Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Akira Haji"'
Autor:
Kengo Suzuki, Yoshiaki Ohi, Toyohiro Sato, Yo Tsuda, Yuta Madokoro, Masayuki Mizuno, Kenichi Adachi, Yuto Uchida, Akira Haji, Kosei Ojika, Noriyuki Matsukawa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Cholinergic activation can enhance glutamatergic activity in the hippocampus under pathologic conditions, such as Alzheimer’s disease. The aim of the present study was to elucidate the relationship between glutamatergic neural functional d
Externí odkaz:
https://doaj.org/article/f0d111b92de54a0c9d61c73a4666cc42
Publikováno v:
Journal of Pharmacological Sciences, Vol 140, Iss 3, Pp 305-309 (2019)
The present study evaluated the ability of progesterone to alleviate the synaptic transmission disturbed by hypoxia in the nucleus tractus solitarius (NTS). Hypoxia with N2 inhibited spontaneous and tractus solitarius-evoked excitatory postsynaptic c
Externí odkaz:
https://doaj.org/article/add66ec325e4401ea14987f69b5481a7
Publikováno v:
Journal of Pharmacological Sciences, Vol 130, Iss 3, Pp 181-184 (2016)
This study was performed to clarify mechanisms underlying pentazocine-induced ventilatory depression and antinociception. Spontaneous ventilation and hind leg withdrawal response against nociceptive thermal stimulation were simultaneously recorded in
Externí odkaz:
https://doaj.org/article/f851f17d0c2f43d89fc215f3a49a5869
Autor:
Toyohiro Sato, Yoshiaki Ohi, Daisuke Kato, Masayuki Mizuno, Hiroshi Takase, Tetsuko Kanamori, Cesar V. Borlongan, Akira Haji, Noriyuki Matsukawa
Publikováno v:
Cell Transplantation, Vol 26 (2017)
Despite having pathological changes in the brain associated with Alzheimer's disease (AD), some patients have preserved cognitive function. A recent epidemiological study has shown that diet, exercise, cognitive training, and vascular risk monitoring
Externí odkaz:
https://doaj.org/article/5961be96d30b4084b7ced9d315c280f0
Publikováno v:
Journal of Pharmacological Sciences, Vol 116, Iss 1, Pp 54-62 (2011)
Abstract.: Dextromethorphan (DEX) is a widely used non-opioid antitussive. However, the precise site of action and its mechanism were not fully understood. We examined the effects of DEX on AMPA receptor–mediated glutamatergic transmission in the n
Externí odkaz:
https://doaj.org/article/10e13fe4d8fe4b48b7f6ed4e475dfc77
Publikováno v:
Journal of Pharmacological Sciences, Vol 112, Iss 4, Pp 477-481 (2010)
The role of platelet-derived growth factor (PDGF)-BB / PDGF receptor (PDGFR)-β signal in inhibition of synaptic transmission by hypoxia is unclear. In the nucleus tractus solitarius neurons, hypoxia with N2 or NaCN decreased the amplitude of excitat
Externí odkaz:
https://doaj.org/article/eb19682347e248768bcfe118db6e68ad
Publikováno v:
Journal of Pharmacological Sciences, Vol 110, Iss 3, Pp 270-275 (2009)
Abstract.: The present study investigated whether the platelet-derived growth factor receptor (PDGFR)-β–mediated mechanisms are involved in the hypoxic ventilatory response through modulating the N-methyl-D-aspartate (NMDA) function. The ventilato
Externí odkaz:
https://doaj.org/article/14781007c0264856b563f83f25a2610f
Autor:
Kiyoshi Minamizawa, Hirozo Goto, Yoshiaki Ohi, Yutaka Shimada, Katsutoshi Terasawa, Akira Haji
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 1, Pp 136-142 (2006)
d-Pseudoephedrine (PSE) is one of the main ingredients of Ephedrae herba. Although PSE is widely applied for patients with a common cold and upper respiratory inflammation as a decongestant, the effects of PSE on cough have never been reported. In th
Externí odkaz:
https://doaj.org/article/b5b0affaa1d84403baec9bdf5aab03e8
Publikováno v:
Brain Research. 1715:115-125
Prostaglandin E2 (PGE2) synthesized in the central nervous system influences various physiological functions including nociception. Recently, we have demonstrated that PGE2 facilitates spontaneous synaptic transmission through presynaptic EP1 recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f61bb3111e663782b69183aa3f43ffd7
https://doi.org/10.1016/j.brainres.2019.03.015
https://doi.org/10.1016/j.brainres.2019.03.015
Publikováno v:
European journal of pharmacology. 913
The present study examined contribution of the transient receptor potential vanilloid 1 channel (TRPV1) to the chronic orofacial pain. Bilateral partial nerve ligation (PNL) of the mental nerve, a branch of trigeminal nerve, was performed to induce n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd085b573eab287582d0fdc9066f773
https://pubmed.ncbi.nlm.nih.gov/34758353
https://pubmed.ncbi.nlm.nih.gov/34758353