Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Akimitsu Okamoto"'
Autor:
Shinya Yamahira, Hidefumi Mitsuno, Misato Yamaoka, Teruyuki Nagamune, Akimitsu Okamoto, Ryohei Kanzaki, Satoshi Yamaguchi
Publikováno v:
Biosensors and Bioelectronics: X, Vol 18, Iss , Pp 100473- (2024)
A technology that can effectively distinguish between various odorants with high sensitivity and selectivity has numerous applications ranging from water quality testing to disease diagnosis. Here, we report a cell-based odorant-sensing display that
Externí odkaz:
https://doaj.org/article/f11fab73991845b8bad8ec15b4e8c3c5
Autor:
Melvin Pan, Christiane Zorbas, Maki Sugaya, Kensuke Ishiguro, Miki Kato, Miyuki Nishida, Hai-Feng Zhang, Marco M. Candeias, Akimitsu Okamoto, Takamasa Ishikawa, Tomoyoshi Soga, Hiroyuki Aburatani, Juro Sakai, Yoshihiro Matsumura, Tsutomu Suzuki, Christopher G. Proud, Denis L. J. Lafontaine, Tsuyoshi Osawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Small molecules that target RNA Polymerase I inhibit ribosome biogenesis to activate p53 through the nucleolar surveillance response pathway. Here, the authors show that p53 induction by ribosome stress is dependent on extracellular glutamine availab
Externí odkaz:
https://doaj.org/article/5a2c48021da748188909409721466a55
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
DNA methylation plays an important physiological function in cells, and environmental changes result in fluctuations in DNA methylation levels. Metal ions have become both environmental and health concerns, as they have the potential to disrupt the g
Externí odkaz:
https://doaj.org/article/e4cf6f1347fc4a999c5a5a86f71e0023
Autor:
Ryota Itaya, Wakana Idei, Takashi Nakamura, Tatsuya Nishihara, Ryohsuke Kurihara, Akimitsu Okamoto, Kazuhito Tanabe
Publikováno v:
ACS Omega, Vol 6, Iss 47, Pp 31595-31604 (2021)
Externí odkaz:
https://doaj.org/article/06eb02dcc7164ac9baf19b267a6fd4a8
Autor:
Sae Suzuki, Yuya Nakajima, Naoki Kamo, Akihisa Osakabe, Akimitsu Okamoto, Gosuke Hayashi, Hiroshi Murakami
Publikováno v:
Molecules, Vol 28, Iss 9, p 3655 (2023)
Thiol catalysts are essential in native chemical ligation (NCL) to increase the reaction efficiency. In this paper, we report the use of thiocholine in chemical protein synthesis, including NCL-based peptide ligation and metal-free desulfurization. E
Externí odkaz:
https://doaj.org/article/a824ab86b6404c34818ed9b9438ba516
Autor:
Akimitsu Okamoto
Publikováno v:
Applied Microscopy, Vol 49, Iss 1, Pp 1-7 (2019)
Abstract Fluorescence imaging of nucleic acids is a very important technique necessary to understand gene expression and the resulting changes in cell function. This mini-review focuses on sequence-specific fluorescence imaging of intracellular RNA a
Externí odkaz:
https://doaj.org/article/33274f9424c64ee29e8bb5eafe692b09
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95750 (2014)
To understand the spatiotemporal changes in cellular status that occur during embryonic development, it is desirable to detect simultaneously the expression of genes, proteins, and epigenetic modifications in individual embryonic cells. A technique t
Externí odkaz:
https://doaj.org/article/4933d66027b04f24abf6e244b9bbafc1
Publikováno v:
Journal of Nucleic Acids, Vol 2011 (2011)
The development of a reaction for detecting the presence/absence of one methyl group in a long DNA strand is a chemically and biologically challenging research subject. A newly designed chemical assay on a chip for the typing of DNA methylation has b
Externí odkaz:
https://doaj.org/article/8a485124c4174926b20c8d0310d3ac41
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e13003 (2010)
BACKGROUND: Imaging the behavior of RNA in a living cell is a powerful means for understanding RNA functions and acquiring spatiotemporal information in a single cell. For more distinct RNA imaging in a living cell, a more effective chemical method t
Externí odkaz:
https://doaj.org/article/0a7d43ef47a6439b9203a2f649eaa730
One-Pot, Photocontrolled Enzymatic Assembly of the Structure-Defined Heterotypic Polyubiquitin Chain
Autor:
Takafumi Furuhata, Phebee Angeline Devadasan Racheal, Iori Murayama, Usano Toyoda, Akimitsu Okamoto
Publikováno v:
Journal of the American Chemical Society. 145:11690-11700
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7169057e7811e08afd8cb2694172c7b1
https://doi.org/10.1021/jacs.3c01912
https://doi.org/10.1021/jacs.3c01912