Zobrazeno 1 - 10
of 2 172
pro vyhledávání: '"Akira Shimizu"'
Autor:
Daisuke Katagiri, Shinya Nagasaka, Keiko Takahashi, Suwan Wang, Ambra Pozzi, Roy Zent, Akira Shimizu, Ming-Zhi Zhang, Joachim R. Göthert, Toin H. van Kuppevelt, Raymond C. Harris, Takamune Takahashi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract The pivotal role of endothelial nitric oxide synthase (eNOS) in diabetic nephropathy (DN) has been demonstrated using global eNOS knockout (eNOSGKO) mice. However, the precise role of endothelially expressed eNOS and how its deficiency advan
Externí odkaz:
https://doaj.org/article/125f4f510b7148eca883ffbfed925244
Autor:
Hayato Takeda, Jun Akatsuka, Tomonari Kiriyama, Yuka Toyama, Yasushi Numata, Hiromu Morikawa, Kotaro Tsutsumi, Mami Takadate, Hiroya Hasegawa, Hikaru Mikami, Kotaro Obayashi, Yuki Endo, Takayuki Takahashi, Manabu Fukumoto, Ryuji Ohashi, Akira Shimizu, Go Kimura, Yukihiro Kondo, Yoichiro Yamamoto
Publikováno v:
Current Oncology, Vol 31, Iss 11, Pp 7180-7189 (2024)
Prostate cancer (PCa) is a clinically heterogeneous disease. Predicting clinically significant PCa with low–intermediate prostate-specific antigen (PSA), which often includes aggressive cancers, is imperative. This study evaluated the predictive ac
Externí odkaz:
https://doaj.org/article/24f19a96097940b18699af9ddd9e7f52
Autor:
Kiyotaka Hosoda, Akira Shimizu, Koji Kubota, Tsuyoshi Notake, Noriyuki Kitagawa, Takahiro Yoshizawa, Hiroki Sakai, Hikaru Hayashi, Koya Yasukawa, Yuji Soejima
Publikováno v:
Annals of Gastroenterological Surgery, Vol 8, Iss 6, Pp 1096-1106 (2024)
Abstract Aim Methods of predicting severe postoperative complications after anatomical resection for hepatocellular carcinoma are yet to be established. We aimed to clarify the relationship between inflammation‐based prognostic scores and liver fib
Externí odkaz:
https://doaj.org/article/01ca81ab85ea45e4b8ccab7022beb18d
Publikováno v:
Annals of Gastroenterological Surgery, Vol 8, Iss 6, Pp 1137-1143 (2024)
Abstract Median arcuate ligament syndrome (MALS) is a rare condition characterized by nonspecific symptoms, such as abdominal pain, nausea, and vomiting. Furthermore, the development and rupture of pancreaticoduodenal artery aneurysms pose a potentia
Externí odkaz:
https://doaj.org/article/5d0fe2a3068e4d7892e08bdff6001a8d
Autor:
Yugo Okabe, Etsuko Toda, Hirokazu Urushiyama, Yuya Terashima, Shinobu Kunugi, Yusuke Kajimoto, Mika Terasaki, Kouji Matsushima, Akira Saito, Yasuhiro Yamauchi, Takahide Nagase, Akira Shimizu, Yasuhiro Terasaki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The accumulation of monocyte-derived macrophages in the lung tissue during inflammation is important for the pathogenesis of fibrotic lung disease. Deficiencies in chemokine receptors CCR2 and CCR5 and their ligands, which mediate monocyte/m
Externí odkaz:
https://doaj.org/article/cfa154cc344f4a1a9d413d09cb985598
Autor:
Kazuhiro Takeuchi, Sayumi Kawamura, Yukihiro Wada, Emi Sakamoto, Hideaki Kuno, Shun Sakurabayashi, Tomomi Motohashi, Hiroyuki Okawa, Naohiro Kawamura, Shokichi Naito, Togo Aoyama, Akira Shimizu, Yasuo Takeuchi
Publikováno v:
Case Reports in Nephrology and Dialysis, Vol 14, Iss 1, Pp 128-137 (2024)
Introduction: Drug-induced tubulointerstitial injury is a common cause of renal impairment. Since the mechanisms of drug-induced tubular injury are diverse, various treatment approaches are needed according to the pathogenesis. Renal biopsy is indisp
Externí odkaz:
https://doaj.org/article/18d92669ef3f461fb35f9b60cb54e16f
Publikováno v:
Journal of Cutaneous Immunology and Allergy, Vol 7 (2024)
Lichen nitidus is a chronic skin disease characterized by scattered shiny papules and is common among relatively young individuals. We report a persistent rash covering the body of a 6-year-old boy, unresponsive to prior treatments like moisturizers
Externí odkaz:
https://doaj.org/article/23b7c3559dfc42679523972e64f6bd77
Autor:
Hitoshi Goto, Takeshi Arima, Akira Takahashi, Yutaro Tobita, Yuji Nakano, Etsuko Toda, Akira Shimizu, Fumiki Okamoto
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Alkaline burns to the cornea lead to loss of corneal transparency, which is essential for normal vision. We used a rat corneal alkaline burn model to investigate the effect of ophthalmic trimebutine solution on healing wounds caused by alkal
Externí odkaz:
https://doaj.org/article/39ac1a18cf6648be8780d85c30e3435b
Autor:
Weili Chen, Etsuko Toda, Kazuhiro Takeuchi, Yurika Sawa, Kyoko Wakamatsu, Naomi Kuwahara, Arimi Ishikawa, Yuri Igarashi, Mika Terasaki, Shinobu Kunugi, Yasuhiro Terasaki, Kazuhiko Yamada, Yuya Terashima, Akira Shimizu
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Antibody responses, involving B cells, CD4 + T cells, and macrophages, are implicated in autoimmune diseases and organ transplant rejection. We have previously shown that inhibiting FROUNT with disulfiram (DSF) suppresses macrophage activati
Externí odkaz:
https://doaj.org/article/9f13f9b31b5c48b5a78ad3403f60e7fc
Autor:
Daniel Eisenson, Yu Hisadome, Michelle Santillan, Hayato Iwase, WeiLi Chen, Akira Shimizu, Alex Schulick, Du Gu, Armaan Akbar, Alice Zhou, Kristy Koenig, Kasinath Kuravi, Farzana Rahman, Lori Sorrells, Lars Burdorf, Kristina DeSmet, Daniel Warren, Leigh Peterson, Marc Lorber, David Ayares, Andrew Cameron, Kazuhiko Yamada
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract Xenotransplantation represents a possible solution to the organ shortage crisis and is an imminent clinical reality with long-term xenograft survival in pig-to-nonhuman primate (NHP) heart and kidney large animal models, and short-term succe
Externí odkaz:
https://doaj.org/article/fb29612df711444fae0734b22e8d1904