Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Akira Futatsugi"'
Autor:
Takashi Sugiyama, Naoya Murao, Hisae Kadowaki, Keizo Takao, Tsuyoshi Miyakawa, Yosuke Matsushita, Toyomasa Katagiri, Akira Futatsugi, Yohei Shinmyo, Hiroshi Kawasaki, Juro Sakai, Kazutaka Shiomi, Masamitsu Nakazato, Kohsuke Takeda, Katsuhiko Mikoshiba, Hidde L. Ploegh, Hidenori Ichijo, Hideki Nishitoh
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102758- (2021)
Summary: Derlin family members (Derlins) are primarily known as components of the endoplasmic reticulum-associated degradation pathway that eliminates misfolded proteins. Here we report a function of Derlins in the brain development. Deletion of Derl
Externí odkaz:
https://doaj.org/article/b69667e8cdc0451bb9c8130fc2b00445
Autor:
Kei Nakayama, Rie Ohashi, Yo Shinoda, Maya Yamazaki, Manabu Abe, Akihiro Fujikawa, Shuji Shigenobu, Akira Futatsugi, Masaharu Noda, Katsuhiko Mikoshiba, Teiichi Furuichi, Kenji Sakimura, Nobuyuki Shiina
Publikováno v:
eLife, Vol 6 (2017)
Local regulation of synaptic efficacy is thought to be important for proper networking of neurons and memory formation. Dysregulation of global translation influences long-term memory in mice, but the relevance of the regulation specific for local tr
Externí odkaz:
https://doaj.org/article/4875eefca281406f8276b441b6dc8f78
Autor:
Akira Futatsugi, Katsuhiko Mikoshiba, Haruna Kitano, Mariko Yokoyama, Kazuhiko Yanai, Yo Yamada, Takuro Matsuzawa, Fumito Naganuma, Takeo Yoshikawa, Anikó Kárpáti
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Histamine is an important neurotransmitter that contributes to various processes, including the sleep-wake cycle, learning, memory, and stress responses. Its actions are mediated through histamine H1–H4 receptors. Gene knockout and pharmacological
Autor:
Akira Futatsugi, Hideki Nishitoh, Tsuyoshi Miyakawa, Kazutaka Shiomi, Yohei Shinmyo, Masamitsu Nakazato, Keizo Takao, Juro Sakai, Hidde L. Ploegh, Kohsuke Takeda, Hisae Kadowaki, Hidenori Ichijo, Yosuke Matsushita, Katsuhiko Mikoshiba, Naoya Murao, Hiroshi Kawasaki, Toyomasa Katagiri, Takashi Sugiyama
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102758-(2021)
iScience
iScience
Summary Derlin family members (Derlins) are primarily known as components of the endoplasmic reticulum-associated degradation pathway that eliminates misfolded proteins. Here we report a function of Derlins in the brain development. Deletion of Derli
Autor:
Anikó, Kárpáti, Takeo, Yoshikawa, Fumito, Naganuma, Takuro, Matsuzawa, Haruna, Kitano, Yo, Yamada, Mariko, Yokoyama, Akira, Futatsugi, Katsuhiko, Mikoshiba, Kazuhiko, Yanai
Publikováno v:
Scientific Reports
Histamine is an important neurotransmitter that contributes to various processes, including the sleep-wake cycle, learning, memory, and stress responses. Its actions are mediated through histamine H1–H4 receptors. Gene knockout and pharmacological
Autor:
Akihiro Fujikawa, Kei Nakayama, Teiichi Furuichi, Manabu Abe, Shuji Shigenobu, Nobuyuki Shiina, Masaharu Noda, Akira Futatsugi, Rie Ohashi, Yo Shinoda, Katsuhiko Mikoshiba, Maya Yamazaki, Kenji Sakimura
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Local regulation of synaptic efficacy is thought to be important for proper networking of neurons and memory formation. Dysregulation of global translation influences long-term memory in mice, but the relevance of the regulation specific for local tr
Autor:
Shuji Shigenobu, Akira Futatsugi, Maya Yamazaki, Teiichi Furuichi, Katsuhiko Mikoshiba, Yo Shinoda, Manabu Abe, Rie Ohashi, Kenji Sakimura, Masaharu Noda, Akihiro Fujikawa, Kei Nakayama, Nobuyuki Shiina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d9070ece527bd83592769b7c8647943
https://doi.org/10.7554/elife.29677.029
https://doi.org/10.7554/elife.29677.029
Autor:
Takafumi Hasegawa, Keiichi Tamai, Atsushi Takeda, Nobuyuki Tanaka, Akio Kikuchi, Shun Yoshida, Akira Futatsugi, Naoto Sugeno, Masashi Aoki, Ikuro Sato, Toru Baba, Junpei Kobayashi, Ryuji Oshima, Kennichi Satoh
Publikováno v:
Scientific Reports
Endosomal sorting required for transport (ESCRT) complexes orchestrate endo-lysosomal sorting of ubiquitinated proteins, multivesicular body formation and autophagic degradation. Defects in the ESCRT pathway have been implicated in many neurodegenera
Autor:
Michael J. Iadarola, Ashok B. Kulkarni, Parvathi Rudrabhatla, Harish C. Pant, Akira Futatsugi, Elias Utreras, Jason M. Keller
Publikováno v:
Journal of Biological Chemistry. 284:2275-2284
Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase. We have previously reported that Cdk5 participates in the regulation of nociceptive signaling, and the expression of Cdk5 and its activator, p35, are up-regulated in noci
Autor:
Kiyomitsu Miyachi, Akihiro Mizutani, Akira Futatsugi, Chihiro Hisatsune, Takeshi Nakamura, Katsuhiko Mikoshiba
Publikováno v:
Cornea. 27:S3-S8
Inositol 1,4,5-trisphosphate (IP3) is a second messenger that induces the release of calcium from the endoplasmic reticulum (ER). The IP3 receptor was discovered as a developmentally regulated glycophosphoprotein, P400, that is absent in strains of m