Výsledky vyhledávání - "Akinori Wakaiki"

Pharmacokinetics of SNI-2011. (1): Absorption, Distribution, Metabolism and Excretion of 14C-SNI-2011 in Rats

Autor: Shin-ichi Shimada, Makoto Niwa, Yayoi Yoshioka, Kazuhiro Kohsaka, Takashi Nogami, Kazue Nemoto, Shuichiro Tsutsumi, Takuo Washio, Takashi Kawashiro, Toshie Tomizuka, Hiroki Ebine, Atsushi Takao, Akinori Wakaiki, Yayoi Shimizu, Kouwa Yamashita, Ken-ichi Nakano, Masato Suwa

Publikováno v: Drug Metabolism and Pharmacokinetics. 16:537-552

The absorption, distribution, metabolism, excretion and plasma protein binding of SNI-2011, a novel muscarinic acetylcholine receptor agonist developed as an agent improving the symptoms of dry mouth or dry eye caused by Sjogren's syndrome, were stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b8c2139933a71137f59e819de33724d1
https://doi.org/10.2133/dmpk.16.537

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Studies on the metabolic fate of recombinant human erythropoietin(SNB-5001). II: Plasma level profiles, distribution, metabolism, excretion, accumulation in rats after intravenous and subcutaneous injection of 125I-SNB-5001

Autor: Toshie Arai, Eisuke Shimotsuga-gun Tsuda, Hiroaki Masunaga, Yasuhiro Uematsu, Masatsugu Ueda, Chitose Takahashi, Akinori Wakaiki, Kazuhiro Kohsaka, Reiko Takahira

Publikováno v: Drug Metabolism and Pharmacokinetics. 6:693-716

Pharmacokinetics and accumulation of recombinant human erythropoietin (SNB-5001) were studied in rats after the intravenous(i.v.) and subcutaneous injection(s.c.) of 125I-SNB-5001. Plasma level declined biexponentially with a rapid phase (t1/2α : 0.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68e3065ff92d60e0e9c4cadd44679e37
https://doi.org/10.2133/dmpk.6.693

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Dissociation of a glucan fraction (CO-1) from protein-bound polysaccharide of Cordyceps ophioglossoides and analysis of its antitumor effect

Autor: Akinori Wakaiki, Kohji Tamura, Gosei Kawanishi, Toshihiro Ohmori, Toshiro Yadomae, Kikuo Nomoto, Sumiaki Tsuru

Publikováno v: Chemicalpharmaceutical bulletin. 36(11)

A glucan moiety (CO-1) was dissociated from the antitumor protein-bound polysaccharide (SN-C) obtained from the culture of Cordyceps ophioglossoides by ultrasonication and heat treatment.CO-1 exhibited antitumor activity against murine sarcoma 180 wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84a5506003b48618ca115b82120244c
https://pubmed.ncbi.nlm.nih.gov/3246019

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