Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Akil Merchant"'
Autor:
Layla Shojaie, Jacob M. Bogdanov, Helia Alavifard, Mahmoud G. Mohamed, Aria Baktash, Myra Ali, Simeon Mahov, Sue Murray, Gary C. Kanel, Zhang-Xu Liu, Fumito Ito, Gino K. In, Akil Merchant, William Stohl, Lily Dara
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-16 (2024)
Abstract Immune checkpoints (CTLA4 & PD-1) are inhibitory pathways that block aberrant immune activity and maintain self-tolerance. Tumors co-opt these checkpoints to avoid immune destruction. Immune checkpoint inhibitors (ICIs) activate immune cells
Externí odkaz:
https://doaj.org/article/1c457dccc2cc49eebdd7ce8656ba227a
Autor:
Kevin Kelly, Matt Coffey, Tomás Pascual, Aleix Prat, Luis Manso, Thomas Heineman, Fernando Salvador, Joaquín Gavilá, Houra Loghmani, Richard Trauger, Akil Merchant, Julian Olea, Homa Dadrastoussi, Eduardo Fernandez Hernandez, Hugo Lara Martinez, Kaijin Wu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/03ed36044d9b4a3ebd44195b6772b464
Autor:
Monirath Hav, Katsuyoshi Takata, Lauren Chong, Alexander Xu, Aixiang Jiang, Tomohiro Aoki, Alicia Gamboa, Anthony Colombo, Yifan Yin, Joseph Lownik, Christian Steidl, Akil Merchant
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/dce449b95f9e40778eca9462f330853e
Autor:
Elizabeth Qi, George Courcoubetis, Emmett Liljegren, Ergueen Herrera, Nathalie Nguyen, Maimoona Nadri, Sara Ghandehari, Elham Kazemian, Karen L. Reckamp, Noah M. Merin, Akil Merchant, Jeremy Mason, Jane C. Figueiredo, Stephanie N. Shishido, Peter Kuhn
Publikováno v:
EBioMedicine, Vol 90, Iss , Pp 104519- (2023)
Summary: Background: Post-acute COVID-19 syndrome (PACS) is linked to severe organ damage. The identification and stratification of at-risk SARS-CoV-2 infected individuals is vital to providing appropriate care. This exploratory study looks for a pot
Externí odkaz:
https://doaj.org/article/df8ee0c66b6142f0b64e855f06d2df14
Autor:
Libere J. Ndacayisaba, Kate E. Rappard, Stephanie N. Shishido, Carmen Ruiz Velasco, Nicholas Matsumoto, Rafael Navarez, Guilin Tang, Pei Lin, Sonia M. Setayesh, Amin Naghdloo, Ching-Ju Hsu, Carlisle Maney, David Symer, Kelly Bethel, Kevin Kelly, Akil Merchant, Robert Orlowski, James Hicks, Jeremy Mason, Elisabeth E. Manasanch, Peter Kuhn
Publikováno v:
Current Oncology, Vol 29, Iss 5, Pp 2954-2972 (2022)
Multiple myeloma is an incurable malignancy that initiates from a bone marrow resident clonal plasma cell and acquires successive mutational changes and genomic alterations, eventually resulting in tumor burden accumulation and end-organ damage. It h
Externí odkaz:
https://doaj.org/article/855f3a6e0fcc4ed8a712cc135212c4c0
Autor:
Yapei Huang, Juliana E. Shin, Alexander M. Xu, Changfu Yao, Sandy Joung, Min Wu, Ruan Zhang, Bongha Shin, Joslyn Foley, Simeon B. Mahov, Matthew E. Modes, Joseph E. Ebinger, Matthew Driver, Jonathan G. Braun, Caroline A. Jefferies, Tanyalak Parimon, Chelsea Hayes, Kimia Sobhani, Akil Merchant, Sina A. Gharib, Stanley C. Jordan, Susan Cheng, Helen S. Goodridge, Peter Chen
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105209- (2022)
Summary: SARS-CoV-2 vaccines have unquestionably blunted the overall impact of the COVID-19 pandemic, but host factors such as age, sex, obesity, and other co-morbidities can affect vaccine efficacy. We identified individuals in a relatively healthy
Externí odkaz:
https://doaj.org/article/01a952f077a642f7a2bb1d61db9271c4
Autor:
Tucker Lemos, Akil Merchant
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The Hedgehog (HH) pathway is a promising therapeutic target in hematological malignancies. Activation of the pathway has been tied to greater chances of relapse and poorer outcomes in several hematological malignancies and inhibiting the pathway has
Externí odkaz:
https://doaj.org/article/cf7940ec84264c9a9dff9994446ab061
Autor:
Alexander M. Xu, Dalin Li, Joseph E. Ebinger, Emebet Mengesha, Rebecca Elyanow, Rachel M. Gittelman, Heidi Chapman, Sandy Joung, Gregory J. Botwin, Valeriya Pozdnyakova, Philip Debbas, Angela Mujukian, John C. Prostko, Edwin C. Frias, James L. Stewart, Arash A. Horizon, Noah Merin, Kimia Sobhani, Jane C. Figueiredo, Susan Cheng, Ian M. Kaplan, Dermot P. B. McGovern, Akil Merchant, Gil Y. Melmed, Jonathan Braun
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
T-cells specifically bind antigens to induce adaptive immune responses using highly specific molecular recognition, and a diverse T-cell repertoire with expansion of antigen-specific clones can indicate robust immune responses after infection or vacc
Externí odkaz:
https://doaj.org/article/b9f0c827dbb943ba89561bcaec2c555a
Autor:
Geetanjali D. Datta, Marie Lauzon, Sarah-Jeanne Salvy, Shehnaz K. Hussain, Sara Ghandehari, Akil Merchant, Noah M. Merin, Karen Reckamp, Jane C. Figueiredo
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
The COVID-19 pandemic has the potential to impact long-standing efforts to increase adherence to cancer screening guidelines. Healthcare workers (HCWs) experienced significant hardship, but generally have greater access to preventive services, making
Externí odkaz:
https://doaj.org/article/7ac30836cabb44908b4124bc1c9b71c5
Autor:
Sonia Sharma, Jane C Figueiredo, Michael Karin, Margo Minissian, Nancy Sun, Susan Cheng, Patrick Botting, Joseph E Ebinger, Eric Luong, Elizabeth H Kim, Trevor Trung Nguyen, Dalin Li, Dermot P B McGovern, Christine M Albert, Anders H Berg, Kimia Sobhani, Mohit Jain, Sandy Joung, Yunxian Liu, Mona Alotaibi, Justyna Fert-Bober, Jennifer E Van Eyk, Moshe Arditi, Jonathan G Braun, Gregory J Botwin, Akil Merchant, Aleksandra Binek, Jonathan D Grein, Wohaib Hasan, Mir Henglin, Shehnaz K Hussain, Noah Merin, Peggy B Miles, Koen Raedschelders, Mohamad A Rashid, Celine E Riera, Richard V Riggs, Sarah Sternbach, Warren G Tourtellotte
Publikováno v:
BMJ Open, Vol 11, Iss 2 (2021)
Objective We sought to determine the extent of SARS-CoV-2 seroprevalence and the factors associated with seroprevalence across a diverse cohort of healthcare workers.Design Observational cohort study of healthcare workers, including SARS-CoV-2 serolo
Externí odkaz:
https://doaj.org/article/a297af3ae45f434f8c43285a6515dc35