Discrete Survival Model Analysis of Plasmodium falciparum Response to Artemisinin-Based Combination Therapies among Children in Regions of Varying Malaria Transmission in Cameroon

Autor: Akindeh M. Nji, Innocent M. Ali, Peter Thelma Ngwa Niba, Evehe Marie-Solange, Christian Heumann, Guenter Froeschl, Wilfred F. Mbacham

Publikováno v: Pathogens, Vol 10, Iss 9, p 1106 (2021)

The need to monitor changes in parasite clearance following treatment with artemisinin-based combination therapies (ACTs) is important in the containment of drug resistance. This study aimed to model Plasmodium falciparum response to ACTs among child

Externí odkaz: https://doaj.org/article/b29366f4538c48329be3a77b9850b945

Adverse Drug Reactions Associated with CYP 2B6 Polymorphisms in HIV/AIDS-Treated Patients in Yaoundé, Cameroon

Autor: Céline Nguefeu Nkenfou, Wilfred Fon Mbacham, Calvino Tah Fomboh, Charles Kouanfack, Akindeh M. Nji, Carine Nguefeu Nkenfou, Barbara Atogho Tiedeu, Jean Paul Chedjou

Publikováno v: The Application of Clinical Genetics. 12:261-268

Purpose The metabolism of antiretroviral drugs is subject to individual variations of the CYP 2B6 gene. The objective of this study was to evaluate the prevalence of CYP 2B6 516 G>T and 983 T>C polymorphisms and investigate their association with the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::23393166d2e7b3b573e0e2c8d5c69fe1
https://doi.org/10.2147/tacg.s226318

Diagnostic Accuracy of CareStart™ Malaria HRP2 and SD Bioline Pf/PAN for Malaria in Febrile Outpatients in Varying Malaria Transmission Settings in Cameroon

Autor: Jacob Chefor Bonkum, Wilfred Fon Mbacham, Guenang Kenfack Carole, Agni Efon, Marcel N. Moyeh, Jean-Paul Chedjou Kengne, Valery Pacome Kom Tchuenkam, Innocent Mbulli Ali, Dorothy Fosah Achu, Calvino Tah, Jude D. Bigoga, Akindeh M. Nji, Solange Dabou

Publikováno v: Diagnostics, Vol 11, Iss 1556, p 1556 (2021)
Diagnostics
Volume 11
Issue 9

Background: There was an increase in the number of malaria cases in Cameroon in 2018 that could reflect changes in provider practice, despite effective interventions. In this study, we assessed the diagnostic performance of two malaria rapid diagnost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f3e614a675a1bbdada4afa330b9905
https://www.mdpi.com/2075-4418/11/9/1556

Drug resistance markers within an evolving efficacy of anti-malarial drugs in Cameroon: a systematic review and meta-analysis (1998–2020)

Autor: Palmer Masumbe Netongo, Jude D. Bigoga, Anthony Ajua, Alexis Tourgordi, Wilfred Fon Mbacham, Jean Paul Chedjou, Akindeh M. Nji, Innocent Mbulli Ali, Barbara Atogho-Tiedeu, Olivia A. Achonduh-Atijegbe, Carole Else Eboumbou Moukoko, Pascal Ringwald, Oliva Ebie Ndum, Marcel N. Moyeh, Rose G. F. Leke, Dorothy A. Fosah, Rosine Djokam-Dadjeu, Fon Abongwa Acho, Eric A. Achidi, Peter Thelma Ngwa Niba, Esther Tallah, Cyrille Mbanwi Mbu’u, Marie-Solange Evehe, Randolph Ngwafor, Michael Alifrangis, Lesley Ngum Ngum

Publikováno v: Niba, P T N, Nji, A M, Evehe, M-S, Ali, I M, Netongo, P M, Ngwafor, R, Moyeh, M N, Ngum, L N, Ndum, O E, Acho, F A, Mbu'u, C M, Fosah, D A, Atogho-Tiedeu, B, Achonduh-Atijegbe, O, Djokam-Dadjeu, R, Chedjou, J P K, Bigoga, J D, Moukoko, C E E, Ajua, A, Achidi, E, Tallah, E, Leke, R G F, Tourgordi, A, Ringwald, P, Alifrangis, M & Mbacham, W F 2021, ' Drug resistance markers within an evolving efficacy of anti-malarial drugs in Cameroon : a systematic review and meta-analysis (1998-2020) ', Malaria Journal, vol. 20, 32 . https://doi.org/10.1186/s12936-020-03543-8
Malaria Journal, Vol 20, Iss 1, Pp 1-20 (2021)
Malaria Journal

Background Malaria remains highly endemic in Cameroon. The rapid emergence and spread of drug resistance was responsible for the change from monotherapies to artemisinin-based combinations. This systematic review and meta-analysis aimed to determine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6fe37c1d6b43b672f9b8d0bffee2c9
https://doi.org/10.1186/s12936-020-03543-8

Additional file 7 of Drug resistance markers within an evolving efficacy of anti-malarial drugs in Cameroon: a systematic review and meta-analysis (1998–2020)

Autor: Niba, Peter Thelma Ngwa, Akindeh M. Nji, Marie-Solange Evehe, Ali, Innocent M., Netongo, Palmer Masumbe, Ngwafor, Randolph, Moyeh, Marcel N., Ngum, Lesley Ngum, Ndum, Oliva Ebie, Fon Abongwa Acho, Mbu’u, Cyrille Mbanwi, Fosah, Dorothy A., Atogho-Tiedeu, Barbara, Achonduh-Atijegbe, Olivia, Djokam-Dadjeu, Rosine, Chedjou, Jean Paul Kengne, Bigoga, Jude D., Moukoko, Carole Else Eboumbou, Ajua, Anthony, Achidi, Eric, Tallah, Esther, Leke, Rose G. F., Tourgordi, Alexis, Ringwald, Pascal, Alifrangis, Michael, Mbacham, Wilfred F.

Additional file 7. Haplotype analyses of anti-malarial drug resistance mutant allele frequencies reported in Cameroon.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30906f195b4b75d0b35b417a12297526