Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Akiko Sugahara-Tobinai"'
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128210 (2015)
Osteoclasts play an important role in bone metabolism, but their exact role in fracture healing remains unclear. DAP12 is an immunoadaptor protein with associated immunoreceptors on myeloid lineage cells, including osteoclasts. Its deficiency causes
Externí odkaz:
https://doaj.org/article/eb53c3cc03de44e59aa35399f3b6dc89
Autor:
Shota Endo, Dai Kezuka, Yi Li Wong, So Itoi, Toshiyuki Takai, Masanori Inui, Akiko Sugahara-Tobinai, Mei Tzu Su, Keiichi Murakami, Ari Itoh-Nakadai, Shotaro Miyamoto, Hisashi Arase, Karin Ono, Maika Takahashi, Kouyuki Hirayasu
Publikováno v:
International Immunology. 33:447-458
The extracellular matrix (ECM) is the basis for virtually all cellular processes and is also related to tumor metastasis. Fibronectin (FN), a major ECM macromolecule expressed by different cell types and also present in plasma, consists of multiple f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5561878267420ef558511791661303de
https://doi.org/10.1093/intimm/dxab028
https://doi.org/10.1093/intimm/dxab028
Autor:
Yi Li Wong, Toshiyuki Takai, Dai Kezuka, So Itoi, Mei Tzu Su, Masanori Inui, Akiko Sugahara-Tobinai, Shota Endo
Publikováno v:
International Immunology. 31(6):397-406
AbstractImmune homeostasis is critically regulated by the balance between activating and inhibitory receptors expressed on various immune cells such as T and B lymphocytes, and myeloid cells. The inhibitory receptors play a fundamental role in the im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ccce8b74b6fc8004a145b36d8b626ab
http://hdl.handle.net/10097/00127189
http://hdl.handle.net/10097/00127189
Autor:
Satoru Kumaki, Takaya Metoki, Masanori Inui, Toshiyuki Takai, Yo-hei Watanabe, Akiko Sugahara-Tobinai, Ryoichi Onuma
Publikováno v:
The Pediatric infectious disease journal. 38(4)
Kawasaki disease (KD) is an acute, systemic vasculitis syndrome that occurs in children. The clinical symptoms and epidemiologic features of KD strongly suggest that KD is triggered by unidentified infectious agents in genetically predisposed patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d3830d9695ff878ad8abf9664f81f8
https://pubmed.ncbi.nlm.nih.gov/30882741
https://pubmed.ncbi.nlm.nih.gov/30882741
Autor:
Tomonori Ishii, Hidehiro Fukuyama, Masanori Inui, Ari Itoh-Nakadai, Hideo Harigae, Toshiyuki Takai, Tomohiro Kurosaki, Hiroshi Fujii, Akiko Sugahara-Tobinai
Publikováno v:
International Immunology. 28:597-604
Plasmablasts and plasma cells (PBs and PCs) producing pathogenic auto-antibodies in patients with systemic autoimmune diseases could be a better target for specific therapies for the disease than general immunosuppression or pan- or activated B-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b939758eccc21f8191b733f049711b12
https://doi.org/10.1093/intimm/dxw044
https://doi.org/10.1093/intimm/dxw044
Autor:
Toshiyuki Takai, Matsuyuki Shirota, Atsuko Kayaba, Masanori Inui, Kunimichi Niibe, Ryo Funayama, Keiko Nakayama, Akiko Sugahara-Tobinai, Ari Itoh-Nakadai, Yi Li Wong
Publikováno v:
International immunology. 30(6)
Plasma cells (PCs) acquiring long lifespans in the bone marrow (BM) play a pivotal role in the humoral arm of immunological memory. The PCs reside in a special BM niche and produce antibodies against past-encountered pathogens or vaccine components f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50513d58f24761b1bf5ce65e0defbd92
https://pubmed.ncbi.nlm.nih.gov/29529192
https://pubmed.ncbi.nlm.nih.gov/29529192
Autor:
Yasuyoshi Kanari1 kanari@idac.tohoku.ac.jp, Akiko Sugahara-Tobinai1 akiko@idac.tohoku.ac.jp, Haruka Takahashi1 haruka-t@idac.tohoku.ac.jp, Masanori Inui1 inui@idac.tohoku.ac.jp, Akira Nakamura1,2 aki-n@kanazawa-med.ac.jp, Sachiko Hirose3 sacchi@juntendo.ac.jp, Toshiyuki Takai1 tostakai@idac.tohoku.ac.jp
Publikováno v:
BMC Immunology. 2014, Vol. 15 Issue 1, p1-23. 23p.
Publikováno v:
Annals of Research in Sport and Physical Activity. :119-120
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec3275f99be280f3294f8be18503a7cb
https://doi.org/10.14195/2182-7087_ex2018_35
https://doi.org/10.14195/2182-7087_ex2018_35
Autor:
Atsushi Nakano, Toshiyuki Takai, Yuzuru Sakamoto, Akiko Sugahara-Tobinai, Masanori Inui, Kumiko Hirano, Yumi Ito-Matsuoka, Shota Endo, Lars Nitschke, Jun Tanaka
Publikováno v:
Open Journal of Immunology. :149-160
A therapeutic preparation of polyclonal human IgG, i.e., intravenous immunoglobulin (IVIg), has been employed to treat several inflammatory and autoimmune disorders. B cells are supposed to be a target of IVIg, but the molecular mechanism is elusive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ed475b66146ca7448c7afc522db8312
https://doi.org/10.4236/oji.2012.24019
https://doi.org/10.4236/oji.2012.24019
Signal adaptor DAP10 associates with MDL-1 and triggers osteoclastogenesis in cooperation with DAP12
Autor:
Marco Colonna, Naoko Aoki, Akira Nakamura, Toshiyuki Takai, Tsutomu Maeda, Akiko Sugahara-Tobinai, Yuki Kikuchi, Shota Endo, Shion Fujimura, Masanori Inui, Atsushi Kumanogoh
Publikováno v:
Proceedings of the National Academy of Sciences. 106:4816-4821
Osteoclasts, cells of myeloid lineage, play a unique role in bone resorption, maintaining skeletal homeostasis in concert with bone-producing osteoblasts. Osteoclast development and maturation (osteoclastogenesis) is driven by receptor activator of N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd08d6a69713e944152cee14bbdb7ea6
https://doi.org/10.1073/pnas.0900463106
https://doi.org/10.1073/pnas.0900463106