Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Akinchan Kumar"'
Autor:
Muhammad Zaeem Noman, Irene Adelaide Bocci, Manale Karam, Kris Van Moer, Manon Bosseler, Akinchan Kumar, Guy Berchem, Christian Auclair, Bassam Janji
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Harmine is a dual-specificity tyrosine-regulated kinase 1A (DYRK1A) inhibitor that displays a number of biological and pharmacological properties. Also referred to as ACB1801 molecule, we have previously reported that harmine increases the presentati
Externí odkaz:
https://doaj.org/article/d3916eff71a8457593b72dfca6856050
Autor:
Meriem Hasmim, Malina Xiao, Kris Van Moer, Akinchan Kumar, Alexandra Oniga, Michel Mittelbronn, Caroline Duhem, Anwar Chammout, Guy Berchem, Jean Paul Thiery, Marianna Volpert, Brett Hollier, Muhammad Zaeem Noman, Bassam Janji
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Triple-negative subtype of breast cancer (TNBC) is hallmarked by frequent disease relapse and shows highest mortality rate. Although PD-1/PD-L1 immune checkpoint blockades have recently shown promising clinical benefits, the overall response rate rem
Externí odkaz:
https://doaj.org/article/35d1f9ea5edc46af8039bc9506e5c176
Autor:
Eric D. Wieben, Vinod Kumar Yadav, Ram Krishna Thakur, Aradhita Baral, Tapas K. Kundu, Raj K. Pandita, Bruce W. Eckloff, Shantanu Chowdhury, Tej K. Pandita, Ankita Singh, Rashi Halder, Akinchan Kumar, Mohammad Parwez Alam
Publikováno v:
Nucleic Acids Research
Previous studies have analyzed patterns of transcription, transcription factor (TF) binding or mapped nucleosome occupancy across the genome. These suggest that the three aspects are genetically connected but the cause and effect relationships are st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef2c000652723d804fd8937b717b203
https://doi.org/10.1093/nar/gku596
https://doi.org/10.1093/nar/gku596
Autor:
Vinod Kumar Yadav, Ram Krishna Thakur, Suruchi Aggarwal, Subrata Pore, Jerald Mahesh Kumar, Rajkumar Banerjee, Akinchan Kumar, Anita Mann, Maneesh Kumar, Sumitabho Deb Roy, Shantanu Chowdhury
Publikováno v:
Nucleic Acids Research
Building molecular correlates of drug resistance in cancer and exploiting them for therapeutic intervention remains a pressing clinical need. To identify factors that impact drug resistance herein we built a model that couples inherent cell-based res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fcb9c81cc1bf09f1c1d567c46f41e19
https://doi.org/10.1093/nar/gkt946
https://doi.org/10.1093/nar/gkt946
Autor:
Richa Basundra, Anh Tuân Phan, Anjali Verma, Akinchan Kumar, Samir Amrane, Shantanu Chowdhury
Publikováno v:
FEBS Journal. 277:4254-4264
G-quadruplex motifs constitute unusual DNA secondary structures formed by stacking of planar hydrogen-bonded G-tetrads. Recent genome-wide bioinformatics and experimental analyses have suggested the interesting possibility that G-quadruplex motifs co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37bbd6a174c486164d18e1c6de7da66c
https://doi.org/10.1111/j.1742-4658.2010.07814.x
https://doi.org/10.1111/j.1742-4658.2010.07814.x
Publikováno v:
Nucleic Acids Research
Guanine-rich DNA of a particular sequence adopts four-stranded structural forms known as G-quadruplex or G4 DNA. Though in vitro formation of G4 DNA is known for several years, in vivo presence of G4 DNA was only recently noted in eukaryote telomeres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d833dd453eeca6037676ecd41976ca
http://europepmc.org/articles/PMC2715224
http://europepmc.org/articles/PMC2715224
Autor:
Debabrata Mukhopadhyay, M. J. Mahesh Kumar, Vinod Kumar Yadav, Ram Krishna Thakur, Dhurjhoti Saha, Luke H. Hoeppner, Alfonso Baldi, Anirban Kar, Richa Basundra, Aradhita Baral, Pankaj Kumar, Rajkumar Banerjee, Akinchan Kumar, Gunjan Purohit, Bruno Vincenzi, Rashi Halder, Krishnendu Pal, Viji Shridhar, Laura Lorenzon, Pramod Kumar, Shantanu Chowdhury, Ankita Singh
Publikováno v:
Nucleic Acids Research
Tumor metastasis refers to spread of a tumor from site of its origin to distant organs and causes majority of cancer deaths. Although >30 metastasis suppressor genes (MSGs) that negatively regulate metastasis have been identified so far, two issues a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578443f5daa829a88e0c5c8b8b305595
https://pubmed.ncbi.nlm.nih.gov/25249619
https://pubmed.ncbi.nlm.nih.gov/25249619
Autor:
Shantanu Chowdhury, Praveen Kumar, Akinchan Kumar, Kangkan Halder, Anjali Verma, Anirban Kar, Richa Basundra, Ram Krishna Thakur, Jean-Luc Parent
Publikováno v:
Nucleic Acids Research
Regulatory influence of the G-quadruplex or G4 motif present within the nuclease hypersensitive element (NHE) in the promoter of c-MYC has been noted. On the other hand, association of NM23-H2 to the NHE leads to c-MYC activation. Therefore, NM23-H2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f75e061ae1b0b8e6ee433670438c8e2
https://pubmed.ncbi.nlm.nih.gov/19033359
https://pubmed.ncbi.nlm.nih.gov/19033359
Autor:
Yadav, Vinod Kumar, Thakur, Ram Krishna, Eckloff, Bruce, Baral, Aradhita, Singh, Ankita, Halder, Rashi, Akinchan Kumar, Mohammad Parwez Alam, Kundu, Tapas K., Pandita, Raj, Pandita, Tej K., Wieben, Eric D., Chowdhury, Shantanu
Publikováno v:
Nucleic Acids Research; Sep2014, Vol. 42 Issue 15, p9602-9611, 10p, 1 Diagram, 4 Graphs
Autor:
Aradhita Baral, Ankita Singh, Vinod Kumar Yadav, Ram Krishna Thakur, Shantanu Chowdhury, Akinchan Kumar, Rajkumar Banerjee, Krishnendu Pal, M. J. Mahesh Kumar, Anirban Kar, Pankaj Kumar, Richa Basundra, Rashi Halder
Publikováno v:
Molecular Cytogenetics
The mechanism of action of NME2, a widely accepted metastasis-suppressor gene, is poorly understood. Recently we found that NME2 directly regulates transcription of the c-MYC proto-oncogene. This prompted a genome-wide study to ascertain whether NME2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c2664663344df8a0a2977152697107