Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Akinori Soejima"'
Publikováno v:
Clinical Nephrology. 82:320-325
Aims Human mercaptalbumin (HMA) acts as a covalent-carrier protein for sulfur-containing amino acids, cysteine, and glutathione. In addition, its sulfhydryl residue reacts with peroxyl radicals. In this study, we evaluated the redox state of human se
Autor:
Akinori Soejima, Tadahide Kuroda, Kimimasa Nakabayashi, Makiho Sekiuchi, Akira Yamada, Tetsuya Endo
Publikováno v:
Clinical and Experimental Nephrology. 10:253-261
Various glomerular diseases progress to end-stage renal failure due to an accumulation of the mesangial matrix (MM) and a thickening of the glomerular basement membrane (GBM). Both the MM and GBM are consistently metabolized through the synthesis and
Autor:
Tomoya Hayashi, Akinori Soejima, Seiichi Era, Toshihiko Nagasawa, Akira Yamada, Kazuhito Fukuoka, Takako Ootsuka, Rio Kimura, Naoki Matsuzawa
Publikováno v:
Blood Purification. 22:525-529
Background:Persistent hypoalbuminemia is a predictor of death in long-term maintenance hemodialysis patients, although cardiovascular diseases remain the leading cause of death. A decreased serum antioxidant activity in maintenance hemodialysis patie
Autor:
Ken Yoshihara, Zin Kasahara, Toshihiko Nagasawa, Yasushi Nakamoto, Kimimasa Nakabayashi, Masayuki Waku, Yoshihiro Arimura, Tsunee Yamato, Naoki Matsuzawa, Akinori Soejima
Publikováno v:
Nihon Toseki Igakkai Zasshi. 34:49-54
Autor:
Toshihiko Nagasawa, Suzuki M, Ishizuka S, Akinori Soejima, Nobuyuki Miyake, Kazuhito Fukuoka, Yasushi Kamiya
Publikováno v:
Nephron Experimental Nephrology. 8:84-90
We have previously demonstrated that gentamicin-induced acute renal failure is mediated by the consumption of renal glutathione (GSH) and accumulation of oxidized phospholipids in tubular epithelial cells as a result of inhibition of phospholipase A2
Autor:
Akinori Soejima, Masayuki Waku, Toshihiko Nagasawa, Kiyoshi Kitamoto, Nobuyuki Miyake, Naoki Matsuzawa, Yasushi Kamiya, Kazuhito Fukuoka
Publikováno v:
Clinical and Experimental Nephrology. 2:142-150
Background Acute renal failure frequently occurs as a complication of multiple organ dysfunction syndrome (MODS). Various forms of therapy for MODS, including endotoxin absorption and anticytokine therapy, have been attempted.
Autor:
Akinori Soejima, Toshihiko Nagasawa, Yasushi Kamiya, Ishizuka S, Fumika Kaneda, Masayuki Waku
Publikováno v:
American Journal of Nephrology. 21:63-65
A 71-year-old male undergoing hemodialysis for chronic renal failure presented with proximal muscle weakness. He had normal levels of serum creatine phosphokinase. The results of nerve conduction velocity studies and a needle-exploration electromyogr
Autor:
Yoshifumi, Suzuki, Yuko, Aoki, Yukie, Matsuyama, Hiroshi, Hasegawa, Yoshihiko, Shinohara, Takao, Hashimoto, Seiichi, Era, Akinori, Soejima
Publikováno v:
Nihon Jinzo Gakkai shi. 50(4)
We examined the relationship between change in the redox state of the plasma albumin molecule and the metabolic disorder of sulfur amino acid observed being accompanied by reduction of renal function. Thirty-seven cases of pre-dialysis renal failure
Publikováno v:
Analytical biochemistry. 378(1)
Current conventional measurement of allantoin levels in human serum uses an HPLC method. However, performing this assay is time-consuming and sample-intensive, and it requires expensive equipment. We have developed a novel enzyme cycling method for m
Autor:
Hideaki Nakayama, Takashi Furuta, Mari Tsuchiya, Hiromi Shibasaki, Akinori Soejima, Yasuji Kasuya, Toshihiko Nagasawa, Akira Yamada
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 870(2)
Individual variability of the pharmacokinetics of prednisolone based on the unbound concentration in plasma is of significant clinical consideration. The unbound concentrations of prednisolone were measured in 10 patients with nephrotic syndrome, two