Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Akina Hoshino"'
Autor:
Akshayalakshmi Sridhar, Akina Hoshino, Connor R. Finkbeiner, Alex Chitsazan, Li Dai, Alexandra K. Haugan, Kayla M. Eschenbacher, Dana L. Jackson, Cole Trapnell, Olivia Bermingham-McDonogh, Ian Glass, Thomas A. Reh
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1644-1659.e4 (2020)
Summary: To study the development of the human retina, we use single-cell RNA sequencing (RNA-seq) at key fetal stages and follow the development of the major cell types as well as populations of transitional cells. We also analyze stem cell (hPSC)-d
Externí odkaz:
https://doaj.org/article/301d277002ca428997541036a5fd4375
Autor:
Jing Huang, Wan-Qing Yu, Akina Hoshino, Fred Rieke, Chi Zhang, Thomas A. Reh, Rachel O.L. Wong
Publikováno v:
Journal of Comparative Neurology. 527:174-186
Choline acetyltransferase (ChAT) expressing retinal amacrine cells are present across vertebrates. These interneurons play important roles in the development of retinal projections to the brain and in motion detection, specifically in generating dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa079d31f15210791af89f749fbbd950
https://doi.org/10.1002/cne.24405
https://doi.org/10.1002/cne.24405
Autor:
Thomas A. Reh, Rachel O.L. Wong, Chi Zhang, Ana R. Silverstein, Yeon Jin Kim, Akina Hoshino, Dennis M. Dacey
Publikováno v:
Neuron
The human visual pathway is specialized for the perception of fine spatial detail. The neural circuitry that determines visual acuity begins in the retinal fovea, where the resolution afforded by a dense array of cone photoreceptors is preserved in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72fca9cda9fd1791750043de12483e2c
https://doi.org/10.1016/j.neuron.2020.09.014
https://doi.org/10.1016/j.neuron.2020.09.014
Autor:
Ian A. Glass, Thomas A. Reh, Cole Trapnell, Li Dai, Akshayalakshmi Sridhar, Dana Jackson, Olivia Bermingham-McDonogh, Akina Hoshino, Connor Finkbeiner, Alexandra K. Haugan, Kayla M. Eschenbacher, Alex Chitsazan
Publikováno v:
Cell reports
Cell Reports, Vol 30, Iss 5, Pp 1644-1659.e4 (2020)
Cell Reports, Vol 30, Iss 5, Pp 1644-1659.e4 (2020)
SUMMARY To study the development of the human retina, we use single-cell RNA sequencing (RNA-seq) at key fetal stages and follow the development of the major cell types as well as populations of transitional cells. We also analyze stem cell (hPSC)-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c24dc14e47a4ae14da2e7fad8f44338
http://europepmc.org/articles/PMC7901645
http://europepmc.org/articles/PMC7901645
Publikováno v:
Stem Cells. 33:2674-2685
During early patterning of the neural plate, a single region of the embryonic forebrain, the eye field, becomes competent for eye development. The hallmark of eye field specification is the expression of the eye field transcription factors (EFTFs). E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274bbe7d134df45627b8fb7490c87b62
https://doi.org/10.1002/stem.2062
https://doi.org/10.1002/stem.2062
Autor:
Akina Hoshino, Matthew S. Wilken, Rinki Ratnapriya, Ian A. Glass, Matthew Brooks, Olivia Bermingham-McDonogh, Vijender Chaitankar, Thomas A. Reh, Rachel O.L. Wong, Chi Zhang, Anna La Torre, Anand Swaroop, Ashley Walton, Mario Nishio, Olivia Bates, Linn Gieser, Margaret R. Starostik
Publikováno v:
Developmental cell. 43(6)
Clinical and genetic heterogeneity associated with retinal diseases makes stem-cell-based therapies an attractive strategy for personalized medicine. However, we have limited understanding of the timing of key events in the developing human retina, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b74b4fe95f1b11183389ff9664f849
https://pubmed.ncbi.nlm.nih.gov/29233477
https://pubmed.ncbi.nlm.nih.gov/29233477
Autor:
Akina Hoshino, Iris Lindberg
Publikováno v:
Colloquium Series on Neuropeptides. 1:1-112
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98a08ac8c7bdacc949cf75b05d7a3aa7
https://doi.org/10.4199/c00050ed1v01y201112npe001
https://doi.org/10.4199/c00050ed1v01y201112npe001
Autor:
Maureen Neitz, Abbi L. Engel, Akina Hoshino, Thomas A. Reh, Anu Jayabalu, Russell J. Taylor, Jennifer R Chao, Deepak A. Lamba, Jay Neitz, Anna La Torre, Ruikang K. Wang, Todd R. Klesert, Thomas Khuu
Publikováno v:
Translational Vision Science & Technology
Author(s): Chao, Jennifer R; Lamba, Deepak A; Klesert, Todd R; Torre, Anna La; Hoshino, Akina; Taylor, Russell J; Jayabalu, Anu; Engel, Abbi L; Khuu, Thomas H; Wang, Ruikang K; Neitz, Maureen; Neitz, Jay; Reh, Thomas A | Abstract: PURPOSE:Previous st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f9ab37bc2c9466e32e330757938bbd
https://doi.org/10.1167/tvst.6.3.4
https://doi.org/10.1167/tvst.6.3.4
Autor:
Akina Hoshino, Iris Lindberg
The prohormone convertases (PC) 1/3 and 2 are calcium-activated eukaryotic subtilisins with low pH optima which accomplish the limited proteolysis of peptide hormone precursors within neurons and endocrine cells. In this lecture, we review the bioche
Neurodegenerative diseases such as Alzheimer's disease (AD) are characterized by an abnormal aggregation of misfolded beta-sheet rich proteins such as β-amyloid (Aβ). Various ubiquitously expressed molecular chaperones control the correct folding o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19e7274931098c32f997b59f6d577fc
https://europepmc.org/articles/PMC3946950/
https://europepmc.org/articles/PMC3946950/