Zobrazeno 1 - 10
of 387
pro vyhledávání: '"Akio MIYAMOTO"'
Autor:
Ihshan Akthar, Yejin Kim, Takashi Umehara, Chihiro Kanno, Motoki Sasaki, Mohamed Ali Marey, Mohamed Samy Yousef, Shingo Haneda, Masayuki Shimada, Akio Miyamoto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
It is known that sperm and seminal plasma (SP) affect uterine immunity. In cattle, artificial insemination enables breeding by depositing frozen and largely diluted sperm with a negligible amount of SP into the uterus. Thus, the present study focused
Externí odkaz:
https://doaj.org/article/42edfaa6c48d42a2b5823995e9ebc606
Autor:
Mohamed A. MAREY, Dongxue MA, Hitomi YOSHINO, Ibrahim F. ELESH, Mohammad A. ZINNAH, Mariani F. FIORENZA, Satoru MORIYASU, Akio MIYAMOTO
Publikováno v:
The Journal of Reproduction and Development, Vol 69, Iss 2, Pp 95-102 (2023)
This in vivo study aimed to investigate local and systemic immune responses induced by sperm in cows after artificial insemination (AI). Initially, 12 multiparous Japanese Black cows were subjected to intrauterine AI (AI group, n = 6) or saline infus
Externí odkaz:
https://doaj.org/article/468219c5651c4dc1886098a475ec323e
Autor:
Mohamed Aboul Ezz, Alireza Mansouri, Ihshan Akthar, Mohamed Samy Yousef, Rasoul Kowsar, Akio Miyamoto
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Recently, we reported that sperm induce cluster of differentiation 44 (CD44) expression and Toll-like receptor 2 (TLR2)-mediated inflammatory response in bovine uterus. In the present study, we hypothesized that the interaction between CD44 of bovine
Externí odkaz:
https://doaj.org/article/d9f81b503269401789a480f996b5d617
Autor:
Alireza Mansouri, Mohamed Samy Yousef, Rasoul Kowsar, Nonoka Usui, Ihshan Akthar, Akio Miyamoto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Toll-like receptor 2 (TLR2) signaling pathway is involved in the sperm-triggered uterine inflammatory response at insemination, but its precise mechanism at molecular-level remains unknown. According to the ligand specificity, TLR2 forms a heterodime
Externí odkaz:
https://doaj.org/article/420a8ae520bf40fbbac3af2cffe7ac2c
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The novel coronavirus disease (COVID-19) is currently a big concern around the world. Recent reports show that the disease severity and mortality of COVID-19 infected patients may vary from gender to gender with a very high risk of death for
Externí odkaz:
https://doaj.org/article/d8d283051a9d49f4b9954c2462ba6d69
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Upon insemination, sperm cells are exposed to components of the female reproductive tract (FRT) fluids, such as urea and epidermal growth factor (EGF). It has been shown that both urea and EGF use EGF receptor signaling and produce reactive
Externí odkaz:
https://doaj.org/article/4592629b3c244396b915aed1fcfd2028
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cumulus cells of ovulated cumulus-oocyte complexes (COCs) express Toll-like receptor 2 (TLR2), pathogen recognition receptors, to recognize and react to sperm signals during fertilization. Sperm also express TLR2, but its contribution to the sperm-oo
Externí odkaz:
https://doaj.org/article/d31be5b197bd4a138f2908278e42a7d8
Autor:
Kazuya Kusama, Mohammad B. Rashid, Rasoul Kowsar, Mohamed A. Marey, Anup K. Talukder, Kentaro Nagaoka, Masayuki Shimada, Hasan Khatib, Kazuhiko Imakawa, Akio Miyamoto
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
This study aimed to characterize proteins and exosomal microRNAs (miRNAs) in the uterine flushings (UF) of cows associated with Day 7 (D7) pregnancy using the embryo donor cows of the embryo transfer program. Superovulated cows either were inseminate
Externí odkaz:
https://doaj.org/article/35ea8c45b7eb48ad9ab6a6543213a22a
Autor:
Ibrahim Fouad Elesh, Mohamed Ali Marey, Mohammed Ali Zinnah, Ihshan Akthar, Tomoko Kawai, Fayrouz Naim, Wael Goda, Abdel Rahman A. Rawash, Motoki Sasaki, Masayuki Shimada, Akio Miyamoto
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
In mammals, the uterine mucosal immune system simultaneously recognizes and reacts to most bacteria as well as allogenic sperm mainly through the Toll-like receptors (TLR)2/4 signaling pathway. Here, we characterized the impact of pathogen-derived TL
Externí odkaz:
https://doaj.org/article/6ad1992d5c5c4732ae53ea7b0d28e7e0
Publikováno v:
Cells, Vol 11, Iss 7, p 1075 (2022)
Progesterone has been shown to be a potent suppressor of several inflammatory pathways. During pregnancy, progesterone levels increase, allowing for normal pregnancy establishment and maintenance. The dysregulation of progesterone, as well as inflamm
Externí odkaz:
https://doaj.org/article/6fdbe62bb87a4f609c25eaf112d1c5e8