Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Akio Manabe"'
Autor:
Tatsuma Ban, Masako Kikuchi, Go R. Sato, Akio Manabe, Noriko Tagata, Kayo Harita, Akira Nishiyama, Kenichi Nishimura, Ryusuke Yoshimi, Yohei Kirino, Hideyuki Yanai, Yoshiko Matsumoto, Shuichi Suzuki, Hiroe Hihara, Masashi Ito, Kappei Tsukahara, Kentaro Yoshimatsu, Tadashi Yamamoto, Tadatsugu Taniguchi, Hideaki Nakajima, Shuichi Ito, Tomohiko Tamura
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
IRF5 is a potential target for therapy in systemic lupus erythematosus (SLE). Here the authors show using mouse SLE-like models that genetic or chemical inhibition of IRF5 after SLE onset could be more effective than, or an add on for, currently util
Externí odkaz:
https://doaj.org/article/bdb59bea8b1b42119ff3a063d9c303ba
Publikováno v:
Bioorganic & Medicinal Chemistry. :117332
Autor:
Ryusuke Yoshimi, Tadatsugu Taniguchi, Hideyuki Yanai, Shuichi Suzuki, Akira Nishiyama, Hideaki Nakajima, Tadashi Yamamoto, Shuichi Ito, Kappei Tsukahara, Yohei Kirino, Noriko Tagata, Go R. Sato, Kenichi Nishimura, Tatsuma Ban, Hiroe Hihara, Masako Kikuchi, Akio Manabe, Masashi Ito, Kentaro Yoshimatsu, Yoshiko Matsumoto, Kayo Harita, Tomohiko Tamura
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
The transcription factor IRF5 has been implicated as a therapeutic target for the autoimmune disease systemic lupus erythematosus (SLE). However, IRF5 activation status during the disease course and the effects of IRF5 inhibition after disease onset
Autor:
Koji Furukawa, Takachika Azuma, Akio Manabe, Atsuko Furukawa, Hiroyoshi Kuba, Toshihide Okajima
Publikováno v:
Molecular Immunology. 43:1751-1760
We previously found that there are two distinct antibody (Ab) maturation pathways for the immune response of C57BL/6 mice to 4-hydroxy-3-nitrophenylacetyl (NP), one involving Abs with high evolvability (group-H) and the other involving Abs with low e
Autor:
Akio Manabe
Publikováno v:
Journal of Pesticide Science. 29:245-248
Autor:
Takeshi Akita, Akio Manabe
Publikováno v:
The Proceedings of Mechanical Engineering Congress, Japan. 2015:G1900103
Autor:
Hirotaka Takano, Akio Manabe, Yoshio Hisada, Kazunori Yanagi, Shizuya Tanaka, Kunihiko Furuzawa
Publikováno v:
Bioscience, biotechnology, and biochemistry. 66(10)
Several 1-(alpha-tert-butylcinnamoyl)imidazoles were prepared to examine their fungicidal activity. The (Z)-4-chlorocinnamoyl derivative was prepared from (anti)-2-tert-butyl-3-(4-chlorophenyl)-3-hydroxypropanoic acid by treating with 1,1'-carbonyldi
Publikováno v:
Pesticide Science. 55:649-650
The four diastereomers of 2-cyano-N-[1-(2,4-dichlorophenyl)ethyl]-3,3-dimethyl-butyramide were prepared by a direct HPLC separation with chiral columns. The [(S)acid, (R)amine]-isomer was the most antifungal among the diastereomers tested. Because of
Publikováno v:
Journal of Heterocyclic Chemistry. 27:1517-1518
2-Alkylamino-4H-1,3,4-benzothiadiazines 3 are prepared in a one-pot synthesis from 1-phenyl-3-thiosemi-carbazides 1 and bromine through an oxidative cyclization.
Publikováno v:
Agricultural and Biological Chemistry. 51:1959-1965