Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Akira, Shinagawa"'
Autor:
Takeshi Kobayashi, Masataka Saito, Atsuko Takeshita, Mayu Nishitake, Chiaki Imada, Takeshi Terahara, Akira Shinagawa
Publikováno v:
Fisheries Science. 86:721-728
We analyzed the bacterial flora and chemical properties of the Japanese traditional anchovy product called salted Etari, which is distributed in Nagasaki Prefecture in the western part of Japan. The pH and NaCl concentrations ranged from 6.4 to 6.6 a
Autor:
Hirofumi Nakaoka, Shigeki Mitsunaga, Kazuyoshi Hosomichi, Liou Shyh-Yuh, Taiji Sawamoto, Tsutomu Fujiwara, Naohisa Tsutsui, Koji Suematsu, Akira Shinagawa, Hidetoshi Inoko, Ituro Inoue
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60793 (2013)
The polymorphisms in the human leukocyte antigen (HLA) region are powerful tool for studying human evolutionary processes. We investigated genetic structure of Japanese by using five-locus HLA genotypes (HLA-A, -B, -C, -DRB1, and -DPB1) of 2,005 indi
Externí odkaz:
https://doaj.org/article/d7f8228b02f24ec9a80f4063b68b00b1
Autor:
Akira Shinagawa, Takeshi Kobayashi, Takeshi Terahara, Chihiro Taguchi, Kouichi Ishii, Chiaki Imada, Xuguang Wang, Yasuyuki Harada, Naoki Shigeta, Kei-ichi Shozen
Publikováno v:
Annals of Microbiology. 66:1277-1284
Histamine-producing bacteria were isolated from various types of canned salted anchovies with cooking oil, which were purchased from retail groceries over a study period of eight years. Thirty-two histamine-producing bacterial isolates were collected
Autor:
Hidetaka Sakurai, Ryoko Sawamura, Takashi Izumi, Atsushi Kurihara, Naoya Wada, Akira Shinagawa, Miho Kazui, Tomoyo Honda, Yumi Nishiya
Publikováno v:
Biopharmaceutics & Drug Disposition. 36:352-363
Loxoprofen (LX) is a prodrug-type non-steroidal anti-inflammatory drug which is used not only as an oral drug but also as a transdermal formulation. As a pharmacologically active metabolite, the trans-alcohol form of LX (trans-OH form) is generated a
Autor:
Takashi Matsuda, Chisa Wada, Naohisa Tsutsui, Shyh-Yuh Liou, Shigeo Kamitsuji, Kenkichi Sugiura, Yusuke Kuwahara, Naoyuki Kamatani, Katsuki Tsuritani, Koichi Nishimura, Seiko Endo, Tomoko Kubota, Masatoshi Masuda, Woosung Yang, Tsutomu Fujiwara, Shinji Miyoshi, Akira Shinagawa, Kenji Watanabe, Wataru Uchida, Yuki Sugaya, Kinya Okada, Koichi Hasegawa, Taiji Sawamoto, Haretsugu Hishigaki, Hisaharu Yamada, Kazuyuki Nakazono, Koji Suematsu
Publikováno v:
Journal of Human Genetics. 60:319-326
Japan Pharmacogenomics Data Science Consortium (JPDSC) has assembled a database for conducting pharmacogenomics (PGx) studies in Japanese subjects. The database contains the genotypes of 2.5 million single-nucleotide polymorphisms (SNPs) and 5 human
Autor:
Akira Shinagawa, Toshiyuki Kosaka, Mitsunori Kato, Mayumi Hayashi, Tomohiro Honda, Atsushi Yamasaki, Takuo Washio, Kazuishi Kubota
Publikováno v:
Journal of Proteomics & Bioinformatics. 10
In a clinical trial of an α-amylase inhibitor (CS-1036), which was developed for the treatment of patients with type 2 diabetes, the half-life of plasma CS-1036 concentration was prolonged with the increase of the dose level. The prolonged half-life
Publikováno v:
Molecular & Cellular Proteomics : MCP
Molecular identification of endogenous enzymes and biologically active substances from complex biological sources remains a challenging task, and although traditional biochemical purification is sometimes regarded as outdated, it remains one of the m
Autor:
Akira Shinagawa
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 44:101-105
Autor:
Koji Matsumoto, Yutaka Iigo, Minoru Inoue, Akira Shinagawa, Kazuishi Kubota, Tomomi Yoshitomi, Tsuyoshi Hirata
Publikováno v:
Gene. 629
The NONcNZO10/LtJ mouse is a polygenic model of type-2 diabetes (T2D) that shows moderate obesity and diabetes, and is regarded as a good model reflective of the conditions of human T2D. In this study, we analyzed pathological changes of pancreases w
Autor:
Hitoshi Ishizuka, Aiko Fukahori, Yuichi Sugiyama, Shinya Tokuhiro, Akira Shinagawa, Kazutaka Yoshihara, Seiko Endo, Ichiro Ieiri, Joseph R. Walker
Publikováno v:
Journal of Human Genetics. 57:531-544
It has been reported that organic anion-transporting polypeptide (OATP) 1B1, OATP1B3 and multidrug resistance-associated protein 2 are involved in the hepatobiliary transport of olmesartan. We investigated the association of SLCO1B1, SLCO1B3 and ABCC