiko Aoyama, Hiroko Shibata, Yukihiro Goda, Takashi Muto, Hiroyuki Suetomo, Masato Kiyoshi, Yukako Tanaka, Takafumi Iwura, Akira Harazono, Susumu Uchiyama, Srivalli Telikepalli, Yosuke Ikeda, Yu Hayashi, Akiko Ishii-Watabe, Satomi Ueda
Publikováno v:
Journal of pharmaceutical sciences. 109(5)
As reported in the previous commentary (Ishii-Watabe et al., J Pharm Sci 2017), the Japanese biopharmaceutical research group is promoting collaborative multilaboratory studies to evaluate and standardize new methodologies for biopharmaceutical chara
Autor:
Hiroko Shibata, Toru Tanaka, Hiroko Tamura, Akiko Ishii-Watabe, Terao Yosuke, Jose M. M. Caaveiro, Seigo Oe, Teruhiko Ide, Akira Harazono, Satoru Nagatoishi, Noritaka Hashii, Daisuke Kuroda, Kouhei Tsumoto, Koldo Morante, Minoru Tada, Masato Kiyoshi
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
The N-glycan moiety of IgG-Fc has a significant impact on multifaceted properties of antibodies such as in their effector function, structure, and stability. Numerous studies have been devoted to understanding its biological effect since the exact co
Autor:
Akio Matsuda, Masato Kiyoshi, Minoru Tada, Noritaka Hashii, Akiko Ishii-Watabe, Kenji Osumi, Akira Harazono, Michihiko Aoyama, Wataru Tsukimura
Publikováno v:
mAbs
Typical crystallizable fragment (Fc) glycans attached to the CH2 domain in therapeutic monoclonal antibodies (mAbs) are core-fucosylated and asialo-biantennary complex-type glycans, e.g., G2F (full galactosylation), G1aF (terminal galactosylation on
Autor:
Akira Harazono
Publikováno v:
Journal of the Mass Spectrometry Society of Japan. 64:93-96