Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Akinari Sugauchi"'
Autor:
Sena Zeynep Usta, Toshihiro Uchihashi, Shingo Kodama, Kyoko Kurioka, Toshihiro Inubushi, Takuya Shimooka, Akinari Sugauchi, Soju Seki, Susumu Tanaka
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17282 (2023)
Immune checkpoint inhibitors (ICIs), including anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and anti-programmed death-1 (PD-1) antibodies, have initiated a new era in the treatment of malignant melanoma. ICIs can be used in various setti
Externí odkaz:
https://doaj.org/article/1122173deb73423f81bf9190c2778b5c
Autor:
Toshihiro Uchihashi, Hirokazu Nakahara, Hiroshi Fukuhara, Miwako Iwai, Hirotaka Ito, Akinari Sugauchi, Minoru Tanaka, Mikihiko Kogo, Tomoki Todo
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss , Pp 388-398 (2021)
The prognosis of oral squamous cell carcinoma (OSCC) largely depends on the control of lymph node metastases. We evaluate the therapeutic efficacy of G47Δ, a third-generation oncolytic herpes simplex virus type 1 (HSV-1), in mouse tongue cancer mode
Externí odkaz:
https://doaj.org/article/5067a5a625a94b2fb44a0680837a8d04
Autor:
Akinori TAKESHITA, Toshihiro UCHIHASHI, Akinari SUGAUCHI, Kyoko KURIOKA, Hitomi KAJIKAWA, Narikazu UZAWA
Publikováno v:
Japanese Journal of Oral and Maxillofacial Surgery. 69:150-157
Publikováno v:
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 35:56-59
Autor:
Shun Kasahara, Toshihiro Uchihashi, Toshihiro Inubushi, Kyoko Kurioka, Akinari Sugauchi, Kazuaki Miyagawa, Mikihiko Kogo, Susumu Tanaka
BackgroundOral squamous cell carcinoma (OSCC) progression is accompanied by bone invasion. Therefore, maintaining oral function is necessary to regulate tumor progression. Also, interleukin-12 (IL-12), a well-known anti-tumor cytokine, can suppress o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d59b1a18f1e27f32774b20634399ecf8
https://doi.org/10.1101/2023.05.26.542415
https://doi.org/10.1101/2023.05.26.542415
Autor:
Susumu Tanaka, Yu Usami, Katsutoshi Hirose, Shin-ichiro Hiraoka, Mikihiko Kogo, Toshihiro Uchihashi, Shingo Kodama, Akinari Sugauchi
Publikováno v:
World Journal of Clinical Cases
BACKGROUND Salivary duct carcinoma (SDC) is a rare, extremely aggressive malignancy that arises in the submandibular gland. It can metastasize locally early and therefore is an important differential diagnosis of metastatic disease in cervical lymph
Autor:
Kazuki Takahashi, Katarzyna A. Podyma-Inoue, Maki Saito, Shintaro Sakakitani, Akinari Sugauchi, Keita Iida, Sadahiro Iwabuchi, Daizo Koinuma, Kyoko Kurioka, Toru Konishi, Susumu Tanaka, Atsushi Kaida, Masahiko Miura, Shinichi Hashimoto, Mariko Okada, Toshihiro Uchihashi, Kohei Miyazono, Tetsuro Watabe
Publikováno v:
Cell reports. 40(13)
Transforming growth factor β (TGF-β) increases epithelial cancer cell migration and metastasis by inducing epithelial-mesenchymal transition (EMT). TGF-β also inhibits cell proliferation by inducing G1 phase cell-cycle arrest. However, the correla
Autor:
Toshihiro Inubushi, Hitomi Takahashi, Shingo Kodama, Kazuki Takahashi, Akinari Sugauchi, Mikihiko Kogo, Kyoko Kurioka, Tetsuro Watabe, Toshihiro Uchihashi, Susumu Tanaka, Katarzyna Α. Podyma‑Inoue
Publikováno v:
Oncology Reports
Melanoma is an aggressive type of cancer originating from the skin that arises from neoplastic changes in melanocytes. Transforming growth factor-β (TGF-β) is a pleiotropic cytokine and is known to contribute to melanoma progression by inducing the
Autor:
Kyoko Kurioka, Akinari Sugauchi, Susumu Tanaka, Kazuma Harada, Toshihiro Uchihashi, Soju Seki, Saori Yamada, Mikihiko Kogo
Publikováno v:
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 31:254-257
Compound odontoma, a benign epithelial odontogenic tumor, manifests disordered clinical and pathological features due to the formation of a variant tooth-like structure; moreover, it is frequently associated with disrupted permanent tooth eruption, w
Autor:
Akinari Sugauchi, Yasuhiro Yoshimatsu, Katarzyna A. Inoue, Susumu Tanaka, Tetsuro Watabe, Maki Saito, Masahiko Miura, Kazuki Takahashi, Atsushi Kaida, Mikihiko Kogo, Toshihiro Uchihashi
Publikováno v:
Cancer Research. 80:PO-040
Cancer cells forming primary tumors are heterogeneous and respond in various ways to the stimuli from tumor microenvironment. Transforming growth factor-β (TGF-β) has been implicated in progression of various types of epithelial cancer. TGF-β is k