Zobrazeno 1 - 10 of 481 pro vyhledávání: '"Akira, Kawada"'
1
Akademický článek
Role of phlebotomy in the treatment of liver damage related to erythropoietic porphyria
Autor: Satoru Hagiwara, Naoshi Nishida, Hiroshi Ida, Kazuomi Ueshima, Yasunori Minami, Masahiro Takita, Tomoko Aoki, Masahiro Morita, Hirokazu Chishina, Yoriaki Komeda, Akihiro Yoshida, Ah-Mee Park, Masako Sato, Akira Kawada, Hajime Nakano, Hiroshi Nakagawa, Masatoshi Kudo
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Liver damage affects the prognosis of patients with erythropoietic protoporphyria (EPP). However, there is no radical cure for EPP patients with severe liver damage. This study aims to investigate the effectiveness of phlebotomy in patients
Externí odkaz: https://doaj.org/article/ff53366c5a9740a3ba15f1cbdbd8fcf6
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2
Akademický článek
Transcutaneous immunization with a highly active form of XCL1 as a vaccine adjuvant using a hydrophilic gel patch elicits long-term CD8+ T cell responses
Autor: Momo Kamei, Kazuhiko Matsuo, Haruka Imanishi, Yuta Hara, Ying-Shu Quen, Fumio Kamiyama, Naoki Oiso, Akira Kawada, Naoki Okada, Takashi Nakayama
Publikováno v: Journal of Pharmacological Sciences, Vol 143, Iss 3, Pp 182-187 (2020)
Memory CD8+ cytotoxic T-lymphocytes (CTLs) play a key role in protective immunity against infection and cancer. However, the induction of memory CTLs with currently available vaccines remains difficult. The chemokine receptor XCR1 is predominantly ex
Externí odkaz: https://doaj.org/article/6de5574a618a41fa85bc6d011c3aa815
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3
Akademický článek
Ascorbic acid derivative DDH-1 ameliorates psoriasis-like skin lesions in mice by suppressing inflammatory cytokine expression
Autor: Kosuke Kitahata, Kazuhiko Matsuo, Yuta Hara, Takanori Naganuma, Naoki Oiso, Akira Kawada, Takashi Nakayama
Publikováno v: Journal of Pharmacological Sciences, Vol 138, Iss 4, Pp 284-288 (2018)
Psoriasis is a chronic inflammatory skin disease in which inflammatory cytokines play a major role in its pathogenesis. Because DDH-1, a novel amphipathic ascorbic acid derivative, has been recently shown to reduce inflammatory cytokine expression in
Externí odkaz: https://doaj.org/article/f4d11687e79a425fb42f420d6dc5c6c4
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4
Akademický článek
A CCR4 antagonist enhances DC activation and homing to the regional lymph node and shows potent vaccine adjuvant activity through the inhibition of regulatory T-cell recruitment
Autor: Shinya Yamamoto, Kazuhiko Matsuo, Daisuke Nagakubo, Shintaro Higashiyama, Keiji Nishiwaki, Naoki Oiso, Akira Kawada, Osamu Yoshie, Takashi Nakayama
Publikováno v: Journal of Pharmacological Sciences, Vol 136, Iss 3, Pp 165-171 (2018)
CCR4 is a major chemokine receptor expressed by Treg cells that downregulate immune responses. Here, we investigated the role of CCR4-mediated Treg cell recruitment in antigen-specific immune responses. CCR4-deficient mice immunized intramuscularly w
Externí odkaz: https://doaj.org/article/73c784b7f765455e82cad80058cce46a
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5
CCR4 plays a pivotal role in Th17 cell recruitment and expansion in a mouse model of rheumatoid arthritis
Autor: Tatsuma Honzawa, Kazuhiko Matsuo, Shunya Hosokawa, Mayu Kamimura, Yuichiro Kaibori, Yuta Hara, Daisuke Nagakubo, Naoki Oiso, Akira Kawada, Atsushi Otsuka, Osamu Yoshie, Takashi Nakayama
Publikováno v: International Immunology. 34:635-642
T helper 17 (Th17) cells express CC chemokine receptor 4 (CCR4) and secrete cytokines such as interleukin-17A (IL-17A) and granulocyte macrophage colony-stimulating factor (GM-CSF), while dendritic cells (DCs) produce CC chemokine ligand 22 (CCL22),
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1803620287ed91afdbd06200018d3b
https://doi.org/10.1093/intimm/dxac041
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6
Akademický článek
Fournier's gangrene that initially mimicked pubic cellulitis in an elderly woman administered a Janus kinase inhibitor, methotrexate, and prednisolone for rheumatoid arthritis
Autor: Takahiro Shiratori, Naoki Oiso, Kohei Yamauchi, Akira Kawada
Publikováno v: Journal of Cutaneous Immunology and Allergy, Vol 3, Iss 3, Pp 71-72 (2020)
This is the first reported case of FG during administration of a JAK inhibitor. The case appeared to be a less serious manifestation when first examined; however, extremely serious clinical features developed immediately after the withdrawal of TOF.
Externí odkaz: https://doaj.org/article/a45044ab3b624c0b993fb9244ed83c59
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8
Akademický článek
A Highly Active Form of XCL1/Lymphotactin Functions as an Effective Adjuvant to Recruit Cross-Presenting Dendritic Cells for Induction of Effector and Memory CD8+ T Cells
Autor: Kazuhiko Matsuo, Kosuke Kitahata, Fumika Kawabata, Momo Kamei, Yuta Hara, Shiki Takamura, Naoki Oiso, Akira Kawada, Osamu Yoshie, Takashi Nakayama
Publikováno v: Frontiers in Immunology, Vol 9 (2018)
The chemokine receptor XCR1 is known to be selectively expressed by cross-presenting dendritic cells (DCs), while its ligand XCL1/lymphotactin is mainly produced by activated CD8+ T cells and natural killer cells. Recent studies have shown that XCL1-
Externí odkaz: https://doaj.org/article/aedb6e403de447a3abb34fee31bcd202
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10
Akademický článek
Malignant Melanoma on a Thermal Burn Scar with an Interval of More Than 70 Years
Autor: Shusuke Uchida, Naoki Oiso, Kuriko Shiga, Tomohiko Narita, Akira Kawada
Publikováno v: Case Reports in Dermatology, Vol 8, Iss 2, Pp 207-209 (2016)
Cases of malignant melanoma on thermal burn scars have occasionally been reported. We report a 78-year-old Japanese female with malignant melanoma on a thermal burn scar with an interval of more than 70 years. Our case reemphasizes the importance of
Externí odkaz: https://doaj.org/article/fd5993e1de754cb7bd6b5195bfdc62ef
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