Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Akio Matsukage"'
Publikováno v:
日本女子大学紀要. 理学部 = Journal of Japan Women's University. Faculty of science. 16:1-11
Autor:
Nozomi Sugimoto, Masatoshi Fujita, Issay Kitabayashi, Satoko Osano, Akio Matsukage, Yasutoshi Tatsumi, Mako Narisawa-Saito, Tohru Kiyono, Takashi Yugawa
Publikováno v:
Molecular Biology of the Cell. 19:1007-1021
In mammalian cells, Cdt1 activity is strictly controlled by multiple independent mechanisms, implying that it is central to the regulation of DNA replication during the cell cycle. In fact, unscheduled Cdt1 hyperfunction results in rereplication and/
Autor:
Yoshihiro H. Inoue, Péter Deák, Katsuhito Ohno, Masamitsu Yamaguchi, Hideki Yoshida, Akio Matsukage, Fumiko Hirose, Yuko Hayashi
Publikováno v:
Cancer Science. 95:436-441
Ectopic expression of human p53 in Drosophila eye imaginal disc cells induces apoptosis and results in a rough eye phenotype in the adult flies. We have screened Drosophila stocks to identify mutations that enhance or suppress the p53-induced rough e
Autor:
Akio Matsukage, Akira Kakizuka, N Fujikake, Masamitsu Yamaguchi, H Higashiyama, Yoshihiro H. Inoue, Fumiko Hirose
Publikováno v:
Cell Death & Differentiation. 9:264-273
We have successfully generated a Drosophila model of human polyglutamine (polyQ) diseases by the targeted expression of expanded-polyQ (ex-polyQ) in the Drosophila compound eye. The resulting eye degeneration is progressive and ex-polyQ dosage- and e
Autor:
Fumiko Hirose, Kengo Sakaguchi, Masamitsu Yamaguchi, Yoshihiro H. Inoue, Hideki Yoshida, Akio Matsukage
Publikováno v:
Genes to Cells. 6:877-886
Background DNA replication-related element binding factor (DREF) has been suggested to be involved in regulation of DNA replication- and proliferation-related genes in Drosophila. While the effects on the mutation in the DNA replication-related eleme
Autor:
Kengo Sakaguchi, Yuko Hayashi, Fumiko Hirose, Akio Matsukage, Masahiro Yamagishi, Hideki Yoshida, Yoshihiro H. Inoue, Yoshimi Nishi, Katsuyuki Tamai, Masamitsu Yamaguchi
Publikováno v:
Chromosoma. 110:313-321
Transgenic flies were established in which ectopic expression of boundary element-associated factor (BEAF) 32A was targeted to the Drosophila eye imaginal disc. The eyes of the adult fly displayed a severe rough eye phenotype. When these eyes were se
Characterization of a Drosophila homologue of the human myelodysplasia/myeloid leukemia factor (MLF)
Autor:
Fumiko Hirose, Yasuyoshi Nishida, Akio Matsukage, Katsuhito Ohno, Osamu Taguchi, Masamitsu Yamaguchi, Yasuhiko Takahashi, Yoshihiro H. Inoue
Publikováno v:
Gene. 260:133-143
The transcription factor DREF regulates proliferation-related genes in Drosophila. With two-hybrid screening using DREF as a bait, we have obtained a clone encoding a protein homologous to human myelodysplasia/myeloid leukemia factor 1 (hMLF1). We te
Autor:
Momoki Hirai, Akio Matsukage, Yuji Nimura, Akihiro Yasui, Kyoji Ikeda, Kei-ichi Nagasawa, Kenzo Kitamura, Makoto Nakanishi
Publikováno v:
Journal of Biological Chemistry. 275:31233-31238
The BRCA1 COOH terminus (BRCT) motif is present in many nuclear proteins that contribute to cell cycle regulation or DNA repair. Polymerase chain reaction-based screening with degenerate primers targeted to the BRCT motif resulted in the isolation of
Autor:
Akio Matsukage, Naoko Nishikawa, Fumio Yatagai, Akio Sugino, Masako Izumi, Fumio Hanaoka, Masamitsu Yamaguchi, Masayuki Yokoi, Hiroshi Miyazawa, Masahiro Yamagishi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1492:341-352
We have isolated a genomic DNA fragment spanning the 5′-end of the gene encoding the catalytic subunit of mouse DNA polymerase α. The nucleotide sequence of the upstream region was G/C-rich and lacked a TATA box. Transient expression assays in cyc
Autor:
Akio Matsukage, Young-Shin Kim, Eun-Jin Oh, Masamitsu Yamaguchi, Hyun-Sook Park, Mi-Ae Yoo, Yasuyoshi Nishida, Eun-Jeong Kwon
Publikováno v:
Journal of Biological Chemistry. 275:19824-19830
The Drosophila raf (D-raf) gene promoter contains a recognition consensus sequence for Drosophila STAT (D-STAT). By band mobility shift assay, we detected a factor binding to the D-STAT-recognition sequence in extracts of cultured Drosophila cells tr