ACTH(6-9)PGP Peptide Protects SH-SY5Y Cells from the H2O2, tert-Butyl Hydroperoxide, and Cyanide Cytotoxicity via Prolif-eration Stimulation and Antioxidant-related Genes Induction

Autor: L.A. Andreeva, Myasoyedov Nf, Fomina-Ageeva Ev, Polina V Dudina, Akimov Mg, Bezuglov Vv

Stabilized melanocortin analog peptide ACTH(6-9)PGP (FRWGPGP) possess a wide range of neuroprotective activities. However, its mechanism of action remains poorly understood. In this paper, we studied the pro-proliferative and cytoprotective activity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018567d503181da0667f16ab48586518
https://doi.org/10.20944/preprints202103.0139.v1

The Interaction of the Endocannabinoid Anandamide and Paracannabinoid Lysophosphatidylinositol during Cell Death Induction in Human Breast Cancer Cells.

Autor: Akimov MG; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia., Gretskaya NM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia., Gorbacheva EI; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia., Khadour N; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia., Chernavskaya VS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia., Sherstyanykh GD; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia., Kovaleko TF; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia., Fomina-Ageeva EV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia., Bezuglov VV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 14; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 14.

N -Acyl Dopamines Induce Apoptosis in Endometrial Stromal Cells from Patients with Endometriosis.

Autor: Gamisonia AM; National Medical Research Center for Obstetrics, Gynecology and Perinatology Named after Academician V. I. Kulakov of the Ministry of Healthcare of Russian Federation, Akademika Oparina Str. 4, 117513 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya Str. 16/10, 117997 Moscow, Russia., Yushina MN; National Medical Research Center for Obstetrics, Gynecology and Perinatology Named after Academician V. I. Kulakov of the Ministry of Healthcare of Russian Federation, Akademika Oparina Str. 4, 117513 Moscow, Russia., Fedorova-Gogolina IA; National Medical Research Center for Obstetrics, Gynecology and Perinatology Named after Academician V. I. Kulakov of the Ministry of Healthcare of Russian Federation, Akademika Oparina Str. 4, 117513 Moscow, Russia., Akimov MG; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya Str. 16/10, 117997 Moscow, Russia., Eldarov CM; National Medical Research Center for Obstetrics, Gynecology and Perinatology Named after Academician V. I. Kulakov of the Ministry of Healthcare of Russian Federation, Akademika Oparina Str. 4, 117513 Moscow, Russia., Pavlovich SV; National Medical Research Center for Obstetrics, Gynecology and Perinatology Named after Academician V. I. Kulakov of the Ministry of Healthcare of Russian Federation, Akademika Oparina Str. 4, 117513 Moscow, Russia., Bezuglov VV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya Str. 16/10, 117997 Moscow, Russia., Gretskaya NM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya Str. 16/10, 117997 Moscow, Russia., Sukhikh GT; National Medical Research Center for Obstetrics, Gynecology and Perinatology Named after Academician V. I. Kulakov of the Ministry of Healthcare of Russian Federation, Akademika Oparina Str. 4, 117513 Moscow, Russia., Bobrov MY; National Medical Research Center for Obstetrics, Gynecology and Perinatology Named after Academician V. I. Kulakov of the Ministry of Healthcare of Russian Federation, Akademika Oparina Str. 4, 117513 Moscow, Russia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 30; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 30.

ACTH(6-9)PGP Peptide Protects SH-SY5Y Cells from H 2 O 2 , tert -Butyl Hydroperoxide, and Cyanide Cytotoxicity via Stimulation of Proliferation and Induction of Prosurvival-Related Genes.

Autor: Akimov MG; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia., Fomina-Ageeva EV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia., Dudina PV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia., Andreeva LA; Institute of Molecular Genetics of National Research Centre, Kurchatov Institute, Ploshchad' Akademika Kurchatova 2, 123182 Moscow, Russia., Myasoyedov NF; Institute of Molecular Genetics of National Research Centre, Kurchatov Institute, Ploshchad' Akademika Kurchatova 2, 123182 Moscow, Russia., Bezuglov VV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2021 Mar 26; Vol. 26 (7). Date of Electronic Publication: 2021 Mar 26.

In Vivo Targeted Metabolomic Profiling of Prostanit, a Novel Anti-PAD NO-Donating Alprostadil-Based Drug.

Autor: Shestakova KM; Laboratory of Pharmacokinetics and Metabolomic Analysis, Institute of Translational Medicine and Biotechnology, I.M. Sechenov First Moscow State Medical University, 2-4 Bolshaya Pirogovskaya St., 119991 Moscow, Russia., Moskaleva NE; Laboratory of Pharmacokinetics and Metabolomic Analysis, Institute of Translational Medicine and Biotechnology, I.M. Sechenov First Moscow State Medical University, 2-4 Bolshaya Pirogovskaya St., 119991 Moscow, Russia., Mesonzhnik NV; Laboratory of Pharmacokinetics and Metabolomic Analysis, Institute of Translational Medicine and Biotechnology, I.M. Sechenov First Moscow State Medical University, 2-4 Bolshaya Pirogovskaya St., 119991 Moscow, Russia., Kukharenko AV; Laboratory of Pharmacokinetics and Metabolomic Analysis, Institute of Translational Medicine and Biotechnology, I.M. Sechenov First Moscow State Medical University, 2-4 Bolshaya Pirogovskaya St., 119991 Moscow, Russia., Serkov IV; Institute of Physiologically Active Compounds RAS, Severniy pr., 1, 142432 Chernogolovka, Russia., Lyubimov II; Territory of Skolkovo Innovation Center, LLC 'Gurus BioPharm', Bolshoy Boulevard, 42 Building 1, 143026 Moscow, Russia., Fomina-Ageeva EV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, St. Miklukho-Maklaya, 16/10, 117997 Moscow, Russia., Bezuglov VV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, St. Miklukho-Maklaya, 16/10, 117997 Moscow, Russia., Akimov MG; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, St. Miklukho-Maklaya, 16/10, 117997 Moscow, Russia., Appolonova SA; Laboratory of Pharmacokinetics and Metabolomic Analysis, Institute of Translational Medicine and Biotechnology, I.M. Sechenov First Moscow State Medical University, 2-4 Bolshaya Pirogovskaya St., 119991 Moscow, Russia.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2020 Dec 13; Vol. 25 (24). Date of Electronic Publication: 2020 Dec 13.