Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Akinori Tokito"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2749 (2024)
Vascular endothelial growth factor (VEGF) induces monocyte chemoattractant protein-1 (MCP-1) and plays an important role in vascular inflammation and atherosclerosis. We investigated the mechanisms of VEGF-induced MCP-1 expression and the effects of
Externí odkaz:
https://doaj.org/article/b3c95aca25ec4bd59df58d07796258f5
Autor:
Katsuyuki Umebashi, Masayoshi Yamamoto, Akinori Tokito, Ku Sudou, Yoko Takenoshita, Michihisa Jougasaki
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 13015 (2023)
An alarmin, interleukin (IL)-33 is a danger signal that causes inflammation, inducing chemotactic proteins such as monocyte chemoattractant protein (MCP)-1 in various cells. As statins have pleiotropic actions including anti-inflammatory properties,
Externí odkaz:
https://doaj.org/article/88b044317b414769afcdbbf810c98a0f
Publikováno v:
Journal of Medical Case Reports, Vol 14, Iss 1, Pp 1-7 (2020)
Abstract Background Neurofibromatosis type 1 is characterized by multiple café au lait spots and cutaneous and plexiform neurofibromas, and is one of the most common autosomal dominant hereditary disorders caused by mutations of the neurofibromatosi
Externí odkaz:
https://doaj.org/article/361d039546974f76a25629ced2288a55
Autor:
Nami Kojima, Nobuyuki Koriyama, Akinori Tokito, Kazuma Ogiso, Koshi Kusumoto, Satoshi Kubo, Yoshihiko Nishio
Publikováno v:
BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-7 (2020)
Abstract Background The prevalence of childhood-onset growth hormone (GH) deficiency (GHD) is estimated to be approximately 1 in 5000 or more, with the cause unknown in most cases (idiopathic isolated GHD). However, additional disorders of secretion
Externí odkaz:
https://doaj.org/article/eb0a303c953346739c42dcbe50e35e5c
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191659 (2018)
Interleukin (IL)-33 is a member of the IL-1 cytokine family with dual functions as a traditional cytokine and as a transcriptional regulator. We recently reported that IL-33 up-regulated growth regulated oncogene (GRO)-α/CXCL1 expression in human va
Externí odkaz:
https://doaj.org/article/65274b3f7662448ab4c80b6bed5b913d
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68801 (2013)
Rupture of an atherosclerotic plaque is a key event in the development of cardiovascular disorders, in which matrix metalloproteinase-1 (MMP-1) plays a crucial role by degradation of extracellular matrix resulting in plaque instability. Cardiotrophin
Externí odkaz:
https://doaj.org/article/47b4ffaed4444fd7ac287aa3ad3ac7be
Autor:
Akinori Tokito, Michihisa Jougasaki
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 7, p 1178 (2016)
The matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases belonging to the metzincin superfamily. There are at least 23 members of MMPs ever reported in human, and they and their substrates are widely expressed in many tissues. Recent gr
Externí odkaz:
https://doaj.org/article/cc61767c1ed64c3e832ac81860141de8
Publikováno v:
Diabetol Int
BACKGROUND: In general, basal insulin targets fasting plasma glucose (FPG) levels, and prandial insulin targets postprandial glucose (PPG) levels. However, the effects of basal insulin on PPG levels are controversial. We investigated the effect of ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1573637c7ac4c4fd0b35368b00f0881
https://doi.org/10.1007/s13340-020-00457-3
https://doi.org/10.1007/s13340-020-00457-3
Autor:
Kazuma Ogiso, Satoshi Kubo, Nobuyuki Koriyama, Yoshihiko Nishio, Akinori Tokito, Koshi Kusumoto, Nami Kojima
Publikováno v:
BMC Endocrine Disorders
BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-7 (2020)
BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-7 (2020)
BackgroundThe prevalence of childhood-onset growth hormone (GH) deficiency (GHD) is estimated to be approximately 1 in 5000 or more, with the cause unknown in most cases (idiopathic isolated GHD). However, additional disorders of secretion of other p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c905c5d55e4a7dd9dfbc5eebe7b27f5
https://doi.org/10.1186/s12902-020-0536-3
https://doi.org/10.1186/s12902-020-0536-3
Publikováno v:
Archives of Clinical and Medical Case Reports.
We describe a 51-year-old man with type 2 diabetes and hepatic dysfunction with suspected nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH). No liver biopsy was performed. His blood test showed a decrease in platelet count
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1215f850c6a1d1a2737ced45cb0403f
https://doi.org/10.26502/acmcr.96550199
https://doi.org/10.26502/acmcr.96550199