Výsledky vyhledávání - "Akimitsu Sano"

Improved Separation and Determination of Phospholipids in Animal Tissues Employing Solid Phase Extraction

Autor: Takeo Kuriki, Taihei Miki, Akimitsu Sano, Emi Suzuki

Publikováno v: Biological and Pharmaceutical Bulletin. 20:299-303

Separation of five glycerophospholipids having different polar groups, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylserine (PS), phosphatidylglycerol (PG) and cardiolipin (CL), was investigated by means of solid-phase extracti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5149f6c7de7b795fe46037e9ca750c
https://doi.org/10.1248/bpb.20.299

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Studies on the Granulation Process of Granules for Tableting with a High Speed Mixer. II. Influence of Particle Size of Active Substance on Granulation

Autor: Yoshio Kanaya, Shiuji Kondo, Akimitsu Sano, Tatsuro Shiraishi, Hiroshi Yuasa

Publikováno v: Chemical and Pharmaceutical Bulletin. 43:654-659

In the process of granulation for tableting using theophylline as a model drug, the power consumption pattern and the physical properties of the granules were examined with varied particle sizes of theophylline. During kneading of the physical mixtur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2f5702a6aaa9658aad7e82abbbc7553
https://doi.org/10.1248/cpb.43.654

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Preparation of Piretanide Polymorphs and Their Physicochemical Properties and Dissolution Behaviors

Autor: Yoshihisa Matsuda, Makoto Otsuka, Tsuyoshi Tsujiyama, Yuji Chikaraishi, Akimitsu Sano

Publikováno v: Chemical and Pharmaceutical Bulletin. 42:1123-1128

Piretanide polymorphs were prepared by recrystallization using 27 organic solvents. We identified a new polymorphism, forms A and B, and 6 solvates. They were characterized by X-ray powder diffractometry, differential scanning calorimetry (DSC), ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0e1c55adbe5ea09c023a9821b005c56
https://doi.org/10.1248/cpb.42.1123

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Separation and Determination of Phospholipids in Plasma Employing Thin-Layer Chromatographic Plate with Concentration Zone or Solid Phase Extraction

Autor: Taihei Miki, Takeo Kuriki, Akimitsu Sano, Emi Suzuki

Publikováno v: Biological and Pharmaceutical Bulletin. 16:77-80

Two efficient extraction methods for phospholipids have been established employing a TLC plate with a concentration zone or a solid-phase extraction cartridge. First, small amounts of five authentic phospholipids, 10 to 100 micrograms each, were sepa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca9e778cd87b9233eec151e68da0aa2
https://doi.org/10.1248/bpb.16.77

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Particle Design of Tolbutamide by the Spherical Crystallization Technique. V. Improvement of Dissolution and Bioavailability of Direct Compressed Tablets Prepared Using Tolbutamide Agglomerated Crystals

Autor: Hirofumi Takeuchi, Akimitsu Sano, Yoshiaki Kawashima, Toshiyuki Niwa, Tomoaki Hino, Takeo Kuriki

Publikováno v: Chemical and Pharmaceutical Bulletin. 40:3030-3035

Tolbutamide (TBM) agglomerated crystals were prepared by three spherical crystallization techniques, the solvent change (SC) method, neutralization (NT) method and quasi-emulsion solvent diffusion (QESD) method (SC-A, SC-B, NT and QESD) agglomerated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0bcebe4a13898cfe4b26c4a75860ae95
https://doi.org/10.1248/cpb.40.3030

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Particle Design for Antidiabetic Drugs by the Spherical Crystallization Technique. IV. Assessment of Compressibility of Agglomerated Tolbutamide Crystals Prepared by Crystallization Technique

Autor: Takeo Kuriki, Akimitsu Sano, Tomoaki Hino, Hirofumi Takeuchi, Yoshiaki Kawashima, Toshiyuki Niwa

Publikováno v: Chemical and Pharmaceutical Bulletin. 40:1573-1581

Three different crystallization methods, i.e., the solvent change (SC) method, neutralization (NT) method and quasi-emulsion solvent diffusion (QESD) method, were employed to prepare agglomerated tolbutamide crystals (referred to as SC-A, SC-B, NT an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea5858bb81de73da4cb214cdd6c6fe0e
https://doi.org/10.1248/cpb.40.1573

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Particle design of tolbutamide by the spherical crystallization technique. III. Micromeritic properties and dissolution rate of tolbutamide spherical agglomerates prepared by the quasi-emulsion solvent diffusion method and the solvent change method

Autor: Toshiyuki Niwa, Akimitsu Sano, Yoshiaki Kawashima, Hirofumi Takeuchi, Takeo Kuriki, Tomoaki Hino

Publikováno v: Chemical and Pharmaceutical Bulletin. 38:733-739

With the objective of modifying the micromeritic properties of tolbutamide (i.e., to manufacture a highly functional powder form), particle design was attempted using a quasi-emulsion solvent diffusion (QESD) method, and the micromeritic properties a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49965437c804fbff36cd784484e0bbb6
https://doi.org/10.1248/cpb.38.733

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