Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Akiko Yamamuro"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 153, Iss 2, Pp 73-83 (2023)
Schwann cells and oligodendrocytes secrete proteins that promote neuron survival, but their role in amyotrophic lateral sclerosis (ALS) is unclear. To address this question, we evaluated the effect of molecules secreted by Schwann cells on reactive o
Externí odkaz:
https://doaj.org/article/1cf8b646f40a4370be6035d83bbfd256
Publikováno v:
Journal of Pharmacological Sciences, Vol 148, Iss 1, Pp 41-50 (2022)
We previously reported that dopamine (DA) attenuated lipopolysaccharide (LPS)-induced expression of proinflammatory cytokines through the formation of DA quinone (DAQ) in murine microglial cell line BV-2 and primary murine microglial cells. To reveal
Externí odkaz:
https://doaj.org/article/cc034e2eba9b4be78ff074245ab9db60
Autor:
Yuki Ishimaru, Akihide Sumino, Fumiya Shibagaki, Akiko Yamamuro, Yasuhiro Yoshioka, Sadaaki Maeda
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Age-associated loss of retinal ganglion cells (RGCs) causes visual deficits, but there is not yet any therapeutic agent to prevent the loss of these cells. Herein, we report that apelin, an endogenous peptide ligand of APJ receptor, is protective aga
Externí odkaz:
https://doaj.org/article/56ae3a1745c8470bbe8bf4e95daaa979
Autor:
Yuki Ishimaru, Akihide Sumino, Daiki Kajioka, Fumiya Shibagaki, Akiko Yamamuro, Yasuhiro Yoshioka, Sadaaki Maeda
Publikováno v:
Journal of Pharmacological Sciences, Vol 133, Iss 1, Pp 34-41 (2017)
Glutamate excitotoxicity mediated by N-methyl-d-aspartate (NMDA) receptors is an important cause of retinal ganglion cell death in glaucoma. To elucidate whether apelin protects against retinal neuronal cell death, we examined protective effects of e
Externí odkaz:
https://doaj.org/article/507b611bf9dc4a69aacd45b0b5faa4cb
Autor:
Yasuhiro Yoshioka, Yuta Sugino, Azusa Tozawa, Akiko Yamamuro, Atsushi Kasai, Yuki Ishimaru, Sadaaki Maeda
Publikováno v:
Journal of Pharmacological Sciences, Vol 130, Iss 2, Pp 51-59 (2016)
Dopamine (DA) has been suggested to modulate functions of glial cells including microglial cells. To reveal the regulatory role of DA in microglial function, in the present study, we investigated the effect of DA on lipopolysaccharide (LPS)-induced n
Externí odkaz:
https://doaj.org/article/15d66dd86fde45bc82b3329b143a6597
Autor:
Akiko Yamamuro, Takashi Kishino, Yu Ohshima, Yasuhiro Yoshioka, Tomoki Kimura, Atsushi Kasai, Sadaaki Maeda
Publikováno v:
Journal of Pharmacological Sciences, Vol 115, Iss 2, Pp 239-243 (2011)
The present study investigated the function of caspase-4 in endoplasmic reticulum (ER) stress–induced apoptosis in human neuronal cell line SH-SY5Y. Tunicamycin, which is known to induce ER stress, activated both caspase-9 and caspase-4, and the ac
Externí odkaz:
https://doaj.org/article/24981e1d46fe4144a568e0bb6a171c6b
Publikováno v:
Journal of Pharmacological Sciences, Vol 113, Iss 2, Pp 153-160 (2010)
The present study examined the effect of the nitric oxide (NO) donor NOC18 on lipopolysaccharide (LPS)-induced NO production to investigate a regulation mechanism of NO production by microglial cells. LPS increased the levels of NO and inducible NO s
Externí odkaz:
https://doaj.org/article/01787303a58d41299e3220fee4b77b1d
Publikováno v:
Journal of Pharmacological Sciences, Vol 92, Iss 2, Pp 153-156 (2003)
The present study examines the effect of the cognition enhancer (1R)-1-benzo[b]thiophen-5-yl-2-[2-(diethylamino)ethoxy]ethan-1-ol hydrochloride (T-588) on neuronal injury induced by serum deprivation or amyloid-β protein (Aβ). T-588 protected parti
Externí odkaz:
https://doaj.org/article/2888858a9c4d4c7ca52b580cb6dcfd8f
Autor:
Atsushi Kasai, Toshihiko Kinjo, Rie Ishihara, Ikumi Sakai, Yuki Ishimaru, Yasuhiro Yoshioka, Akiko Yamamuro, Kumiko Ishige, Yoshihisa Ito, Sadaaki Maeda
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23968 (2011)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the selective loss of motor neurons. Recent studies have implicated that chronic hypoxia and insufficient vascular endothelial growth factor (VEGF)-dependent neuropro
Externí odkaz:
https://doaj.org/article/ba23bed183124700ad4f747ec17f2f65
Autor:
Akiko Yamamuro-Tanabe, Yurika Mukai, Wataru Kojima, Siyuan Zheng, Naoko Matsumoto, Shoho Takada, Mao Mizuhara, Yasuhiro Kosuge, Yuki Ishimaru, Yasuhiro Yoshioka
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease with selective degeneration of motor neurons. It has been reported that an increase in the levels of inflammatory cytokines and glial cells such as reactive astrocytes is close
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f397a5236d51eeac9517fea32843589
https://doi.org/10.21203/rs.3.rs-2513131/v1
https://doi.org/10.21203/rs.3.rs-2513131/v1
