Effects of IL-6, JAK, TNF inhibitors, and CTLA4-Ig on knee symptoms in patients with rheumatoid arthritis

Autor: Koichi Murata, Ryuji Uozumi, Takayuki Fujii, Akira Onishi, Kosaku Murakami, Hideo Onizawa, Masao Tanaka, Akio Morinobu, Shuichi Matsuda

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)

Abstract This study aims to identify factors influencing the alleviation of knee joint symptoms in patients with rheumatoid arthritis treated with biologic or target synthetic disease-modifying antirheumatic drugs (b/tsDMARDs). Among 2321 patients wh

Externí odkaz: https://doaj.org/article/553d0e00897e414b96886daff57ca5f0

Clarification of Geometric Effects on Long-term Structural Stability of Ti/Au Multi-layered Micro-cantilevers

Autor: Ryosuke Miyai, Tomoyuki Kurioka, Chun-Yi Chen, Tso-Fu Mark Chang, Akira Onishi, Parthojit Chakraborty, Katsuyuki Machida, Hiroyuki Ito, Yoshihiro Miyake, Masato Sone

Publikováno v: Micro and Nano Engineering, Vol 23, Iss , Pp 100244- (2024)

A gold micro-electro-mechanical-systems (Au-MEMS) capacitive accelerometer having Ti/Au multi-layered structures is a promising device to detect very weak accelerations, such as muscle sounds, because of the high mass density of Au. However, Au is a

Externí odkaz: https://doaj.org/article/577be7ea20e94669be40a84260b6b678

Predictive value of baseline concomitant glucocorticoid for abatacept-mediated long-term inhibition of radiographic progression: insights from the KURAMA cohort

Autor: Kosaku Murakami, Ryu Watanabe, Toshimitsu Fujisaki, Hiromu Ito, Koichi Murata, Wataru Yamamoto, Takayuki Fujii, Hideo Onizawa, Akira Onishi, Masao Tanaka, Motomu Hashimoto, Akio Morinobu

Publikováno v: Immunological Medicine, Vol 47, Iss 1, Pp 45-51 (2024)

AbstractAbatacept (ABT) is a biological disease-modifying antirheumatic drug (bDMARDs) for rheumatoid arthritis (RA) when conventional synthetic DMARDs are ineffective. We aimed to evaluate the long-term effects of ABT on joint destruction in patient

Externí odkaz: https://doaj.org/article/ba324496bec147d9996218b3323b7790

Changes in the prevalence of mental health problems during the first year of the pandemic: a systematic review and dose-response meta-analysis

Autor: Toshi A Furukawa, Edoardo G Ostinelli, Andrea Cipriani, Pim Cuijpers, Lin Ma, Akira Onishi, Tianjing Li, Georgia Salanti, Vikram Patel, Christian Kieling, Sanae Kishimoto, Ronald C Kessler, Seena Fazel, Marialena Trivella, Akira Sato, Yikang Zhu, Raman Sharma, Matthias Egger, Simone N. Vigod, Yu-Kang Tu, Tou-Yuan Tsai, Yuan-Pang Wang, Irene Bighelli, Alessandro Rodolico, Stefan Leucht, Michael Ostacher, Ian White, Virginia Chiocchia, Ethan Sahker, Rie Toyomoto, Kazufumi Yoshida, Trevor Thompson, Dongfang Wang, Jing Tian, Katharine A Smith, Gonzalo Arrondo, Meenakshi Sharma, Silviya Ralovska, Andreas D Haas, Michael A Wewege, Bartosz Helfer, Erika Kalocsanyiova, Harrison Nelson, Gandy Dolores-Maldonado, Caroline Zangani, Kenji Omae, Shimeng Dong, Shino Kikuchi, Thomy Tonia, James S W Hong, Natalie Luise Peter, Letao Sun, Aurélie M Lasserre, Alexander Holloway, Leila Darwish, Andrea Zucchetti, Amin Sharifan, Ana Cristina Solis, Antonio Vita, Carmen Concerto, Chinonso Igwesi-Chidobe, Carlos Rios-Gonzalez, Anna Ceraso, Daniel Prates Baldez, Dicle Dilay Demir, Ying-Chun Lin, Elena Invernizzi, Gabriel Henrique Beraldi, Gamze Erzin, Giulia Ottaviano, Graciela J Balbin-Ramón, Chin-Yen Ho, Helio Elkis, Yun Chen Liu, Javier Ballesteros, Johanna Schneckenburger, Jessie Jingxia Lin, Abdulkadir Usman Sambo, Lena Feber, Mattia Marchetti, Mauro Italia, Mengchang Qin, Yi-Chih Lin, Nurul Husna Salahuddin, Rossella Virgillito, Ogulcan Ciray, Sergio A Covarrubias-Castillo, Yun Hsia, Shiue-Shiuan Tu, Vidya Giri Shankar

Publikováno v: BMJ Mental Health, Vol 27, Iss 1 (2024)

Aim To describe the pattern of the prevalence of mental health problems during the first year of the COVID-19 pandemic and examine the impact of containment measures on these trends.Methods We identified articles published until 30 August 2021 that r

Externí odkaz: https://doaj.org/article/7c865ac5b5544c68b6da64e797d48ddd

Efficacy of personalized exercise program on physical function in elderly patients with rheumatoid arthritis at high risk for sarcopenia: study protocol for a randomized controlled trial

Autor: Akira Onishi, Mie Torii, Yu Hidaka, Ryuji Uozumi, Yohei Oshima, Hiroki Tanaka, Hideo Onizawa, Takayuki Fujii, Koichi Murata, Kosaku Murakami, Masao Tanaka, Shuichi Matsuda, Akio Morinobu, Hidenori Arai, Motomu Hashimoto

Publikováno v: BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-7 (2023)

Abstract Background Patients with rheumatoid arthritis (RA) are prone to muscle atrophy due to inflammatory cytokines and corticosteroid use and immobility due to joint pain and deformity. Although resistance training is effective and safe in reversi

Externí odkaz: https://doaj.org/article/aa7ad63b67794d73ba404a13557f32c7