Fatal exacerbation of type B chronic hepatitis triggered by changes in relaxed circular viral DNA synthesis and virion secretion

Autor: Akio Uemura, Tetsuo Takehara, Hisashi Ishida, Akira Sasakawa, Shinjiro Yamaguchi, Hayato Hikita, Tomohide Tatsumi, Takahiro Kodama, Norio Hayashi, Satoshi Shimizu, Wei Li, Kazuhiro Katayama, Ryotaro Sakamori, Masashi Yamamoto, Takuya Miyagi, Atsushi Hosui, Kazuyoshi Ohkawa, Keisuke Kohga

Publikováno v: Biochemical and Biophysical Research Communications. 394:87-93

Virological features of fulminant liver disease-causing hepatitis B virus (HBV) have not been fully elucidated. We studied longitudinally the viruses obtained before and after fulminant liver disease in a patient with chronic HBV infection showing fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da28063d16becceef012756059ce2547
https://doi.org/10.1016/j.bbrc.2010.02.114

Dendritic cell-based vaccines suppress metastatic liver tumor via activation of local innate and acquired immunity

Autor: Akio Uemura, Akira Sasakawa, Tetsuo Takehara, Kazuyoshi Ohkawa, Shinjiro Yamaguchi, Hayato Hikita, Tomohide Tatsumi, Norio Hayashi, Keisuke Kohga, Ryotaro Sakamori

Publikováno v: Cancer Immunology, Immunotherapy. 57:1861-1869

Dendritic cell (DC)-based vaccines have been applied clinically in the setting of cancer, but tumor-associated antigens (TAAs) have not yet been enough identified in various cancers. In this study, we investigated whether preventive vaccination with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d063f770e1aa3f2f990edc7575ab7384
https://doi.org/10.1007/s00262-008-0514-5

Contents Vol. 50, 2007

Autor: Aimi Kanada, Akira Sasakawa, Zainul Muttaqin, Toshio Nakanishi, Shintaro Takaki, Fumio Tsuda, Kazuyoshi Ohkawa, Edy Zakaria, Shiomi Aimitsu, Jong-Ding Lay, Kang-Kang Guo, Sulaiman Amangongu Depamede, Suwignyo Sumoharjo, Fatemeh Fotouhi Chahooki, Takashi Moriya, Christoph Röllig, Mohsen Karimi, Gerhard Ehninger, Keiji Tsuji, R. Barrera-Rodríguez, Christoph Pöhlmann, Shunji Mishiro, Kenichi Satoh, Dirk Bandt, D. Zamora-Avila, Seung-Min Yoo, Matsuo Deguchi, Enno Jacobs, Heuiran Lee, Olaf Wunderlich, Tatsuya Kanto, Yoshiiku Kawakami, Armando Valencia-Hernández, J. Salinas-Silva, Jeonghyun Ahn, Hiroto Ishihara, Gui-Sheng Ye, S. Saavedra-Alonso, Yoo Kyum Kim, Michio Imamura, Majid Sadeghizadeh, C. Vargas-Rodarte, L. Trejo-Avila, Johannes Schetelig, Wenny Astuti Achwan, Shoichi Takahashi, Akio Uemura, Hao Xu, Masanori Kagita, Youngmee Jee, Myung-Shin Lee, Hiroiku Kawakami, P. Zapata-Benavides, Ilseon Seo, Nader Maghsoudi, Yan-Ming Zhang, Shinjiro Yamaguchi, Kazuhiro Katayama, Hiroshi Aikata, Tomohide Tatsumi, Kristina Hochauf, Farida Behzadian, Kazuaki Chayama, Xiao-Yun Yang, Efraín Garrido, Jacques Rohayem, Norio Hayashi, Junsoo Park, Natsumi Abe, C. Rodríguez-Padilla, Kazuaki Takahashi, R. Tamez-Guerra, Tetsuo Takehara, John Jenn-Yenn Lu, Eun Jung Jun, Chul Hyun Joo, Mulyanto, Donghou Kim, Hayato Hikita, Farzaneh Sabahi, Keisuke Kohga, Taegun Seo, Naoki Hiramatsu, Taizo Hijioka, Mikiya Kitamoto, Christian Cuevas-Bennett, Ryotaro Sakamori, Xiao-Ming Deng, Hai-Xia Hong

Publikováno v: Intervirology. 50:I-V

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a3c1513fd56f3eca2b87758f6ffe1c0
https://doi.org/10.1159/000119203

[Untitled]

Autor: Kazunobu ISHIBASHI, Yuko OOKA, Akio UEMURA, Sumi KIKKAWA, Shinichiro SHINZAKI, Satoshi EGAWA, Toyohiko YOKOI, Akiko NANJYO, Yoshiki ITO, Masafumi NAITO, Kazuhiro KATAYAMA, Yoshiro YAMAZAKI

Publikováno v: Kanzo. 42:144-149

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2e84f2e875c2c85f16bce6e1ea0aa46
https://doi.org/10.2957/kanzo.42.144

Human Neutrophil Elastase Degrades Inter-.ALPHA.-Trypsin Inhibitor to Liberate Urinary Trypsin Inhibitor Related Proteins

Autor: Akio Uemura, Jiro Hirose, Toshiko Ozawa, Yuji Nagao, Toshihisa Miura, Mitsuko Isaji, Atsushi Nii, Katsuaki Kato, Kazuya Yamashiro

Publikováno v: Biological and Pharmaceutical Bulletin. 21:651-656

Urinary trypsin inhibitor (UTI) is a physiological protease inhibitor and inter-alpha-trypsin inhibitor (ITI) is regarded as a precursor of UTI. The purpose of this study is to determine the mechanism of the UTI release from ITI. To examine this, ITI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee70d57f0f679f100cea88c39a5da38
https://doi.org/10.1248/bpb.21.651