Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Akiko Morio"'
1
Multiple Genetic Factors in Olanzapine-Induced Weight Gain in Schizophrenia Patients
Autor: Yukitaka Morita, Shigetoshi Kuroda, Akiko Morio, Takeshi Ishihara, Tatsuya Kotaka, Akira Nomura, Hiroshi Ujike, Masafumi Kodama, Yuko Okahisa
Publikováno v: The Journal of Clinical Psychiatry. 69:1416-1422
OBJECTIVE One of the clinically significant adverse effects of olanzapine treatment is weight gain, which shows substantial inter-individual differences and may be influenced by genetic variation. The aim of this investigation was identification of g
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355f7be75aadf932c9b96c2261e3e66d
https://doi.org/10.4088/jcp.v69n0909
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2
No Association between CART (Cocaine- and Amphetamine-Regulated Transcript) Gene and Methamphetamine Dependence
Autor: Shigetoshi Kuroda, Makiko Kishimoto, Mitsuhiko Yamada, Yoshimoto Sekine, Tokutaro Komiyama, Yukitaka Morita, T. Inada, Akiko Morio, Mutsuo Harano, Hiroshi Ujike, Masaomi Iyo, Akira Nomura, Norio Ozaki, Nakao Iwata, Yuji Tanaka, Ichiro Sora, Kyohei Otani
Publikováno v: Annals of the New York Academy of Sciences. 1074:411-417
Cocaine- and amphetamine-regulated transcript (CART) was originally discovered as a peptide that increased in the rat striatum after injection of a psychostimulant drug, such as cocaine or amphetamine, and is suggested to play potential roles in drug
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e091b22827c74b2fd7474e84a712b01c
https://doi.org/10.1196/annals.1369.041
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3
Association study of the tumor necrosis factor-alpha gene and its 1A receptor gene with methamphetamine dependence
Autor: Yukitaka Morita, T. Inada, Yuji Tanaka, Yoshimoto Sekine, Ichiro Sora, Akira Nomura, Akiko Morio, Toru Hori, Kyohei Otani, Shigetoshi Kuroda, Norio Ozaki, Mutsuo Harano, Tokutaro Komiyama, Makiko Kishimoto, Mitsuhiko Yamada, Hiroshi Ujike, Masaomi Iyo, Nakao Iwata
Publikováno v: Annals of the New York Academy of Sciences. 1074
Recent preclinical findings that repeated treatment with methamphetamine (METH) induced an increase in tumor necrosis factor-alpha (TNF-alpha) mRNA in some brain regions and that TNF-alpha blocked METH neurotoxicity and rewarding effects suggest TNF-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc8d54a67917ec46a2e22a54a35c340
https://pubmed.ncbi.nlm.nih.gov/17105909
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4
A genetic variant of the serine racemase gene is associated with schizophrenia
Autor: Yukitaka Morita, Masayuki Matsushita, Yuko Okahisa, Akiko Morikawa, Akiko Morio, Yuji Tanaka, Kyohei Otani, Tatsuya Kotaka, Hiroshi Ujike, Makiko Kishimoto, Shigetoshi Kuroda, Kiyoshi Zaitsu, Kenji Hamase
Publikováno v: Biological psychiatry. 61(10)
Background Serine racemase (SRR) is a brain-enriched enzyme that converts l -serine to d -serine, which acts as an endogenous ligand of N-methyl d -aspartate (NMDA) receptors. Dysfunction of SRR may reduce the function of NMDA receptors and susceptib
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c3d541190c46335036eecfb0b13052
https://pubmed.ncbi.nlm.nih.gov/17067558
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5
Genetic variant of prodynorphin gene is risk factor for methamphetamine dependence
Autor: Norio Ozaki, Tokutaro Komiyama, Mitsuhiko Yamada, Akira Nomura, Yuji Tanaka, Toshiya Inada, Ichiro Sora, Yukitaka Morita, Shigetoshi Kuroda, Yoshimoto Sekine, Nakao Iwata, Kyohei Otani, Makiko Kishimoto, Akiko Morio, Hiroshi Ujike, Masaomi Iyo, Mutsuo Harano
Publikováno v: Neuroscience letters. 400(1-2)
Previous studies have indicated that genetic factors substantially affect development of substance use disorders, including methamphetamine dependence. Prodynorphin (PDYN) is an opioid peptide precursor that yields dynorphins, endogenous κ opioid-re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b6fef8fe010f3276d875750542de97
https://pubmed.ncbi.nlm.nih.gov/16529859
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6
The ZDHHC8 gene did not associate with bipolar disorder or schizophrenia
Autor: Hiroshi Ujike, Makiko Kishimoto, Kyohei Otani, Yuji Tanaka, Akira Nomura, Shigetoshi Kuroda, Naohiko Uchida, Yukitaka Morita, Akiko Morio
Publikováno v: Neuroscience letters. 390(3)
The zinc finger and DHHC domain-containing protein 8 (ZDHHC8) gene is located on chromosome 22q11, which several genome scans have provided repeated evidence for a significant linkage with bipolar disorder (BPD) and schizophrenia. A recent study reve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50150a29e291520d13a002e1ae42192
https://pubmed.ncbi.nlm.nih.gov/16150541
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7
The X-box binding protein 1 (XBP1) gene is not associated with methamphetamine dependence
Autor: Naohiko Uchida, Yoshimoto Sekine, Akira Nomura, Yukitaka Morita, Toshiya Inada, Mutsuo Harano, Nakao Iwata, Yuji Tanaka, Ichiro Sora, Norio Ozaki, Masaomi Iyo, Kyohei Otani, Mitsuhiko Yamada, Akiko Morio, Hiroshi Ujike, Makiko Kishimoto, Tokutaro Komiyama
Publikováno v: Neuroscience letters. 383(1-2)
Bipolar disorder has known as a high risk factor for substance abuse and dependence such as alcohol and illegal drugs. Recently, Kakiuchi et al. reported that the −116C/G polymorphism in the promoter region of the X-box binding protein 1 (XBP-1) ge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5868827fceb7601e3554840c6a806191
https://pubmed.ncbi.nlm.nih.gov/15936534
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