Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Akio Takezaki"'
Autor:
Kazuyoshi Hosomichi, Hisatsugu Goto, Hisanori Uehara, Koji Yasutomo, Shin Ichi Tsukumo, Akio Takezaki, Julie G. Ledford, Yasuhiko Nishioka, Yasuhiro Setoguchi
Publikováno v:
The Journal of Experimental Medicine
We identify a homozygous mutation in SFTPA1 in patients with idiopathic pulmonary fibrosis (IPF). The mutation causes increased necroptosis of type II alveolar epithelial cells through the IRE1α–JNK axis, which highlights the necroptosis pathway a
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 46(6)
Lung cancer as progressive disease is often associated with a poor quality of life(QOL)which is related to a poor prognosis. We review the impact of patient-reported outcome(PRO)as an indicator of health-related QOL on the management of lung cancer p
Autor:
Hisatsugu Goto, Katsuhiro Kinoshita, Masami Kishi, Yuki Yokota, Jun Kishi, Hisanori Uehara, Keisuke Izumi, Yoshinori Aono, Momoyo Azuma, Yasuhiko Nishioka, Hiroshi Kawano, Akio Takezaki, Seidai Sato
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 51:793-801
Circulating fibrocytes have been reported to migrate into the injured lungs, and contribute to fibrogenesis via CXCL12-CXCR4 axis. In contrast, we report that imatinib mesylate prevented bleomycin (BLM)-induced pulmonary fibrosis in mice by inhibitin
Autor:
Momoyo Azuma, Hirohisa Ogawa, Saburo Sone, Masami Kishi, Jun Kishi, Hideki Makino, Yuki Yokota, Hisanori Uehara, Yoshinori Aono, Keisuke Izumi, Hiroshi Kawano, Katsuhiro Kinoshita, Akio Takezaki, Yasuhiko Nishioka
Publikováno v:
The journal of medical investigation : JMI. 60(1-2):127-137
Circulating fibrocytes had been reported to migrate into the injured lungs, and contribute to fibrogenesis via chemokine-chemokine receptor systems including CXCL12-CXCR4 axis. Here we hypothesized that blockade of CXCR4 might inhibit the migration o
Autor:
Momoyo Azuma, Katsuhiro Kinoshita, Rentsenkhand Batmunkh, Yoshinori Aono, Yasuhiko Nishioka, Akio Takezaki, Saburo Sone, Masami Kishi, Jun Kishi, Hideki Makino
Publikováno v:
The Journal of Medical Investigation. 58:188-196
Idiopathic pulmonary fibrosis is a progressive and lethal disease of the lung that is characterized by the proliferation of fibroblasts and increased deposition of the extracellular matrix. The CCN6/WISP-3 is a member of the CCN family of matricellul
Publikováno v:
Journal of the Japan Institute of Metals. 74:643-649
Dissimilar laser brazing of boron nitride ceramics and cemented carbide has been investigated by using silver-copper-titanium braze alloys with different titanium contents of up to 2.80 mass%; efficient bond strength was achieved using brazes with mo
Autor:
Katsuhiro Kinoshita, Hideki Makino, Hisanori Uehara, Momoyo Azuma, Yoshinori Aono, Saburo Sone, Yasuhiko Nishioka, Masami Kishi, Akio Takezaki, Hiroyasu Okazaki, Jun Kishi, Keisuke Izumi
Publikováno v:
American journal of respiratory cell and molecular biology. 49(4)
Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase involved in various biological functions, including cell survival, proliferation, migration, and adhesion. FAK is an essential factor for transforming growth factor β to induce myofibrobla
Autor:
Katsuhiro Kinoshita, Masami Kishi, Momoyo Azuma, Akio Takezaki, Yoshinori Aono, Shuichi Abe, Hiroyasu Okazaki, Jun Kishi, Yasuhiko Nishioka
Publikováno v:
C46. IDIOPATHIC PULMONARY FIBROSIS: PATHOGENESIS AND COMORBIDITIES.
Autor:
Akio, Takezaki, Toru, Araiz, Yoshikazu, Inoue, Akihide, Nishiyam, Masanori, Kitaichi, Seiji, Hayashi
Publikováno v:
Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society. 49(12)
A 49-year-old man consulted our hospital several days after the onset of dyspnea and was admitted because it rapidly exacerbated 9 days after presentation. Diffuse centrilobular micronodular shadows and diffuse opacities in all lung fields were noted
Autor:
Katsuhiro Kinoshita, Eiji Kawahara, Saburo Sone, Masami Kishi, Shinji Hatakeyama, Momoyo Azuma, Hisanori Uehara, Yoshinori Aono, Akio Takezaki, Yasuhiko Nishioka
Publikováno v:
D39. NOVEL THERAPEUTICS IN PULMONARY FIBROSIS.