Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Akio Monji"'
Autor:
Akio Monji, Yang Zhang, G.V. Naveen Kumar, Christelle Guillermier, Soomin Kim, Benjamin Olenchock, Matthew L. Steinhauser
Publikováno v:
Diabetes
Adipose tissue (AT) expands by a combination of two fundamental cellular mechanisms: hypertrophic growth of existing adipocytes or through generation of new adipocytes, also known as hyperplastic growth. Multiple lines of evidence suggest a limited c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ca363a48212c3c003b16cb1cb521b9
https://europepmc.org/articles/PMC8893943/
https://europepmc.org/articles/PMC8893943/
Autor:
Matthew L. Steinhauser, Benjamin Olenchock, Soomin Kim, Christelle Guillermier, G.V. Naveen Kumar, Yang Zhang, Akio Monji, Ada Admin
Adipose tissue (AT) expands by a combination of two fundamental cellular mechanisms: hypertrophic growth of existing adipocytes or through generation of new adipocytes also known as hyperplastic growth. Multiple lines of evidence suggest a limited ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f98ca81364873ca2333e8c321165a55
https://doi.org/10.2337/figshare.17296316
https://doi.org/10.2337/figshare.17296316
Autor:
Yasuko K Bando, Morihiko Aoyama, Akio Monji, Toyoaki Murohara, Kazuyuki Nishimura, Haruya Kawase
Publikováno v:
Journal of Molecular and Cellular Cardiology. 98:37-47
Background To address the impact of antidiabetic drugs on cardiovascular safety is a matter of clinical concern. Preclinical studies revealed that various protective effects of dipeptidyl peptidase-4 inhibitor (DPP4i) on cardiovascular disease; howev
Autor:
Toyoaki Murohara, Toko Mitsui, Toshimasa Shigeta, Morihiko Aoyama, Akio Monji, Yasuko K. Bando
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 305:H295-H304
Glucagon-like peptide-1 receptor (GLP-1R) agonist exendin-4 (Ex-4) is a remedy for type 2 diabetes mellitus (T2DM). Ex-4 ameliorates cardiac dysfunction induced by myocardial infarction in preclinical and clinical settings. However, it remains unclea
Publikováno v:
Circulation Research. 119
Aim: The purpose of this study is to screen the target metabolites of diabetic microangiopathy in heart by use of whole heart metabolome analysis. Methods: Diet-induced type 2 diabetic mouse were divided into two groups; control and those treated wit
Publikováno v:
Circulation. Heart failure. 9(1)
Background— Ample evidence demonstrates cardiovascular protection by incretin-based therapy using dipeptidyl peptidase 4 inhibitor (DPP4i) and glucagon-like peptide-1 (GLP-1) under either diabetic or nondiabetic condition. Their action on myocardiu
Autor:
Akio Monji, Yasuko K Bando, Haruya Kawase, Hiroyuki Nishimura, Morihiko Aoyama, Toko Mitsui, Toyoaki Murohara
Publikováno v:
Circulation. 132
Introduction: Sirtuin 3 (SIRT3) is a mitochondrial protein deacetylase and its expression is increased by fasting and exercise in skeletal muscle; however, the impact of anti-diabetic intervention on diabetic myocardium remained uncertain. Hypothesis
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 18:200-208
Aim: Diabetic peripheral artery disease (PAD) is prone to be aggressive and recent reports have demonstrated that p53 accumulation may be responsible for impaired wound healing in diabetes. Statins has been demonstrated to facilitate p53 degradation
Autor:
Akio Monji, Yasuko K Bando
Publikováno v:
Publons
Introduction: The incretin hormone glucagon-like peptide-1 (GLP-1) restores diabetic myocardial remodeling observed in type 2 diabetic mice (T2DM); however, it remains unclear whether GLP-1 may mod...
Autor:
Yasuko K Bando, Masafumi Kuzuya, Toyoaki Murohara, Morihko Aoyama, Cheng Xiangwu, Haruya Kawase, Akio Monji
Publikováno v:
Circulation. 130
Introduction: Aging causes skeletal muscle atrophy (i.e. sarcopenia). In heart, aging is also known to cause cardiac dysfunction such as diastolic dysfunction; however, the impact of aging on myocardial cell growth remains uncertain. Hypothesis: Beca