Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Akio A. Awa"'
Autor:
Masao Tomonaga, Yoshiaki Kodama, Yuko Hirai, Kismet A. Cordova, Akio A. Awa, Mariko Mine, Nori Nakamura, Harry M. Cullings, Kanya Hamasaki
Publikováno v:
International Journal of Radiation Biology. 95:321-328
Purpose: Cancer risks for Nagasaki survivors once appeared to be lower than for Hiroshima survivors. The possibility that this was due to overestimation of the doses for the Nagasaki survivors was tested by measuring biological doses of Nagasaki surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4384ca6be558aeae8d86a2036164d2
https://doi.org/10.1080/09553002.2019.1552807
https://doi.org/10.1080/09553002.2019.1552807
Autor:
Yoshiaki Kodama, Nori Nakamura, Kanya Hamasaki, Yuko Hirai, Kismet A. Cordova, Harry M. Cullings, Akio A. Awa
Publikováno v:
Radiation research. 188(4)
Retrospective estimation of the doses received by atomic bomb (A-bomb) survivors by cytogenetic methods has been hindered by two factors: One is that the photon energies released from the bomb were widely distributed, and since the aberration yield v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645249e424c8b6acec3c8589edda1c01
https://pubmed.ncbi.nlm.nih.gov/28800285
https://pubmed.ncbi.nlm.nih.gov/28800285
Autor:
Mimako Nakano, Kazuo Ohtaki, Nori Nakamura, Kanya Hamasaki, F. Lagarde, Akio A. Awa, Yoshiaki Kodama
Publikováno v:
Radiation Research. 164:618-626
Radiation-induced genomic instability has been studied primarily in cultured cells, while in vivo studies have been limited. One major obstacle for in vivo studies is the lack of reliable biomarkers that are capable of distinguishing genetic alterati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ad4696d0c85d18a57ae46c01102968
https://doi.org/10.1667/rr3455.1
https://doi.org/10.1667/rr3455.1
Autor:
Mimako Nakano, Kazuo Ohtaki, Yoshiaki Kodama, John B. Cologne, Masahiro Itoh, Akio A. Awa, Nori Nakamura
Publikováno v:
Radiation Research. 161:373-379
Human fetuses are thought to be highly sensitive to radiation exposure because diagnostic low-dose X rays have been suggested to increase the risk of childhood leukemia. However, animal studies generally have not demonstrated a high radiosensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf3be6d3261863c2e822fdf4b16683c
https://doi.org/10.1667/3147
https://doi.org/10.1667/3147
Autor:
Mimako Nakano, Kazuo Ohtaki, Akio A. Awa, John B. Cologne, Yoichiro Kusunoki, Yoshiaki Kodama, Masahiro Itoh, Nori Nakamura
Publikováno v:
Radiation Research. 161:273-281
Quantifying the proliferative capacity of long-term hematopoietic stem cells in humans is important for bone marrow transplantation and gene therapy. Obtaining appropriate data is difficult, however, because the experimental tools are limited. We hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95377e7bb780313a475f65010010b4c3
https://doi.org/10.1667/rr3133
https://doi.org/10.1667/rr3133
Autor:
Yuko Hirai, Nori Nakamura, Yoichiro Kusunoki, Akio A. Awa, David J. Pawel, Mitoshi Akiyama, Seishi Kyoizumi
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 329:183-196
The mutant frequency at the hypoxanthine-guanine phosphoribosyltransferase locus in peripheral blood lymphocytes was measured for 254 atomic bomb survivors (171 exposed and 83 control survivors) by a colony assay using recombinant human interleukin-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc4c8c864ecbe9b8f109f1bd14463b3
https://doi.org/10.1016/0027-5107(95)00044-j
https://doi.org/10.1016/0027-5107(95)00044-j
Autor:
Terry C. Pellmar, Horst Romm, Pataje G. S. Prasanna, Akio A. Awa, Mitsuaki A. Yoshida, Mark S. Jenkins, Patricia K. Lillis-Hearne, Ruth C. Wilkins, C. Norman Coleman, Gordon K. Livingston, Ursula Oestreicher
Publikováno v:
Radiation research. 175(3)
Biological dosimetry is an essential tool for estimating radiation dose. The dicentric chromosome assay (DCA) is currently the tool of choice. Because the assay is labor-intensive and time-consuming, strategies are needed to increase throughput for u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::267575329e790efb04acc5d82b063631
https://pubmed.ncbi.nlm.nih.gov/21388284
https://pubmed.ncbi.nlm.nih.gov/21388284
Publikováno v:
International Journal of Radiation Biology. 64:565-569
This study was designed to test the scoring efficiency of reciprocal translocations and dicentrics induced by X-irradiation in vitro using the fluorescence in situ hybridization (FISH) technique. An excess was found in the frequencies of reciprocal t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b6363daf74c2a39d0630a8aa98e1ca
https://doi.org/10.1080/09553009314551781
https://doi.org/10.1080/09553009314551781
Autor:
Akio A. Awa
Publikováno v:
Journal of Radiation Research. 32:265-274
Current status of knowledge on the radiation-induced chromosome aberrations persisting since their induction in 1945 to date in the somatic cells of A-bomb survivors in Hiroshima and Nagasaki is reviewed. Dose-response relationship for chromosome abe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af3b96bf4b9fc7915bff68fe6ec3e2b
https://doi.org/10.1269/jrr.32.supplement_265
https://doi.org/10.1269/jrr.32.supplement_265
Autor:
Tzu-Cheg Kao, Ursula Oestreicher, Pataje G. S. Prasanna, Mitsuaki A. Yoshida, Ruth C. Wilkins, Terry C. Pellmar, Horst Romm, Akio A. Awa, Gordon K. Livingston, Mark S. Jenkins
Publikováno v:
Radiation research. 169(5)
This interlaboratory comparison validates the dicentric chromosome assay for assessing radiation dose in mass casualty accidents and identifies the advantages and limitations of an international biodosimetry network. The assay's validity and accuracy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f635621b9a42128c0ed742f0ab3f4a25
https://pubmed.ncbi.nlm.nih.gov/18439045
https://pubmed.ncbi.nlm.nih.gov/18439045